Minimality and Turkish Relative Clauses

Turkish relative clauses display a subject/non-subject asymmetry. The subject relative (SR) is licensed for relativization from [Spec, TP]. Whereas the non-subject relative (NSR) is never acceptable for subject relativization, the SR is licensed in clauses where there is no external argument, and when relativizing a non-subject in clauses where the subject is non-specific. Within the framework of the Minimalist Program, Turkish RCs are explained in terms of satisfaction of the EPP of T by a D feature and Minimality effects. As long as no nominal expression intervenes between the relative head and [Spec, TP], the SR is licensed. The SR, then, can be used as a diagnostic for movement through TP. Minimality effects are incurred when there is an intervening nominal between T° and the RC head, and the SR becomes unacceptable. The proposal is that in Turkish, specific nominals, +human nominals, and Experiencers of psych verbs all contain a DP projection. Non-specifics are NPs which cannot satisfy the EPP. NP subjects cannot move to [Spec, TP], and thus permit the SR form for relativization of non-subjects. NPs create intervention effects, as does PRO, with the exception of subject control PRO which is perhaps a trace of movement. Scrambling ameliorates intervention effects. Once scrambled, expressions are frozen but remain porous for movement of a subconstituent. Differences between inherent and structural Case are suggested with structural case assignment limited to DPs and in a Spec-Head configuration. Structurally case-marked DPs are barred from moving to case-assigning positions unless there is a morphological match. Further proposals include structures for verb classes, including Psych verbs, and structures for infinitivals and +human DPs. Contrastive focus is briefly addressed. Though superficially complex, relativization in Turkish can be accounted for with a minimum of technology. The suggestions here have implications for the theory of the EPP, Case, its assignment and interface conditions, feature satisfaction, and movement

Subfatin concentration decreases in acute coronary syndrome

We investigated the association of serum subfatin concentration and acute myocardial infarction (AMI) in patients with ST-elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI). In this study, patients who presented with chest pain (STEMI, NSTEMI, or non-cardiac chest pain) were included, i.e. 49 patients with non-cardiac chest pain (control) and 66 patients hospitalised with AMI. In the AMI group, 35 patients had NSTEMI and 31 had STEMI. Serum subfatin concentrations were determined via enzyme-linked immunosorbent assay (ELISA). Descriptive data on the patients and their comorbidities were recorded, and subfatin concentrations were analysed. Subfatin concentrations were significantly different in the control, STEMI and NSTEMI groups (P = 0.002). In addition, subfatin concentrations were significantly lower in patients in the NSTEMI group than those in the control group (P < 0.001), but there was no significant difference between STEMI and the control group (P = 0.143). The receiver operating characteristic (ROC) analysis performed for differentiating the AMI and control groups found that subfatin had 64% sensitivity and 69% specificity, whereas troponin had 59% sensitivity and 95% specificity. In patients with AMI, the ROC analysis for differentiating NSTEMI from STEMI found that subfatin had 94% sensitivity and 41% specificity, while troponin had 65% sensitivity and 88% specificity. Subfatin concentrations were lower in patients without STEMI than in patients with STEMI. Subfatin concentration is associated with NSTEMI

Intraocular Hemorrhage due to use of Sildenafil in a Patient with Diabetes

Sildenafil is one of the most commonly used drugs for sexual dysfunction or to increase libido, and it regulates endothelial nitric oxide synthase enzyme via selective phosphodiesterase-V inhibition. Sildenafil can be easily obtained without a medical indication or prescription yet it is not considered as a completely safe medication. Hemoptysis and hemorrhagic stroke are some important adverse effects of sildenafil. The case of the current report was a 67-year-old diabetic patient with simultaneous anterior and posterior segment hemorrhage after the use of 100 mg sildenafil citrate. Anterior chamber clearance and pars plana vitrectomy were performed for the patient because the hyphema and vitreous hemorrhage did not resolve during the follow-up period. There are very limited data available in the literature suggesting an increase in the risk of hyphema or vitreous hemorrhage due to the use of sildenafil. This is the first report that reveals the bleeding effect of sildenafil use in a patient with type 2 diabetes

The Relationship of Neutrophil to Lymphocyte Ratio with Vitreomacular Traction Syndrome

