195 research outputs found

    Electromagnetic Pulse Sounding for Surveying Underground Water

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    This project supported in part by the Office of Water Resources Research U. S. Department of the Interior Washington, D. C. under Project B-028-OHIOA number of approaches have been explored for measuring the water content of soil electrically. In contrast with traditional measurements, which utilize electric currents at DC or at specific frequencies, our techniques have been based on the transmission and reflection of sharp, regularly repeated pulses. Such pulse measurements can be shown to be equivalent to measuring the electrical properties at all frequencies in a very wide band, and therefore the possibility of extracting the desired information is much greater than with single-frequency measurements. Because the information content of the signal is great, data processing can be used to extract those features which relate most directly to moisture content and reject those which appear to depend more on soil inhomogenieties. For example, it was found that the attenuation in the frequency band of approximately 10 to 20 MHz had a much higher correlation with soil moisture than that in other frequency bands for the actual field conditions under which our measurements were made. This information content increase is obtained by means of sophisticated research equipment. The measurements reported herein were made and processed under real-time computer control. They include the signal scattered from known buried targets, transmission measurements through the ground, and the measurement of reflections in a coaxial test cell, all with pulses containing very wide frequency bands. The results are encouraging in that definite correlations with moisture were found. Unfortunately the one-year time limitation of this effort, much of it spent in instrumentation development, was insufficient to allow testing these correlations quantitatively over extended time periods or in a variety of locations. Thus the techniques must be evaluated at present as promising, but not fully proven. It should be noted that, while the research system to obtain this information is complex, field equipment based on these techniques need not be unduly complicated or expensive. Once the features relating to moisture content under the greatest variety of field conditions are identified, means for extracting this information more simply should be devised. This is proposed as the objective for continuation of this effort.Summary -- Introduction -- 1. The Measuring System -- 2. Data Processing -- 3. Underground Moisture Content Monitoring by Measurement of Buried Target Signatures -- 4. Sampled Moisture Conditions -- 5. Underground Propagation Experiment -- 6. Reflection Measurements on Soil Samples in a Vertical Coaxial Test Cell -- 7. Propagation Calculations -- Conclusions -- Recommendations -- References -- Appendix I - Transmission Measurements using a Buried Antenn

    Avoiding or restricting defectors in public goods games?

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    When creating a public good, strategies or mechanisms are required to handle defectors. We first show mathematically and numerically that prior agreements with posterior compensations provide a strategic solution that leads to substantial levels of cooperation in the context of public goods games, results that are corroborated by available experimental data. Notwithstanding this success, one cannot, as with other approaches, fully exclude the presence of defectors, raising the question of how they can be dealt with to avoid the demise of the common good. We show that both avoiding creation of the common good, whenever full agreement is not reached, and limiting the benefit that disagreeing defectors can acquire, using costly restriction mechanisms, are relevant choices. Nonetheless, restriction mechanisms are found the more favourable, especially in larger group interactions. Given decreasing restriction costs, introducing restraining measures to cope with public goods free-riding issues is the ultimate advantageous solution for all participants, rather than avoiding its creation.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Jejunogastric intussusception presented with hematemesis: a case presentation and review of the literature

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    BACKGROUND: Jejunogastric intussusception (JGI) is a rare but potentially very serious complication of gastrectomy or gastrojejunostomy. To avoid mortality early diagnosis and prompt surgical intervention is mandatory. CASE PRESENTATION: A young man presented with epigastric pain and bilous vomiting followed by hematemesis,10 years after vagotomy and gastrojejunostomy for a bleeding duodenal ulcer. Emergency endoscopy showed JGI and the CT scan of the abdomen was compatible with this diagnosis. At laparotomy a retrograde type II, JGI was confirmed and managed by reduction of JGI without intestinal resection. Postoperative recovery was uneventful. CONCLUSIONS: JGI is a rare condition and less than 200 cases have been published since its first description in 1914. The clinical picture is almost diagnostic. Endoscopy performed by someone familiar with this rare entity is certainly diagnostic and CT-Scan of the abdomen could also help. There is no medical treatment for acute JGI and the correct treatment is surgical intervention as soon as possible

    Relative influence of shredders and fungi on leaf litter decomposition along a river altitudinal gradient

