4,158 research outputs found
Mobile Healthcare System for Preventive of Metabolic Syndrome
Recently, metabolic syndrome affects a great number of people in Japan. Glycemic control can delay the onset and slow the progression of vascular complications. Lifestyle modification
including weight reduction can contribute significantly to
glycemic control. This paper describes the mobile application of the healthcare support system for metabolic patients
Impurity-Induced Electronic Nematic State in Iron-Pnictide Superconductors
We propose that impurity-induced electronic nematic state is realized above
the orthorhombic structure transition temperature in iron-pnictide
superconductors. In the presence of strong orbital fluctuations near , it
is theoretically revealed that a single impurity induces non-local orbital
order with -symmetry, consistently with recent STM/STS measurements. Each
impurity-induced orbital order aligns along a-axis by applying tiny
uniaxial pressure along b-axis. In this impurity-induced nematic phase, the
resistivity shows sizable in-plane anisotropy () even
above , actually observed in various "detwinned" samples. The present
study indicates the existence of strong orbital fluctuations in iron-pnictide
superconductors.Comment: 5 pages, 4 figure
Some Theoretical Aspects on Optimal Toll-Rate and Scale of Urban Expressway
In this paper, the optimal toll-rate and scale of urban expressway is discussed economically. The criterion used is the total surplus of expressway, which is defined as the sum of consumer's surplus of expressway users and producer's surplus on the side of expressway administrator. The total surplus is equivalent to the difference of the value of total saved travel times of expressway users and the total cost required to construct and administrate expressway systems. The flow-dependent travel times is assumed, and traffic demand is induced through equilibrium method. On the other hand, for the management of expressway to be capable, the accounting condition that the fare revenue must repay the total cost should be satisfied. Under this accounting condition, the optimal rate and scale which maximize the total surplus are requested, and their properties are examined. The analysis is practiced for both caces of flowindependent cost function and flow-dependent cost function. One remarkable result is that the maximum feasible scale under the accounting condition does not privide a maximum for total surplus
New In-Situ Characterization Technique of Active Materials in Batteries: Electrochemical Acoustic Emission Method
Regulation of glucose metabolism by central insulin action
Insulin has been known to act on the hypothalamus, in particular the arcuate nucleus, in the central nervous system. Such central insulin action is not only involved in the regulation of energy metabolism via the regulation of food intake and heat production, but also plays an important role in glucose metabolism by regulating hepatic glucose production and glucose uptake by skeletal muscles. Studies on the intracerebroventricular administration of PI-3K inhibitors or sulfonylureas have demonstrated that hyperpolarization of agouti-related protein neurons induced by the activation of PI-3K signaling/KATP channels in the hypothalamic arcuate nucleus plays an important role in the suppression of hepatic glucose production mediated by central insulin action. Cutting of the vagus nerve overrides the suppression of hepatic glucose production by intracerebroventricular insulin administration, which suggests the involvement of autonomic nerves in central insulin action in the liver. The central insulin action-mediated suppression of hepatic glucose production is associated with decreased gene expression of enzymes involved in hepatic gluconeogenesis, and both increased interleukin-6 expression in hepatic non-parenchymal cells induced by central insulin action and associated activation of hepatic STAT3 play an important role in the suppression of gene expression of hepatic gluconeogenesis-related enzymes. In animal models of obesity and insulin resistance, the central insulin action-mediated hepatic glucose production control mechanism is impaired in both the hypothalamus and liver. Increased hepatic gluconeogenesis in obesity and type-2 diabetes has been attributed to impaired hepatic insulin signaling and increased expression of enzymes involved in hepatic gluconeogenesis due to hyperglycemia, but may also be partially attributed to the impairment of the central insulin action-mediated suppression of hepatic gluconeogenesis.Biomedical Reviews 2011; 22: 31-39
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