The significance of seniority for women managers’ interpretations of organizational restructuring

This paper examines the impact of restructuring within the transport and logistics sector on women managers working at senior and less senior (middle/junior management) levels of the organization. The majority of women experienced increased performance pressures and heavier workloads as well as an increase in working hours. At the same time, there were pressures to work at home (i.e. week-ends and evenings) and reduced opportunities to work from home (i.e. during normal office hours). Management level emerged as an important factor in how these changes were interpreted. Senior managers perceived more positive outcomes in terms of increased motivation and loyalty. Despite a longer working week, they were less likely to report low morale as an outcome from long hours. In fact, irrespective of management level, women working shorter hours were more likely to report low morale as an outcome. Results are discussed in relation to literature on restructuring and careers, in terms of perceptual framing and in relation to different levels of investment in the organization

Human C4orf14 interacts with the mitochondrial nucleoid and is involved in the biogenesis of the small mitochondrial ribosomal subunit.

The bacterial homologue of C4orf14, YqeH, has been linked to assembly of the small ribosomal subunit. Here, recombinant C4orf14 isolated from human cells, co-purified with the small, 28S subunit of the mitochondrial ribosome and the endogenous protein co-fractionated with the 28S subunit in sucrose gradients. Gene silencing of C4orf14 specifically affected components of the small subunit, leading to decreased protein synthesis in the organelle. The GTPase of C4orf14 was critical to its interaction with the 28S subunit, as was GTP. Therefore, we propose that C4orf14, with bound GTP, binds to components of the 28S subunit facilitating its assembly, and GTP hydrolysis acts as the release mechanism. C4orf14 was also found to be associated with human mitochondrial nucleoids, and C4orf14 gene silencing caused mitochondrial DNA depletion. In vitro C4orf14 is capable of binding to DNA. The association of C4orf14 with mitochondrial translation factors and the mitochondrial nucleoid suggests that the 28S subunit is assembled at the mitochondrial nucleoid, enabling the direct transfer of messenger RNA from the nucleoid to the ribosome in the organelle.Medical Research Council (MRC); Biotechnology and Biological Sciences Research Council (BBSRC); European Union; Academy of Finland (to H.M.C.). Funding for open access charge: MRC

The mechanisms underpinning the effects of self-control exertion on subsequent physical performance: a meta-analysis

Prior self-control exertion is consistently reported to cause decrements in subsequent physical performance. However, research into the explanatory mechanisms underpinning the effect is limited and has not been assessed under a meta-analytical lens. Therefore, the present study reports a meta-analysis examining the effects of self-control exertion on subsequent physical performance, as well as the mechanisms underpinning the effect. A systematic search of relevant databases was conducted to identify studies that utilized the sequential task paradigm, involving self-control manipulations lasting 30 minutes or less, and examined an aspect of physical performance. Random effects meta-analysis demonstrated that the prior exertion of self-control resulted in a statistically significant medium sized negative effect of prior self-control exertion on subsequent physical performance (g = −0.55). Further analysis revealed a small increase in initial perceptions of pain (g = 0.18) and a medium sized reduction in self-efficacy (g = −0.48), while motivation and RPE were unaffected following the exertion of self-control. The present study provides a novel insight into the mechanisms underpinning the effects of prior self-control exertion on subsequent physical performance. Initial perceptions of pain and self-efficacy appear important mechanisms and thus could be targeted in future interventions aimed at attenuating the effects of self-control exertion to enhance subsequent physical performance

Self-control exertion and goal priming: effects on time-to-exhaustion cycling performance

Interventions to attenuate the negative effects of prior self-control exertion on physical performance are limited. The current study had three primary objectives: a) to investigate whether prior self-control exertion reduces subsequent performance on a time-to-exhaustion (TTE) cycling task, b) to investigate if goal priming attenuated the detrimental effects of self-control depletion on subsequent physical performance, c) to examine the potential for any observed performance decrements to be explained by changes in perceptions of pain and motivation. Fourteen recreationally active males (23 ± 3 years) completed three TTE cycling tasks at 80% V̇O2 peak on an electromagnetically braked cycle ergometer. Prior to each TTE cycling task, participants completed a self-control depletion condition (incongruent Stroop task) or a non-self-control depletion condition (congruent Stroop task) for 4 min. During the TTE cycling task, participants were asked to watch a video on the screen in front of them. During this video, participants were exposed to a goal priming sequence (intervention condition) or a random letter sequence (control condition). The participants’ TTE cycling task performance time, subjective measures, and cycling cadence were recorded every 3 min during the TTE task. A one-way repeated-measures ANOVA revealed that there was no significant difference in TTE cycling task performance between the experimental conditions (p = 0.28). Furthermore, there were no significant changes in perceptions of pain (p = 0.36) or motivation (p = 0.21). The findings indicate that prior self-control exertion did not negatively affect subsequent TTE cycling task performance. In addition, goal priming does not influence the effects of initial self-control exertion on subsequent physical task performance

