Creating Physical 3D Stereolithograph Models of Brain and Skull

The human brain and skull are three dimensional (3D) anatomical structures with complex surfaces. However, medical images are often two dimensional (2D) and provide incomplete visualization of structural morphology. To overcome this loss in dimension, we developed and validated a freely available, semi-automated pathway to build 3D virtual reality (VR) and hand-held, stereolithograph models. To evaluate whether surface visualization in 3D was more informative than in 2D, undergraduate students (n = 50) used the Gillespie scale to rate 3D VR and physical models of both a living patient-volunteer's brain and the skull of Phineas Gage, a historically famous railroad worker whose misfortune with a projectile tamping iron provided the first evidence of a structure-function relationship in brain. Using our processing pathway, we successfully fabricated human brain and skull replicas and validated that the stereolithograph model preserved the scale of the VR model. Based on the Gillespie ratings, students indicated that the biological utility and quality of visual information at the surface of VR and stereolithograph models were greater than the 2D images from which they were derived. The method we developed is useful to create VR and stereolithograph 3D models from medical images and can be used to model hard or soft tissue in living or preserved specimens. Compared to 2D images, VR and stereolithograph models provide an extra dimension that enhances both the quality of visual information and utility of surface visualization in neuroscience and medicine

Multiple choice questions are superior to extended matching questions to identify medicine and biomedical sciences students who perform poorly.

Contains fulltext : 125684.pdf (publisher's version ) (Open Access)In recent years, medical faculties at Dutch universities have implemented a legally binding study advice to students of medicine and biomedical sciences during their propaedeutic phase. Appropriate examination is essential to discriminate between poor (grade /=8) students. Therefore, we compared the discriminatory properties of extended matching questions (EMQs) versus multiple-choice questions (MCQs) and identified the role of sex, age and examination preference on this score. Data were collected for 452 first-year medical and biomedical science students during three distinct course examinations: one examination with EMQ only, one with MCQ only and one mixed examination (including EMQ and MCQ). Logistic regression analysis revealed that MCQ examination was 3 times better in identifying poor students compared with EMQ (RR 3.0, CI 2.0-4.5), whereas EMQ better detected excellent students (average grade >/=8) (RR 1.93, CI 1.47-2.53). Mixed examination had comparable characteristics to MCQ. Sex and examination preference did not impact the score of the student. Students >/=20 years had a 4-fold higher risk ratio of obtaining a poor grade (<6) compared with students </=18 years old (RR 4.1, CI 2.1-8.0). Given the strong discriminative capacity of MCQ examinations to identify poor students, we recommend the use of this type of examination during the propaedeutic phase of medicine and biomedical science study programmes, in the light of the binding study advice.1 november 201

Wax Anatomical Models and Neuroscience: From Artistic Italian Creation to Therapeutic Approach

Wax modelling has been used since ancient times with its first application in art in the fifteenth century involving famous artists with knowledge of anatomy. It was only in the seventeenth century that coloured ceroplastic began to be used for teaching anatomy as valid alternative to dissected human bodies, including also neuropathological. The origin of this scientific approach was born in central Italy, in Florence and Bologna in the eighteenth century, and immediately spread to other Italian cities, and Europe, and throughout the rest of the world. Wax neuro-models were shown as artefacts and destined to train young doctors in anatomical knowledge. Nowadays, wax is often considered an old-fashioned art form but what is not well known is that wax has a useful therapeutic application in medicine, with a particular emphasis in neurosurgery