On a numerical algorithm for uncertain system

A numerical method for computing stable control signals for system with bounded input disturbance is developed. The algorithm is an elaboration of the gradient technique and variable metric method for computing control variables in linear and non-linear optimization problems. This method is developed for an integral quadratic problem subject to a dynamic system with input bounded uncertainty

Mandatory or Flexible: Whither Retirement Age Policy?

The debate over whether to end mandatory retirement age policy in favor of flexible retirement policy has heightened. It is argued that it is wasteful to compel productive workers to retire at an arbitrary chronological age and that productivity should be the correct criterion for continued employment. This paper examines the preference between mandatory and flexible retirement age policies based on a survey conducted among workers in Lagos State, the former federal capital of Nigeria. It evaluates the impact of eliminating mandatory retirement age policy on the productivity of Nigerian workers. Particularly, the study investigates the influence of age, gender, income, and duration to retirement on workers’ preference for the type of retirement age policy. The study found that all the factors of interest influence employees’ preference for type of retirement plan and employees are indeed more disposed to flexible retirement. It also found that flexible policy will have a positive welfare effect as many employees can then take care of their extended span of dependants for a longer period and employee productivity will also be improved. Key words: Retirement, Mandatory, Flexible, Pension Plan, Extended Family System

PERFORMANCE EVALUATION OF ENERGY-SAVING BULBS IN SELECTED NIGERIAN LOCATIONS WITH ARTIFICIAL NEURAL NETWORK MODELLING

The performance evaluation of energy-saving bulbs in the Nigerian market is crucial in assisting energy auditing, which is beneficial to producers and consumers of electricity. Specifically, the high-power bills issued monthly by Electricity Distribution Company in most parts of Nigeria have made Nigerians in our various domestic homes embrace the latest lighting technology that consumes less energy.In this study, lighting system data were obtained from twenty-four households from different geographical zones in Nigeria. The performance evaluation of compact fluorescent light(CFL) bulbs was investigated and the observation was predicted with artificial neural networks (ANN) to enhance informed policy formulation and decision-makingResults showed that CFL bulbs givehigh-quality light that is cost-effective and environmentally friendly. ANN predicted the observation with high accuracie

SENSITIVITY ANALYSIS OF HYBRIDIZED WIND/PV ENERGY SYSTEM FOR POWERING TELECOMMUNICATION MAST IN LAGOS SOUTH-WEST NIGERIA

Power delivery micro-grid of hybridized wind and solar system installations keep growing worldwide. There is a great economic advantage in the use of cleaner renewable energy for power generation in the telecommunication industries, especially in remote areas. This studyanalyses the effect of three wind speed fluctuationsor levels on a hybridizedwind energy system’s electricity production for a typical three (3) BTS telecommunication mast using Hybrid Optimization Model for Energy Resources (HOMER)PRO software in Lagos south-western Nigeria as a case study. The economic implication of energy at the different wind speed levels investigated was also derived. From the obtained results, a wind speed of 4, 4.22, and 5 m/s gave an annual electric production of 39,950, 39,050, and 39,250 kWh and energy cost of 195, 192, and ₦175, respectively. This result is useful for the techno-economic operation of hybridized wind/solar system powered by three (3) BTS telecommunication masts

MODELLING AND OPTIMIZATION OF COEFFICIENT OF PERFORMANCE OF LOWER TEMPERATURE CYCLE OF TWO-STEP REFRIGERATION SYSTEMS

The coefficient of performance (COP) of a single-stage refrigeration system is low, thus there is a need for two-step refrigeration systems when there is a desire to have an evaporator temperature that is below -25 oC. The COP of the lower temperature cycle of the two-step refrigeration systems is a function of the COP of the refrigeration systems.This research aimed at optimizing COP of the lower temperature cycle of two-step refrigeration systems using eco-friendly refrigerants.Thermodynamic analysis of these refrigeration systems was performed by varying seven operating parameters. R-134a was used in the high-temperature cycle (HTC) and R-23 was used in the low-temperature cycle (LTC). The coefficient of performance of the lower temperature cycle (COP.REF[LTC]) of the refrigeration systems was optimized using Half Factorial Design of Design-Expert 12.0.1. The influence of the condensing temperature (TC,HTC),evaporating temperature (TE,HTC), cascade temperature difference (∆TCAS,DIFF), evaporating temperature (TE,LTC), superheating temperature (TSUP,LTC), sub-cooling temperature (TSUB,LTC), and refrigerant mass Flow rate (ṁHTC)was investigated on the values of COP.REF[LTC] of the refrigeration systems. The highest value of COP.REF[LTC] (18.1) was obtained under optimum conditions of the 30 TC,HTCoC , -40 TE,HTCoC, 0 ∆TCAS,DIFFoC, -50 TE,LTCoC, 0 TSUP,LTCoC, 20 TSUB,LTCoC and 0.01 ṁHTC kg/s.The study revealed that all the factors having interaction with TC[HTC] and TE[HTC] have a great influence on the value of COP.REF[LTC

Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9

Background: One of the main causes of mortality from severe malaria in Plasmodium falciparum infections is cerebral malaria (CM). An important host genetic component determines the susceptibility of an individual to develop CM or to clear the infection and become semi-immune. As such, the identification of genetic loci associated with susceptibility or resistance may serve to modulate disease severity. Methodology The Plasmodium berghei mouse model for experimental cerebral malaria (ECM) reproduces several disease symptoms seen in human CM, and two different phenotypes, a susceptible (FVB/NJ) and a resistant mouse strain (DBA/2J), were examined. Results: FVB/NJ mice died from infection within ten days, whereas DBA/2J mice showed a gender bias: males survived on average nineteen days and females either died early with signs of ECM or survived for up to three weeks. A comparison of brain pathology between FVB/NJ and DBA/2J showed no major differences with regard to brain haemorrhages or the number of parasites and CD3+ cells in the microvasculature. However, significant differences were found in the peripheral blood of infected mice: For example resistant DBA/2J mice had significantly higher numbers of circulating basophils than did FVB/NJ mice on day seven. Analysis of the F2 offspring from a cross of DBA/2J and FVB/NJ mice mapped the genetic locus of the underlying survival trait to chromosome 9 with a Lod score of 4.9. This locus overlaps with two previously identified resistance loci (char1 and pymr) from a blood stage malaria model. Conclusions: Survival best distinguishes malaria infections between FVB/NJ and DBA/2J mice. The importance of char1 and pymr on chromosome 9 in malaria resistance to P. berghei was confirmed. In addition there was an association of basophil numbers with survival

Altered Immune Responses in Rhesus Macaques Co-Infected with SIV and Plasmodium cynomolgi: An Animal Model for Coincident AIDS and Relapsing Malaria

BACKGROUND:Dual epidemics of the malaria parasite Plasmodium and HIV-1 in sub-Saharan Africa and Asia present a significant risk for co-infection in these overlapping endemic regions. Recent studies of HIV/Plasmodium falciparum co-infection have reported significant interactions of these pathogens, including more rapid CD4+ T cell loss, increased viral load, increased immunosuppression, and increased episodes of clinical malaria. Here, we describe a novel rhesus macaque model for co-infection that supports and expands upon findings in human co-infection studies and can be used to identify interactions between these two pathogens. METHODOLOGY/PRINCIPAL FINDINGS:Five rhesus macaques were infected with P. cynomolgi and, following three parasite relapses, with SIV. Compared to macaques infected with SIV alone, co-infected animals had, as a group, decreased survival time and more rapid declines in markers for SIV progression, including peripheral CD4+ T cells and CD4+/CD8+ T cell ratios. The naïve CD4+ T cell pool of the co-infected animals was depleted more rapidly than animals infected with SIV alone. The co-infected animals also failed to generate proliferative responses to parasitemia by CD4+ and CD8+ T cells as well as B cells while also having a less robust anti-parasite and altered anti-SIV antibody response. CONCLUSIONS/SIGNIFICANCE:These data suggest that infection with both SIV and Plasmodium enhances SIV-induced disease progression and impairs the anti-Plasmodium immune response. These data support findings in HIV/Plasmodium co-infection studies. This animal model can be used to further define impacts of lentivirus and Plasmodium co-infection and guide public health and therapeutic interventions

The Impact of Health Insurance on Health Care Provision in Developing Countries

Health insurance, in addition to being a technique for controlling and managing health risks, helps in placing the insured in a position for accessing health care delivery ahead of an illness. This instrument, which has been well utilized in developed economies, is what the National Health Insurance Scheme (NHIS) in Nigeria tries to replicate, albeit ineffectively. This study assesses the impact of the NHIS scheme in promoting access to health care. It identifies a need for all stakeholders to engage in the active promotion of awareness on health insurance as option of health care provisioning. It argues that health insurance can make health care more accessible to a wider segment of the population and help reduce the huge expenditure on health without reducing quality. Ghana Journal of Development Studies Vol. 4 (21) 2007: pp. 49-5