Empirische Shortcuts:Studentische Forschungsprojekte in der Methodenlehre

Die empirische Bildungsforschung hat in den letzten Jahren einen nachhaltigen quantitativen und qualitativen Aufschwung genommen. Erziehungswissenschaftliche Forschung erschöpft sich jedoch nicht im M&E des schulischen Lernstands im nationalen und internationalen Vergleich und seiner Ursachen sondern umfasst ein weites Feld an Fragestellungen aus unterschiedlichsten Bereichen. Dies muss den Studierenden, neben den methodischen Modellen und Instrumentarien exemplarisch vermittelt werden. Das ideale didaktische Modell hierfür ist zweifellos ein von den Studierenden selbst konzipiertes und durchgeführtes Forschungsprojekt, wie es seit Jahren im Programmbereich „Empirische Pädagogik“ des Instituts für Erziehungswissenschaft der WWU Münster praktiziert. Dadurch werden den Studierenden Dimensionen eröffnet, die im Zeitalter von Modularisierung, OECD-Statistiken und Ressourcenverknappung sich zunehmend verengen. Die damit verbundenen Impulse und Erfahrungsgewinne sind in eine Belebung und Bereicherung des Studiums

Ultrafast laser inscribed integrated photonics: material science to device development

Detailed studies of intense light – material interactions has led to new insights into fs laser induced refractive index change in a range of glass types. This body of knowledge enables the development of advanced processing methodologies, resulting in novel planar and 3D guided wave devices. We will review the chemistry and morphology associated with fs laser induced refractive index change in multi-component glasses such as ZBLAN, phosphates and silicates, and discuss how these material changes inform our research programs developing a range of active and passive lightwave systems.S. Gross, T. D. Meany, A. Arriola, C. Miese, R. J. Williams, Y. Duan, Q. Liu, I. Spaleniak, M. Ams, P. Dekker, N. Jovanovic, A. Fuerbach, M. Ireland, M. J. Steel, D. G. Lancaster, H. Ebendorff Heidepriem, T. M. Monro, and M. J. Withfor

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

Adult education and trade unionism in North-East Brazil A study of a practice of popular education

2 volsSIGLEAvailable from British Library Document Supply Centre- DSC:D85787 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Functional analytic continuation techniques with applications in field theory

SIGLELD:3630.84(DIAS-STP--82-14). / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Solar heating of the Sportsco pool at Dublin Demonstration project

Final reportAvailable from British Library Document Supply Centre- DSC:3828.4F(EUR--11063-EN)(microfiche) / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

The Impact of Benevolence in Computational Trust

Trust is a construct of paramount importance in society. Accordingly, computational trust is evolving fast in order to allow trust in artificial societies. Despite the advances in this research field, most computational trust approaches evaluate trust by estimating the trustworthiness of the agents under evaluation (the trustees), without however distinguishing between the different dimensions of trustworthiness, such as ability and benevolence. In this paper, we propose different techniques to extract the ability of the trustee in the task at hand and to infer the benevolence of the trustee toward the truster when the trust judgment is made. Moreover, we propose to dynamically change the relative importance and impact of both ability and benevolence on the perceived trustworthiness of the trustee, taking into consideration the development of the relationship between the truster and the trustee and the disposition of the truster in the specific situation. Finally, we set an experimental scenario to evaluate our approach. The results obtained from these experiments show that the proposed techniques significantly improve the reliability of the estimation of the trustworthiness of agents. © 2013 Springer-Verlag