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    We compared autumn decomposition rates of European alder leaves at four sites along the Lasset–Hers River system, southern France, to test whether changes in litter decomposition rates from upstream (1,300 m elevation) to downstream (690 m) could be attributed to temperature-driven differences in microbial growth, shredder activity, or composition of the shredder community. Alder leaves lost 75–87% of original mass in 57 days, of which 46–67% could be attributed to microbial metabolism and 8–29% to shredder activity, with no trend along the river. Mass loss rates in both fine-mesh (excluding shredders) and coarse-mesh (including shredders) bags were faster at warm, downstream sites (mean daily temperature 7–8Β°C) than upstream (mean 1–2Β°C), but the differ- ence disappeared when rates were expressed in heat units to remove the temperature effect. Mycelial biomass did not correlate with mass loss rates. Faster mass loss rates upstream, after temperature correction, evidently arise from more efficient shredding by Nemourid stoneflies than by the Leuctra-dominated assemblage downstream. The influence of water temperature on decomposition rate is therefore expressed both directly, through microbial metabolism, and indirectly, through the structure of shredder commu- nities. These influences are evident even in cold water where temperature variation is small

    Fragilities Caused by Dosage Imbalance in Regulation of the Budding Yeast Cell Cycle

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    Cells can maintain their functions despite fluctuations in intracellular parameters, such as protein activities and gene expression levels. This commonly observed biological property of cells is called robustness. On the other hand, these parameters have different limitations, each reflecting the property of the subsystem containing the parameter. The budding yeast cell cycle is quite fragile upon overexpression of CDC14, but is robust upon overexpression of ESP1. The gene products of both CDC14 and ESP1 are regulated by 1∢1 binding with their inhibitors (Net1 and Pds1), and a mathematical model predicts the extreme fragility of the cell cycle upon overexpression of CDC14 and ESP1 caused by dosage imbalance between these genes. However, it has not been experimentally shown that dosage imbalance causes fragility of the cell cycle. In this study, we measured the quantitative genetic interactions of these genes by performing combinatorial β€œgenetic tug-of-war” experiments. We first showed experimental evidence that dosage imbalance between CDC14 and NET1 causes fragility. We also showed that fragility arising from dosage imbalance between ESP1 and PDS1 is masked by CDH1 and CLB2. The masking function of CLB2 was stabilization of Pds1 by its phosphorylation. We finally modified Chen's model according to our findings. We thus propose that dosage imbalance causes fragility in biological systems

    Hmgcr in the Corpus Allatum Controls Sexual Dimorphism of Locomotor Activity and Body Size via the Insulin Pathway in Drosophila

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    The insulin signaling pathway has been implicated in several physiological and developmental processes. In mammals, it controls expression of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGCR), a key enzyme in cholesterol biosynthesis. In insects, which can not synthesize cholesterol de novo, the HMGCR is implicated in the biosynthesis of juvenile hormone (JH). However, the link between the insulin pathway and JH has not been established. In Drosophila, mutations in the insulin receptor (InR) decrease the rate of JH synthesis. It is also known that both the insulin pathway and JH play a role in the control of sexual dimorphism in locomotor activity. In studies here, to demonstrate that the insulin pathway and HMGCR are functionally linked in Drosophila, we first show that hmgcr mutation also disrupts the sexual dimorphism. Similarly to the InR, HMGCR is expressed in the corpus allatum (ca), which is the gland where JH biosynthesis occurs. Two p[hmgcr-GAL4] lines were therefore generated where RNAi was targeted specifically against the HMGCR or the InR in the ca. We found that RNAi-HMGCR blocked HMGCR expression, while the RNAi-InR blocked both InR and HMGCR expression. Each RNAi caused disruption of sexual dimorphism and produced dwarf flies at specific rearing temperatures. These results provide evidence: (i) that HMGCR expression is controlled by the InR and (ii) that InR and HMGCR specifically in the ca, are involved in the control of body size and sexual dimorphism of locomotor activity

    Cholesterol Metabolism Is Required for Intracellular Hedgehog Signal Transduction In Vivo

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    We describe the rudolph mouse, a mutant with striking defects in both central nervous system and skeletal development. Rudolph is an allele of the cholesterol biosynthetic enzyme, hydroxysteroid (17-beta) dehydrogenase 7, which is an intriguing finding given the recent implication of oxysterols in mediating intracellular Hedgehog (Hh) signaling. We see an abnormal sterol profile and decreased Hh target gene induction in the rudolph mutant, both in vivo and in vitro. Reduced Hh signaling has been proposed to contribute to the phenotypes of congenital diseases of cholesterol metabolism. Recent in vitro and pharmacological data also indicate a requirement for intracellular cholesterol synthesis for proper regulation of Hh activity via Smoothened. The data presented here are the first in vivo genetic evidence supporting both of these hypotheses, revealing a role for embryonic cholesterol metabolism in both CNS development and normal Hh signaling
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