The Rise of the Code of Conduct in Japan: Legal Analysis and Prospect

A code of conduct is a set of rules adopted by transnational corporations (“TNCs”) to regulate mainly working conditions and the management of contract factories. TNCs adopted codes of conduct to cope with the rising criticisms from the public in late 1980s and 1990s about unfair labor practices in contract factories in Third World countries. As the globalization of the economy progressed, like American TNCs, Japanese TNCs also transferred their production bases to developing countries like China, Vietnam, Malaysia and Indonesia in search of low wage labor. The development of a code of conduct in Japan is, however, quite different from that of American TNCs, and is very domestic and, in a sense, very “Japanese.” The purpose of this Note is to analyze, from a legal point of view, the development of Japanese codes of conduct and legal risks under Japanese law concerning unfair labor practices in foreign contract factories. Finally, this Note hypothesizes about the direction of the evolution of Japanese codes of conduct

On the bending of rectilinearly anisotropic plates with cracks

This dissertation is concerned with the determination of crack tip stress field in a rectilinearly anisotropic plate subjected to out-of-plane bending

Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes

Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated proteolysis of unassembled subunits. Although N-terminal acetylation- and ubiquitin-mediated proteasomal degradation by the Ac/N-end rule pathway enables selective compensation of excess subunits, it is unclear how widespread this pathway contributes to stoichiometry control. Here we report that dosage compensation depends only partially on the Ac/N-end rule pathway. Our analysis of genetic interactions between 18 subunits and 12 quality control factors in budding yeast demonstrated that multiple E3 ubiquitin ligases and N-acetyltransferases are involved in dosage compensation. We find that N-acetyltransferases-mediated compensation is not simply predictable from N-terminal sequence despite their sequence specificity for N-acetylation. We also find that the compensation of Pop3 and Bet4 is due in large part to a minor N-acetyltransferase NatD. Furthermore, canonical NatD substrates histone H2A/H4 were compensated even in its absence, suggesting N-acetylation-independent stoichiometry control. Our study reveals the complexity and robustness of the stoichiometry control system. Author summary Quality control of multiprotein complexes is important for maintaining homeostasis in cellular systems that are based on functional complexes. Proper stoichiometry of multiprotein complexes is achieved by the balance between protein synthesis and degradation. Recent studies showed that translation efficiency tends to scale with stoichiometry of their subunits. On the other hand, although protein N-terminal acetylation- and ubiquitin-mediated proteolysis pathway is involved in selective degradation of excess subunits, it is unclear how widespread this pathway contributes to stoichiometry control due to the lack of a systematic investigation using endogenous proteins. To better understand the landscape of the stoichiometry control system, we examined genetic interactions between 18 subunits and 12 quality control factors (E3 ubiquitin ligases and N-acetyltransferases), in total 114 combinations. Our data suggest that N-acetyltransferases are partially responsible for stoichiometry control and that N-acetylation-independent pathway is also involved in selective degradation of excess subunits. Therefore, this study reveals the complexity and robustness of the stoichiometry control system. Further dissection of this complexity will help to understand the mechanisms buffering gene expression perturbations and shaping proteome stoichiometry

Quantum magnonics: magnon meets superconducting qubit

The techniques of microwave quantum optics are applied to collective spin excitations in a macroscopic sphere of ferromagnetic insulator. We demonstrate, in the single-magnon limit, strong coupling between a magnetostatic mode in the sphere and a microwave cavity mode. Moreover, we introduce a superconducting qubit in the cavity and couple the qubit with the magnon excitation via the virtual photon excitation. We observe the magnon-vacuum-induced Rabi splitting. The hybrid quantum system enables generation and characterization of non-classical quantum states of magnons.Comment: 10 pages, 6 figure

A benchmark suite with virtualized reality models for supporting tracking evaluation and data set generation

TrakMark 2012, The 3rd International Workshop on Benchmark Test Schemes for AR/MR Geometric Registration and Tracking Method , November 11th 2012, Tsukuba, JapanWe describe a benchmark suite with virtualized reality models for augmented reality and mixed reality. Benchmark datasets created with virtualized reality models do not include any measurement errors. On the other hand, supports for benchmarking processes and for creating datasets are desired by creators and users. The benchmark suite is for supporting tracking evaluation and data set generation. In this paper, we describe a design of the benchmark suite, and show experimental results of benchmarking our tracking method and creating datasets with the benchmark suite

Cases of primary malignant melanoma and melanocytosis of the esophagus observed by magnifying endoscopy : Application to differential diagnosis : case series

Rationale: Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. In contrast, melanocytosis is a benign condition defined as melanocytic proliferation with melanin deposition. PMME is often accompanied by melanocytosis, but differentiating between them is difficult because of their similar appearance. Patient concerns: Here, we reported 3 PMME cases, 2 with melanocytosis. Diagnoses: Magnifying endoscopy revealed characteristic non-uniform pigmented spots along deformed intrapapillary capillary loops (IPCLs) in PMME, while melanocytosis showed fine granule-like or linearly arranged spots and intact IPCLs. Interventions: The patients underwent endoscopic or surgical resection of each lesion. Outcomes: Histologically, magnified images reflected melanocyte growth. For cases 1 and 2, the patients remained disease-free for 61 and 15 months after endoscopic resection, respectively. In case 3, liver metastases developed two months after surgery, and the patient died from liver failure after six months. Lessons: This is the first report describing differences in magnified views of the 2 diseases, which aids a differential diagnosis