Klinik örneklerden mikobakterilerin izolasyonunda Versa Trec yönteminin araştırılması ve suşların Rep PCR yöntemiyle genotiplendirilmesi

We demonstrate the generation of a 1.1-1.7µm supercontinuum in a 1.3m long air suspended-core tellurite holey-fiber with a nominal zero-dispersion wavelength of ~1.38µm. The fiber is pumped at 1.06µm with a 20ps pulsed fiber laser. The high Raman gain-coefficient of tellurite glass is attributed a key role in the supercontinuum generation

Fiber MOPA seeded difference frequency generation as a tuneable source for THz tomography

The aim of this project is to demonstrate terahertz tomography, operating at millisecond image frame rates. The system will be based around a new high-power laser-diode driven nanosecond fibre-laser THz source, using difference-frequency generation, and pyroelectric detector arrays. The demonstrator will employ novel multi-channel THz tomography to map major species concentrations and temperature field distributions in high-pressure flames operating under sooting conditions. The proposed technology will also open the way to fast benchtop THz tomographs with applications in a wide area of science and engineering

Impact of Age on the Importance of Systolic and Diastolic Blood Pressures for Stroke Risk:The MOnica, Risk, Genetics, Archiving, and Monograph (MORGAM) Project

This study investigates age-related shifts in the relative importance of systolic (SBP) and diastolic (DBP) blood pressures as predictors of stroke and whether these relations are influenced by other cardiovascular risk factors. Using 34 European cohorts from the MOnica, Risk, Genetics, Archiving, and Monograph (MORGAM) Project with baseline between 1982 and 1997, 68 551 subjects aged 19 to 78 years, without cardiovascular disease and not receiving antihypertensive treatment, were included. During a mean of 13.2 years of follow-up, stroke incidence was 2.8%. Stroke risk was analyzed using hazard ratios per 10-mm Hg/5-mm Hg increase in SBP/DBP by multivariate-adjusted Cox regressions, including SBP and DBP simultaneously. Because of nonlinearity, DBP was analyzed separately for DBP ≥71 mm Hg and DBP <71 mm Hg. Stroke risk was associated positively with SBP and DBP ≥71 mm Hg (SBP/DBP ≥71 mm Hg; hazard ratios: 1.15/1.06 [95% CI: 1.12–1.18/1.03–1.09]) and negatively with DBP <71 mm Hg (0.88[0.79–0.98]). The hazard ratio for DBP decreased with age (P<0.001) and was not influenced by other cardiovascular risk factors. Taking into account the age×DBP interaction, both SBP and DBP ≥71 mm Hg were significantly associated with stroke risk until age 62 years, but in subjects older than 46 years the superiority of SBP for stroke risk exceeded that of DBP ≥71 mm Hg and remained significant until age 78 years. DBP <71 mm Hg became significant at age 50 years with an inverse relation to stroke risk. In Europeans, stroke risk should be assessed by both SBP and DBP until age 62 years with increased focus on SBP from age 47 years. From age 62 years, emphasis should be on SBP without neglecting the potential harm of very low DBP