The nature of X-ray spectral variability in Seyfert Galaxies

We use a model-independent technique to investigate the nature of the 2-15 keV X-ray spectral variability in four Seyfert galaxies and distinguish between spectral pivoting and the two-component model for spectral variability. Our analysis reveals conclusively that the softening of the X-ray continuum with increasing flux in MCG -6-30-15 and NGC 3516 is a result of summing two spectral components: a soft varying component (SVC) with spectral shape independent of flux and a constant hard component (HCC). In contrast, the spectral variability in NGC 4051 can be well described by simple pivoting of one component, together with an additional hard constant component. The spectral variability model for NGC 5506 is ambiguous, due to the smaller range of fluxes sampled by the data. We investigate the shape of the hard spectral component in MCG -6-30-15 and find that it appears similar to a pure reflection spectrum, but requires a large reflected fraction (R>3). We briefly discuss physical interpretations of the different modes of spectral variability.Comment: Accepted for publication in MNRAS letter

Very fast X-ray spectral variability in Cygnus X-1: Origin of the hard and soft-state emission components

The way in which the X-ray photon index, {\Gamma}, varies as a function of count rate is a strong diagnostic of the emission processes and emission geometry around accreting compact objects. Here we present the results from a study using a new, and simple, method designed to improve sensitivity to the measurement of the variability of {\Gamma} on very short time-scales. We have measured {\Gamma} in ~2 million spectra, extracted from observations with a variety of different accretion rates and spectral states, on time-scales as short as 16 ms for the high mass X-ray binary Cygnus X-1, and have cross-correlated these measurements with the source count rate. In the soft-state cross-correlation functions (CCFs) we find a positive peak at zero lag, stronger and narrower in the softer observations. Assuming that the X-rays are produced by Compton scattering of soft seed photons by high energy electrons in a corona, these results are consistent with Compton cooling of the corona by seed photons from the inner edge of the accretion disc, the truncation radius of which increases with increasing hardness ratio. The CCFs produced from the hard-state observations, however, show an anti-correlation which is most easily explained by variation in the energy of the electrons in the corona rather than in variation of the seed photon flux. The hard-state CCFs can be decomposed into a narrow anti-correlation at zero lag, which we tentatively associate with the effects of self-Comptonisation of cyclo-synchrotron seed photons in either a hot, optically thin accretion flow or the base of the jet, and a second, asymmetric component which we suggest is produced as a consequence of a lag between the soft and hard X-ray emission. The lag may be caused by a radial temperature/energy gradient in the Comptonising electrons combined with the inward propagation of accretion rate perturbations.Comment: 12 pages, 14 figures; accepted for publication in Monthly Notices of the Royal Astronomical Society, 2013 June

HST emission-line images of nearby 3CR radio galaxies: two photoionization, accretion and feedback modes

We present HST/ACS narrow-band images of a low-z sample of 19 3C radio galaxies to study the H$\alpha$ and [OIII] emissions from the narrow-line region (NLR). Based on nuclear emission line ratios, we divide the sample into High and Low Excitation Galaxies (HEGs and LEGs). We observe different line morphologies, extended line emission on kpc scale, large [OIII]/H$\alpha$ scatter across the galaxies, and a radio-line alignment. In general, HEGs show more prominent emission line properties than LEGs: larger, more disturbed, more luminous, and more massive regions of ionized gas with slightly larger covering factors. We find evidence of correlations between line luminosities and (radio and X-ray) nuclear luminosities. All these results point to a main common origin, the active nucleus, which ionize the surrounding gas. However, the contribution of additional photoionization mechanism (jet shocks and star formation) are needed to account for the different line properties of the two classes. A relationship between the accretion, photoionization and feedback modes emerges from this study. For LEGs (hot-gas accretors), the synchrotron emission from the jet represents the main source of ionizing photons. The lack of cold gas and star formation in their hosts accounts for the moderate ionized-gas masses and sizes. For HEGs (cold-gas accretors), an ionizing continuum from a standard disk and shocks from the powerful jets are the main sources of photoionization, with the contribution from star formation. These components, combined with the large reservoir of cold/dust gas brought from a recent merger, account for the properties of their extended emission-line regions.Comment: accepted for publication on ApJ (22 pages, 12 figures

A jet-dominated model for a broad-band spectral energy distribution of the nearby low-luminosity active galactic nucleus in M94

