1,653 research outputs found
Absorption on horizon-wrapped branes
We compute the absorption cross section of space-time scalars on a static D2
rane, in global coordinates, wrapped on the S^2 of an AdS_2 X S^2 X CY_3
geometry. We discuss its relevance for the construction of the dual quantum
mechanics of Calabi-Yau black holes.Comment: 18 pages, 2 figure
Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomics and metagenomics approach
Pseudo-albinism is a pigmentation disorder observed in flatfish aquaculture with a complex, multi-factor aetiology. We tested the hypothesis that pigmentation abnormalities are an overt signal of more generalised modifications in tissue structure and function, using as a model the Senegalese sole and two important innate immune barriers, the skin and intestine, and their microbiomes. Stereological analyses in pseudo-albino sole revealed a significantly increased mucous cell number in skin (P < 0.001) and a significantly thicker muscle layer and lamina propria in gut (P < 0.001). RNA-seq transcriptome analysis of the skin and gut identified 573 differentially expressed transcripts (DETs, FDR < 0.05) between pseudo-albino and pigmented soles (one pool/tissue from 4 individuals/phenotype). DETs were mainly linked to pigment production, skin structure and regeneration and smooth muscle contraction. The microbiome (16 S rRNA analysis) was highly diverse in pigmented and pseudo-albino skin but in gut had low complexity and diverged between the two pigmentation phenotypes. Quantitative PCR revealed significantly lower loads of Mycoplasma (P < 0.05) and Vibrio bacteria (P < 0.01) in pseudo-albino compared to the control. The study revealed that pseudo-albinism in addition to pigmentation changes was associated with generalised changes in the skin and gut structure and a modification in the gut microbiome.Agência financiadora
H2020 European Funds MSCA-RISE project
691102
Portuguese national funds from FCT - Foundation for Science and Technology
UID/Multi/04326/2019
Portuguese national funds from the operational programme CRESC Algarve 2020
EMBRC. PT ALG-01-0145-FEDER-022121
Portuguese national funds from the operational programme COMPETE 2020
EMBRC. PT ALG-01-0145-FEDER-022121
European Union (EU)
654008
Fundacao para a Ciencia e a Tecnologia (FCT)
SFRH/BPD/84033/2012
Portuguese Institute for Employment and Vocational Training
0068/ET/18info:eu-repo/semantics/publishedVersio
Association of child neurodevelopmental or behavioural problems with maternal unemployment in a population-based birth cohort
PurposeTo estimate associations between suspected or diagnosed neurodevelopmental or behavioural problems in 7-year-old children and maternal unemployment at child age 7 and 10, in a Portuguese birth cohort.MethodsWe evaluated 5754 mothers and their children of the population-based birth cohort Generation XXI in Porto, Portugal. Data on suspected and diagnosed child neurodevelopmental and behavioural problems (exposures)-learning, attention and language problems, externalising behaviours, developmental delay, autism spectrum disorders, and other neurodevelopmental problems-were retrieved at 7 years of age by interviewing caregivers. Maternal employment status (outcome) was collected at the 7- and 10-year follow-up waves. Robust Poisson regression models were used to estimate associations.ResultsAfter adjustment for maternal and household characteristics, women were more likely to be unemployed at child age 10 if the child had, up to age 7, any of the following suspected problems: an autism spectrum disorder (PR = 1.73; 95% CI 1.07, 2.79), developmental delay (PR = 1.58; 95% CI 1.20, 2.06), externalising behaviours (PR = 1.29; 95% CI 1.11, 1.50) or learning problems (PR = 1.26; 95% CI 1.07, 1.48). When the exposure was restricted to clinically diagnosed disorders, the magnitude of associations remained similar but estimates were less precise. Associations with unemployment were stronger at child age 10 (prospective analyses), than at child age 7 (cross-sectional).ConclusionHaving a child with learning, developmental or behavioural problems, or an autism spectrum disorder up to age 7 was associated with maternal unemployment three years later, even in a less affluent European economy where the dual-earner family structure is often necessary to make ends meet.This study was funded by European Regional Development Fund (ERDF) through the Operational Programme Competitiveness and Internationalization; national funding from Foundation for Science and Technology (FCT)-Portuguese Ministry of Science, Technology and Higher Education under the projects 'STEPACHE-Raizes pediatricas da