This study was conducted to reveal the role of systemic low-grade inflammation by calculating the Neutrophil/Lymphocyte Ratio (NLR) in Vitreomacular Traction Syndrome (VMTS) of different etiologies. A retrospective examination was made of the medical records at a tertiary referral hospital. The study included 31 patients with diabetic VMTS, 27 patients with idiopathic VMTS, and 35 healthy subjects as the control group. The White Blood Cell (WBC) counts and Neutrophil-to-Lymphocyte Ratio (NLR) was compared. There were  insignificant differences between the groups in terms of mean age and female/male ratio (P&gt;0.05). The mean ± Standard Deviation (SD) of NLR was calculated as 2.43 ± 0.83 in the diabetic VMTS group, 2.38 ± 0.96 in the idiopathic VMTS group, and 1.83 ± 0.52 in the control group (P=0.007). The values of the diabetic and idiopathic VMTS groups were significantly higher than those of the control group (P=0.002 and P=0.032, respectively). However, differences between the diabetic and idiopathic VMTS groups were insignificant (P=0.651). This study found significantly higher NLR in patients with diabetic and idiopathic VMTS than the control group. Elevated NLR could therefore be a potential indicator of VMTS, irrespective of the etiology

The Correlation between Changes in Biochemical Parameters and Central Macular Thickness in Patients with Non-Proliferative Diabetic Retinopathy

This study aimed at evaluating the correlation between changes in Hemoglobin A1c (HbA1c) and fasting serum lipids, and Central Macular Thickness (CMT) in patients with Non-Proliferative Diabetic Retinopathy (NPDR). In the current research, both eyes of 68 patients with mild or moderate NPDR, without clinically significant macular edema, were studied. Levels of fasting serum lipids, HbAlc, and CMT were measured during the first visit and at the end of the follow-up period (3 months). For statistical analysis, CMTs of each eye were studied and the correlation of changes was investigated. Additionally, the direction of changes in CMT for each eye was determined, and whether the changes in both eyes were symmetrical was investigated. Out of 68 patients, 24 were male and 44 were female. The mean CMT of all eyes was 290.05 ± 48.90 µm during the first visit and 286.80 ± 37.57 µm on the 3rd month follow-up. The mean HbAlc was 8.71 ± 1.82% at first visit to the hospital and the mean HbAlc was 8.39 ± 1.65% at the final visit. Although the changes in HbA1c and CMT during the follow-up period were statistically insignificant, the correlation of these 2 values was statistically significant (p=0.01). However, amongst l3 patients, the CMTs were asymmetrically changed in each eye during the follow-up period. To the best of the author’s knowledge, this was the first study, which indicated a significant correlation in changes of CMT and HbA1c, even amongst patients with low-grade diabetic retinopathy. Demonstration of asymmetric changes in CMT of each treatment-naive eye of the same patient, during changes in systemic conditions, was another important finding of this study

Effects of chromic acid anodizing on fatigue behavior of 7050 T7451 aluminum alloy

The effect of chromic acid anodizing (CAA) surface treatment on 7050 T7451 aluminum alloy was presented in this study in terms of fatigue behavior. CAA is a treatment against corrosion by producing aluminum oxide layer (Al2O3) at the surface. However, fatigue performance of 7050 T7451 is affected by the coating. In this study, eight different CAA processes were examined with regard to etching stage of pre-treatments by using an alkaline etchant and/or acid etchants with various immersion times. Optical microscopic examinations were applied in order to determine pitting characteristics for the selection of CAA process parameters before fatigue tests. A CAA process was selected among eight processes in terms of pitting characteristics in order to apply fatigue specimens. Four fatigue test groups were determined to investigate bare condition of 7050 T7451 and sub-stages of the CAA particularly. Constant amplitude axial fatigue tests were conducted on specimens at 91 Hz at stress ratio (R) -1 until run-out criteria, which was 106 cycles. Fatigue life reduction was determined due to pretreatments of CAA. Fracture surfaces of the specimens were examined by scanning electron microscope (SEM) to investigate morphology and crack initiation sites

Comparison of 9.0 and 9.2 mm Flap Diameter Options of Femtosecond Laser In-Situ Keratomileusis for Hypermetropia and Hypermetropic Astigmatism

