A note on transience of generalized many-dimensional excited random walks

We consider a variation of the Generalized Excited Random Walk (GERW) in dimension $d\ge 2$ where the lower bound on the drift for excited jumps is time-dependent and decays to zero. We show that if the lower bound decays slower that $n^{-\beta}$ ($n$ is time), for $\beta$ depending on the transitions of the process, the GERW is transient in the direction of the drift.Comment: arXiv admin note: text overlap with arXiv:2201.10666 Add some comments and remarks for a better understanding, besides correcting some typo

Green/Sustainable IT/IS: Concepts and Cases

The current buzz of ‘going green’ has been a recent fad for many companies. But what does ‘going green’ really mean? How did going green get started? Who are the current leaders of sustainable information technology? It is clear that going green is more than a fad and that green technology can provide a number of cost reducing advantages to companies. This paper will explore the history of green IT/IS and sustainability. The paper will discuss current issues with sustainability and offer solutions to those problems. It will also study the current leaders in green IT/IS to serve as an example to companies looking to go green. Finally, the paper will make future recommendations for companies considering increasing their sustainability

Isolated Fetal Ascites Secondary to Persistent Urogenital Sinus

Objective. To present a case of isolated ascites secondary due to urogenital abnormalities (urogenital sinus) without any other prenatal ultrasound marker. Method. A 36-year-old woman with prenatal isolated ascites delivered a female baby, weighing 2.285 g; ascites was drained at birth and the baby underwent several episodes of urinary retention prior to undergoing X-ray investigations. Results. A voiding cystourethrogram revealed a short urogenital sinus: a vesicostomy was performed. A vaginoscopy revealed double vagina with a large posterior vagina. A posterior sagittal anorectal pull-through with genitoplasty was performed at 2 years old with 1-year follow-up. Conclusions. Though rare, a urogenital abnormality is to be suspected in fetal ascites cases with negative viral tests and no cardiac anomalies. The most common ultrasound marker of such abnormalities (fluid filled cavity) may be missing because of complete drainage of urine through the tubes into peritoneum

Immunotherapy in endometrial cancer: new scenarios on the horizon

This extensive review summarizes clinical evidence on immunotherapy and targeted therapy currently available for endometrial cancer (EC) and reports the results of the clinical trials and ongoing studies. The research was carried out collecting preclinical and clinical findings using keywords such as immune environment, tumor infiltrating lymphocytes, programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) expression, immune checkpoint inhibitors, anti-PD-1/PD-L1 antibodies and others’ on PubMed. Finally, we looked for the ongoing immunotherapy trials on ClinicalTrials.gov. EC is the fourth most common malignancy in women in developed countries. Despite medical and surgical treatments, survival has not improved in the last decade and death rates have increased for uterine cancer in women. Therefore, identification of clinically significant prognostic risk factors and formulation of new rational therapeutic regimens have great significance for enhancing the survival rate and improving the outcome in patients with advanced or metastatic disease. The identification of genetic alterations, including somatic mutations and microsatellite instability, and the definition of intracellular signaling pathways alterations that have a major role in in tumorigenesis is leading to the development of new therapeutic options for immunotherapy and targeted therapy

A low-frequency view of mixed-morphology supernova remnant VRO 42.05.01, and its neighbourhood

Context. Mixed-morphology supernova remnants (MM SNRs) are a mysterious class of objects that display thermal X-ray emission within their radio shell. They are an older class of SNRs, and as such are profoundly affected by the environment into which they evolve. VRO 42.05.01 is a MM SNR of puzzling morphology in the direction of the Galactic anticentre. Aims. Low-frequency radio observations of supernova remnants are sensitive to synchrotron electrons accelerated in the shock front. We aim to compare the low-frequency emission to higher frequency observations to understand the environmental and shock acceleration conditions that have given rise to the observed properties of this source. Methods. We present a LOFAR High Band Antenna map centred at 143 MHz of the region of the Galactic plane centred at l = 166°, b = 3.5° at 143 MHz, with a resolution of 148" and an rms noise of 4.4 mJy bm−1. Our map is sensitive to scales as large as 6°. We compared the LOw Frequency ARay (LOFAR) observations to archival higher frequency radio, infrared, and optical data to study the emission properties of the source in different spectral regimes. We did this both for the SNR and for OA 184, an H II region within our field of view. Results. We find that the radio spectral index of VRO 42.05.01 increases at low radio frequencies; i.e. the LOFAR flux is higher than expected from the measured spectral index value at higher radio frequencies. This observed curvature in the low-frequency end of the radio spectrum occurs primarily in the brightest regions of the source, while the fainter regions present a roughly constant power-law behaviour between 143 MHz and 2695 MHz. We favour an explanation for this steepening whereby radiative shocks have high compression ratios and electrons of different energies probe different length scales across the shocks, therefore sampling regions of different compression ratios

Moderate deviations for random field Curie-Weiss models

The random field Curie-Weiss model is derived from the classical Curie-Weiss model by replacing the deterministic global magnetic field by random local magnetic fields. This opens up a new and interestingly rich phase structure. In this setting, we derive moderate deviations principles for the random total magnetization $S_n$, which is the partial sum of (dependent) spins. A typical result is that under appropriate assumptions on the distribution of the local external fields there exist a real number $m$, a positive real number $\lambda$, and a positive integer $k$ such that $(S_n-nm)/n^{\alpha}$ satisfies a moderate deviations principle with speed $n^{1-2k(1-\alpha)}$ and rate function $\lambda x^{2k}/(2k)!$, where $1-1/(2(2k-1)) < \alpha < 1$.Comment: 21 page