resposta ampliada a dor: das influencias contextuais a estratificacao do risco' (POCI- 01- 0145FEDER-029087) [Ref. FCT PTDC/SAUEPI/29087/2017], 'HIneC: Quando se revelam as desigualdades em saude?' (POCI-01-0145FEDER-029567) [Ref. FCT PTDC/SAU-PUB/29567/2017]; Epidemiology Research Unit-Instituto de Saude Publica, Universidade do Porto (EPIUnit) (POCI-01-0145-FEDER-006862; UID/DTP/04750/2019); Administracao Regional de Saude Norte (Regional Department of Ministry of Health) and Fundacao Calouste Gulbenkian; EEA Grants through the Work-life Balance and Gender Equality program operated by CIG (SGS3A2); ERDF, through the North Regional Operational Program in the framework of the project HEALTHUNORTE: Setting-up biobanks and regenerative medicine strategies to boost research in cardiovascular, musculoskeletal, neurological, oncological, immunological and infectious diseases (NORTE-01-0145FEDER-000039); PhD grant (Joana Amaro) co-funded by the FCT and the Human Capital Operating Program of the European Social Fund (POPH/ FSE Program) [PD/BD/128009/2016]; research grant from FOREUM Foundation for Research in Rheumatology (Career Research Grant). This study was based upon work from COST Action CA16216 (OMEGA-NET), supported by COST (European Cooperation in Science and Technology)
5D gravitational waves from complexified black rings
In this paper we construct and briefly study the 5D time-dependent solutions
of general relativity obtained via double analytic continuation of the black
hole (Myers-Perry) and of the black ring solutions with a double
(Pomeransky-Senkov) and a single rotation (Emparan-Reall). The new solutions
take the form of a generalized Einstein-Rosen cosmology representing
gravitational waves propagating in a closed universe. In this context the
rotation parameters of the rings can be interpreted as the extra wave
polarizations, while it is interesting to state that the waves obtained from
Myers-Perry Black holes exhibit an extra boost-rotational symmetry in higher
dimensions which signals their better behavior at null infinity. The analogue
to the C-energy is analyzed.Comment: 18 pages, 4 figures. References added, introduction and conclusions
are amended, some issues related to singularity structure and symmetries are
discussed. Matches the print version to appear in JHE
Impact of antenna correlation on the performance of partial relay selection
Antenna correlation is generally viewed as an obstacle to realize the desired performance of a wireless system. In this article, we investigate the performance of partial relay selection in the presence of antenna correlation. We consider both channel state information (csi)-assisted and fixed gain amplify-and-forward (AF) relay schemes. The source and the destination are equipped with multiple antennas communicating via the best first hop signal-to-noise ratio (SNR) relay. We derived the closed form expression for outage probability, average symbol error rate (SER) for both schemes. Further, an exact expression is derived for the ergodic capacity in the csi-assisted relay case and an approximated expression is considered for the fixed gain case. Moreover, we provide simple asymptotic results and show that the diversity order of the system remains unchanged with the effect of antenna correlation for both types of relay schemes
Molecular analyses reveal the occurrence of three new sympatric lineages of velvet worms (Onychophora: Peripatidae) in the eastern Amazon basin
Analysis of tectonic-controlled fluvial morphology and sedimentary processes of the western Amazon Basin: an approach using satellite images and digital elevation model
Helicobacter pylori and anemia: a community-based cross-sectional study among adults in Southern Brazil
Thinking dispositions for teaching : enabling and supporting resilience in context
Preparing pre-teachers for an increasingly challenging teaching profession is a complex work and requires teacher educators to engage in the careful design of both programmes and professional learning opportunities. This chapter explores how an explicit focus on thinking dispositions that enable effective teaching are developed in a Master of Teaching (Secondary) programme. This programme, delivered on-site at a secondary school, included carefully constructed teaching opportunities to support development of thinking dispositions. Ways of thinking and the impact they have on feelings, actions and beliefs will be examined along with how the implementation of our thinking dispositions framework supports the development of resilience in challenging teaching and learning contexts
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