Aim. To compare the postoperative one-year outcomes of asphericity (Q) and high order aberration (HOA) values of 9.0 and 9.2 mm diameter flap groups in hypermetropia and hypermetropic astigmatism subjects who underwent femtosecond laser in-situ keratomileusis (LASIK). Materials and Methods. The study included 68 eyes of 34 patients. A femtosecond laser platform (Allegrato Wave, Wavelight AG, Erlangen, Germany) was used for flap cutting. Corneal stroma was ablated using Wavelight EX500 with wavefront-optimized profile (WaveLight GmbH, Erlangen, Germany). 9.0 mm flap diameter was randomly chosen for one eye, and 9.2 mm flap diameter was chosen for the fellow eye. Two eyes of the patients who used two different flap diameters were enrolled into two different groups. Corneal stroma was ablated using Wavelight EX500 with wavefront-optimized profile (WaveLight GmbH, Erlangen, Germany). Postoperative one-year outcomes of Q and HOA values of 9.0 and 9.2 mm diameter flap groups were compared statistically. Results. The preoperative manifest refraction spherical equivalents of the 9.0 and 9.2 mm diameter flap groups were 1.86 +/- 1.81 D and 1.69 +/- 1.99 D (p=0.754). No intraoperative or postoperative complications were observed. At postoperative one-year, Q values were 0.98 +/- 0.13 D and 0.91 +/- 0.15 D (p=0.029). HOAs including horizontal and vertical coma, horizontal and vertical trefoil, spherical aberration, and second order vertical coma were not significantly different (p>0.05 for all). Total HOA values were 1.62 +/- 0.14 and 1.40 +/- 0.16, in the 9.0 and 9.2 mm diameter flap groups, respectively (p<0.001). Conclusion. Both the 9.0 and 9.2 mm diameter flap options in femtosecond LASIK are equally safe and effective. Many of the HOA values are similar in both options, and better results were provided in terms of total HOA and Q values with the 9.2 mm diameter flap option. This study was registered with trial registration number 118-011

Treatment of Retinal Pigment Epithelial Detachment

Anatomical separation of the retinal pigment epithelium from the Bruch membrane is defined as retinal pigment epithelial detachment (PED) andit is classified as drusenoid, serous, and vascularized. Vascularized PED is mostly associated with choroidal neovascularmembrane due to age-related macular degeneration and the risk of vision loss is high in this situation. Studies show that all of baseline values including BCVA, PED height, subretinal fluid, central macular thickness, PED volume, vertical dimension, presence of coincident macular pathology, reflectivity and morphology on optical coherence tomography have prognostic importance. Current treatment protocols mainly based on intravitreal injection of anti-vascular endothelial growth factor (VEGF).Even the bevacizumab was the first anti-VEGF that was used for treatment in PED, there are several reports show the insufficiency of bevacizumab. In treatment-na&iuml;ve eyes, both of ranibizumab and aflibercepthave similar effect in vascularized PED. In treatment-resistant eyes, high dose bevacizumab or switching therapy of anti-VEGF procedures can be effective when considering of all cases, aflibercept seems more effective than other options.We aimed in this manuscript, to give a general information about different characteristics of PEDs and to investigate the treatment strategies in the light of current literature

Parentage assignment inSalmo truttastrains and their crossbreeds with known mating

WOS: 000568459500001Brown trout,Salmo truttais a widespread fish species throughout the Europe yet most of the natural populations of the species is in decline due to the anthropogenic pressures. Hatchery based stock enhancement is commonly used to restore depleted populations. Tracking pedigree information is useful for evaluating performance of stocked offspring and for examining introgression where stocking practices are being implemented. in this study, parentage assignment powers of 16 previously developed microsatellite markers have been evaluated in four brown trout strains and their reciprocal crossbreeds. the number of alleles per locus ranged between 3 (Str73INRA) -24 (T3-13). Observed (H-O) and expected heterozygosity (H-E) was between 0.188 and 0.854 and 0.175-0.903, respectively. According to the simulation analysis with prior known parental and filial information, of the 204 offspring tested, correct assignment rate of the eight most informative microsatellite marker to their parental pairs was 96.08% and that of 15 loci was 98.04%. Having more than eight markers boosted only 1.96% extra power of assignment. Meanwhile correct assignment rate of five loci was resulted only 85.29%. Our results demonstrate that microsatellite markers are reliable and effective tools for the parentage assignment in brown trout strains and their reciprocal crossbreeds. the findings obtained in the present study would also be useful for performance evaluation of stocked fish, detecting crossbreeds and examining introgression into natural populations.Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK: 214O595]This project was funded by Scientific and Technological Research Council of Turkey (TUBITAK: 214O595)