Automated Morphological Classification of SDSS Red Sequence Galaxies

(abridged) In the last decade, the advent of enormous galaxy surveys has motivated the development of automated morphological classification schemes to deal with large data volumes. Existing automated schemes can successfully distinguish between early and late type galaxies and identify merger candidates, but are inadequate for studying detailed morphologies of red sequence galaxies. To fill this need, we present a new automated classification scheme that focuses on making finer distinctions between early types roughly corresponding to Hubble types E, S0, and Sa. We visually classify a sample of 984 non-starforming SDSS galaxies with apparent sizes >14". We then develop an automated method to closely reproduce the visual classifications, which both provides a check on the visual results and makes it possible to extend morphological analysis to much larger samples. We visually classify the galaxies into three bulge classes (BC) by the shape of the light profile in the outer regions: discs have sharp edges and bulges do not, while some galaxies are intermediate. We separately identify galaxies with features: spiral arms, bars, clumps, rings, and dust. We find general agreement between BC and the bulge fraction B/T measured by the galaxy modeling package GIM2D, but many visual discs have B/T>0.5. Three additional automated parameters -- smoothness, axis ratio, and concentration -- can identify many of these high-B/T discs to yield automated classifications that agree ~70% with the visual classifications (>90% within one BC). Both methods are used to study the bulge vs. disc frequency as a function of four measures of galaxy 'size': luminosity, stellar mass, velocity dispersion, and radius. All size indicators show a fall in disc fraction and a rise in bulge fraction among larger galaxies.Comment: 24 pages, 20 figures, MNRAS accepte

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

Mitochondrial ribosomes and translation factors co-purify with mitochondrial nucleoids of human cells, based on affinity protein purification of tagged mitochondrial DNA binding proteins. Among the most frequently identified proteins were ATAD3 and prohibitin, which have been identified previously as nucleoid components, using a variety of methods. Both proteins are demonstrated to be required for mitochondrial protein synthesis in human cultured cells, and the major binding partner of ATAD3 is the mitochondrial ribosome. Altered ATAD3 expression also perturbs mtDNA maintenance and replication. These findings suggest an intimate association between nucleoids and the machinery of protein synthesis in mitochondria. ATAD3 and prohibitin are tightly associated with the mitochondrial membranes and so we propose that they support nucleic acid complexes at the inner membrane of the mitochondrion.Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC); Intramural program of the National Institutes of Health, National Heart, Lung and Blood Institute (to K.N.); Academy of Finland (to H.M.C.). Funding for open access charge: MRC

Internet-based monitoring of influenza-like illness (ILI) in the general population of the Netherlands during the 2003–2004 influenza season

BACKGROUND: An internet-based survey of influenza-like illness (ILI) – the Great Influenza Survey or GIS – was launched in the Netherlands in the 2003–2004 influenza season. The aim of the present study was to validate the representativeness of the GIS population and to compare the GIS data with the official ILI data obtained by Dutch GPs participating in the Dutch Sentinel Practice Network. METHOD: Direct mailings to schools and universities, and repeated interviews on television and radio, and in newspapers were used to kindle the enthusiasm of a broad section of the public for GIS. Strict symptomatic criteria for ILI were formulated with the assistance of expert institutes and only participants who responded at least five times to weekly e-mails asking them about possible ILI symptoms were included in the survey. Validation of GIS was done at different levels: 1) some key demographic (age distribution) and public health statistics (prevalence of asthma and diabetes, and influenza vaccination rates) for the Dutch population were compared with corresponding figures calculated from GIS; 2) the ILI rates in GIS were compared with the ILI consultation rates reported by GPs participating in the Dutch Sentinel Practice Network. RESULTS: 13,300 persons (53% of total responders), replied at least five times to weekly e-mails and were included in the survey. As expected, there was a marked under-representation of the age groups 0–10 years and 81->90 years in the GIS population, although the similarities were remarkable for most other age groups, albeit that the age groups between 21 and 70 years were slightly overrepresented. There were striking similarities between GIS and the Dutch population with regard to the prevalence of asthma (6.4% vs. 6.9%) and the influenza vaccination rates, and to a lesser degree for diabetes (2.4% vs. 3.5%). The vaccination rates in patients with asthma or diabetes, and persons older than 65 years were 68%, 85%, and 85% respectively in GIS, while the corresponding percentages in the Dutch population were 73%, 85% and 87%. There was also a marked similarity between the seasonal course of ILI measured by GIS and the GPs. Although the ILI rate in GIS was about 10 times higher, the curves followed an almost similar pattern, with peak incidences occurring in the same week. CONCLUSION: The current study demonstrates that recruitment of a high number of persons willing to participate in on-line health surveillance is feasible. The information gathered proved to be reliable, as it paralleled the information obtained via an undisputed route. We believe that the interactive nature of GIS and the appealing subject were keys to its success

Galaxy Luminosity Functions to z~1: DEEP2 vs. COMBO-17 and Implications for Red Galaxy Formation

The DEEP2 and COMBO-17 surveys are used to study the evolution of the luminosity function of red and blue galaxies to $z \sim 1$. Schechter function fits show that, since $z = 1$, $M^*_B$ dims by $\sim$ 1.3 mag per unit redshift for both color classes, $\phi^*$ of blue galaxies shows little change, while $\phi^*$ for red galaxies has formally nearly quadrupled. At face value, the number density of blue galaxies has remained roughly constant since $z = 1$, whereas that of red galaxies has been rising. Luminosity densities support both conclusions, but we note that most red-galaxy evolution occurs between our data and local surveys and in our highest redshift bin, where the data are weakest. We discuss the implications of having most red galaxies emerge after $z = 1$ from precursors among the blue population, taking into account the properties of local and distant E/S0s. We suggest a ``mixed'' scenario in which some blue galaxies have their star-formation quenched in gas-rich mergers, migrate to the red sequence with a variety of masses, and merge further on the red sequence in one or more purely stellar mergers. E/S0s of a given mass today will have formed via different routes, in a manner that may help to explain the fundamental plane and other local scaling laws.Comment: Submitted to ApJ. 73 pages, 12 figures. Part II of a two-paper series. The entire paper is available as a single postscript file at: http://www.ucolick.org/~cnaw/paper2_submitted.ps.g