We have compiled a new multiwavelength spectral energy distribution (SED) for the closest obscured low-ionization emission-line region active galactic nucleus (AGN), NGC 4736, also known as M94. The SED comprises mainly high-resolution (mostly sub-arcsecond, or, at the distance to M94, <23 pc from the nucleus) observations from the literature, archival data, as well as previously unpublished sub-millimetre data from the Plateau de Bure Interferometer (PdBI) and the Combined Array for Research in Millimeter-wave Astronomy, in conjunction with new electronic MultiElement Radio Interferometric Network (e-MERLIN) L-band (1.5 GHz) observations. Thanks to the e-MERLIN resolution and sensitivity, we resolve for the first time a double structure composed of two radio sources separated by ~1 arcsec, previously observed only at higher frequency. We explore this data set, which further includes non-simultaneous data from the Very Large Array, the Gemini telescope, the Hubble Space Telescope and the Chandra X-ray observatory, in terms of an outflow-dominated model. We compare our results with previous trends found for other AGN using the same model (NGC 4051, M81*, M87 and Sgr A*), as well as hard- and quiescent-state X-ray binaries. We find that the nuclear broad-band spectrum of M94 is consistent with a relativistic outflow of low inclination. The findings in this work add to the growing body of evidence that the physics of weakly accreting black holes scales with mass in a rather straightforward fashion.Comment: 18 pages, 7 figure

Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals.

Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease. Serologic studies before the widespread availability of antifungals established current understanding of serologic kinetics and dynamics. Chart histories and complement fixation (CF) titer trends were analyzed for 434 antifungal-treated coccidioidomycosis patients, who were classified by three infectious disease physicians as having either pulmonary uncomplicated coccidioidomycosis (PUC) (n = 248), pulmonary chronic coccidioidomycosis (PCC) (n = 64), disseminated coccidioidomycosis (DC) not including meningitis (n = 86), or coccidioidal meningitis (CM) (n = 36). The median maximal CF titers were 1:4 for PUC patients, 1:24 for PCC patients, 1:128 for DC patients, and 1:32 for CM patients. Approximately 25.4% of PUC patients, 6.2% of PCC patients, 2.3% of DC patients, and 8.3% of CM patients did not develop detectable titers during the study period. Maximal titers developed a mean of 31 days (95% confidence interval [CI], 13 to 50 days) after initial serologic positivity, with no significant differences between groups. Serologic recurrence occurred in 9% of PUC patients, 36% of PCC patients, 50% of DC patients, and 52% of CM patients. Median titer improvement rates were 91 days/dilution for PUC patients, 112 days/dilution for PCC patients, 136 days/dilution for DC patients, and 146 days/dilution for CM patients. Receiver operating characteristic (ROC) analysis revealed that CF testing retains moderate classification value for disseminated infections (area under the curve [AUC], 0.82 [95% CI, 0.78 to 0.87]) and complicated infections (AUC, 0.82 [95% CI, 0.77 to 0.86]). A suitable cutoff value for complicated infections is ≥1:32. Findings update serologic parameters that are relevant for clinical assessment of coccidioidomycosis patients in the triazole era

Tax Optimization in Change of Legal Form from a Sole Entrepreneur to a Limited Company

Diplomová práce se zabývá analýzou změny právní formy podnikání z fyzické osoby na právnickou, konkrétně na společnost s ručením omezeným. Práce je zaměřená na způsob zdanění fyzických a právnických osob, na jednotlivé možnosti přechodu mezi těmito právními formami a zhodnocení záporů a kladů jednotlivých forem podnikání. Cílem práce je sdělit podnikateli výhody a nevýhody zdanění jednotlivých forem podnikání, navrhnout podnikateli změnu právní formy a seznámit ho s jednotlivými kroky, které jsou potřeba při změně právní formy udělat.This thesis analyzes the changes in the legal form of business from individuals to corporate, namely the limited liability company. The work is focused on the method of taxation of natural and legal persons, individual ability to switch between these legal forms and evaluate the pros and cons of various forms of business. The aim is to communicate the business advantages and disadvantages of different forms of taxation of business, entrepreneurs propose a change of legal form and to acquaint him with the steps that are needed to change the legal form to do.

DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides.

One intriguing discovery in modern microbiology is the extensive presence of extracellular DNA (eDNA) within biofilms of various bacterial species. Although several biological functions have been suggested for eDNA, including involvement in biofilm formation, the detailed mechanism of eDNA integration into biofilm architecture is still poorly understood. In the biofilms formed by Myxococcus xanthus, a Gram-negative soil bacterium with complex morphogenesis and social behaviors, DNA was found within both extracted and native extracellular matrices (ECM). Further examination revealed that these eDNA molecules formed well organized structures that were similar in appearance to the organization of exopolysaccharides (EPS) in ECM. Biochemical and image analyses confirmed that eDNA bound to and colocalized with EPS within the ECM of starvation biofilms and fruiting bodies. In addition, ECM containing eDNA exhibited greater physical strength and biological stress resistance compared to DNase I treated ECM. Taken together, these findings demonstrate that DNA interacts with EPS and strengthens biofilm structures in M. xanthus