On the role of magnetic reconnection in jet/accretion disk systems

The most accepted model for jet production is based on the magneto-centrifugal acceleration out off an accretion disk that surrounds the central source (Blandford & Payne, 1982). This scenario, however, does not explain, e.g., the quasi-periodic ejection phenomena often observed in different astrophysical jet classes. de Gouveia Dal Pino & Lazarian (2005) (hereafter GDPL) have proposed that the large scale superluminal ejections observed in microquasars during radio flare events could be produced by violent magnetic reconnection (MR) episodes. Here, we extend this model to other accretion disk systems, namely: active galactic nuclei (AGNs) and young stellar objects (YSOs), and also discuss its role on jet heating and particle acceleration.Comment: To be published in the IAU Highlights of Astronomy, Volume 15, XXVII IAU General Assembly, August 2009, Ian F. Corbett et al., eds., 201

Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia

This is the final version. Available on open access from Elsevier via the DOI in this recordThe delivery of peptide drugs to the brain is challenging, principally due to the blood brain barrier and the low metabolic stability of peptides. Exclusive delivery to the brain with no peripheral exposure has hitherto not been demonstrated with brain quantification data. Here we show that polymer nanoparticles encapsulating leucine5-enkephalin hydrochloride (LENK) are able to transport LENK exclusively to the brain via the intranasal route, with no peripheral exposure and nanoparticle localisation is observed within the brain parenchyma. Animals dosed with LENK nanoparticles (NM0127) showed a strong anti-nociceptive response in multiple assays of evoked and on going pain whereas animals dosed intranasally with LENK alone were unresponsive. Animals did not develop tolerance to the anti-hyperalgesic activity of NM0127 and NM0127 was active in morphine tolerant animals. A microparticulate formulation of clustered nanoparticles was prepared to satisfy regulatory requirements for nasal dosage forms and the polymer nanoparticles alone were found to be biocompatible, via the nasal route, on chronic dosing.The UK Engineering and Physical Sciences Research Council(EP/K502340/1), Nanomerics Ltd.(NM12TSB-NPP) and Innovate UK(16939-124181) are acknowledged for funding

Wireless Underground Channel Modeling

A comprehensive treatment of wireless underground channel modeling is presented in this chapter. The impacts of the soil on bandwidth and path loss are analyzed. A mechanism for the UG channel sounding and multipath characteristics analysis is discussed. Moreover, novel time-domain impulse response model for WUC is reviewed with the explanation of model parameters and statistics. Furthermore, different types of the through-the-soil wireless communications are surveyed. Finally, the chapter concludes with discussion of the UG wireless statistical model and path loss model for through-the-soil wireless communications in decision agriculture. The model presented in this chapter is also validated with empirical data

Positron annihilation signatures associated with the outburst of the microquasar V404 Cygni

This document is the Accepted Manuscript version of the following article: Thomas Siegert, et al, ‘Positron annihilation signatures associated with the outburst of the microquasar V404 Cygni’, Nature: International Journal of Science, Vol. 531: 341-343, March 2016, DOI: https://doi.org/10.1038/nature16978. Content in the UH Research Archive is made available for personal research, educational, and non-commercial purposes only. Unless otherwise stated, all content is protected by copyright, and in the absence of an open license, permissions for further re-use should be sought from the publisher, the author, or other copyright holder.Microquasars1, 2, 3, 4 are stellar-mass black holes accreting matter from a companion star5 and ejecting plasma jets at almost the speed of light. They are analogues of quasars that contain supermassive black holes of 106 to 1010 solar masses. Accretion in microquasars varies on much shorter timescales than in quasars and occasionally produces exceptionally bright X-ray flares6. How the flares are produced is unclear, as is the mechanism for launching the relativistic jets and their composition. An emission line near 511 kiloelectronvolts has long been sought in the emission spectrum of microquasars as evidence for the expected electron–positron plasma. Transient high-energy spectral features have been reported in two objects7, 8, but their positron interpretation9 remains contentious. Here we report observations of γ-ray emission from the microquasar V404 Cygni during a recent period of strong flaring activity10. The emission spectrum around 511 kiloelectronvolts shows clear signatures of variable positron annihilation, which implies a high rate of positron production. This supports the earlier conjecture that microquasars may be the main sources of the electron–positron plasma responsible for the bright diffuse emission of annihilation γ-rays in the bulge region of our Galaxy11. Additionally, microquasars could be the origin of the observed megaelectronvolt continuum excess in the inner Galaxy.Peer reviewe

Generation of Functional CLL-Specific Cord Blood CTL Using CD40-Ligated CLL APC

PMCID: PMC3526610This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Underground Phased Arrays and Beamforming Applications

This chapter presents a framework for adaptive beamforming in underground communication. The wireless propagation is thoroughly analyzed to develop a model using the soil moisture as an input parameter to provide feedback mechanism while enhancing the system performance. The working of array element in the soil is analyzed. Moreover, the effect of soil texture and soil moisture on the resonant frequency and return loss is studied in detail. The wave refraction from the soil–air interface highly degrades the performance of the system. Furthermore, to beam steering is done to achieve high gain for lateral component improving the UG communication. The angle enhancing the lateral wave depends upon dielectric properties and usually ranges from 0∘ to 16∘. These dielectric properties change with the change in soil moisture and soil texture. It is shown from the experiments that optimal UG lateral angle is high at lower soil moisture readings and decreases with decrease in soil moisture. A planar structure of antenna array and different techniques for optimization are proposed for enhanced soil moisture adaptive beamforming. UG channel impulse response is studied from the beamforming aspect to identify the components of EM waves propagating through the soil. An optimum steering method for beamforming is presented which adapts to the changing values of soil moisture. Finally, the limitations of UG beamforming are presented along with the motivation to use it

Accreting Black Holes

This chapter provides a general overview of the theory and observations of black holes in the Universe and on their interpretation. We briefly review the black hole classes, accretion disk models, spectral state classification, the AGN classification, and the leading techniques for measuring black hole spins. We also introduce quasi-periodic oscillations, the shadow of black holes, and the observations and the theoretical models of jets.Comment: 41 pages, 18 figures. To appear in "Tutorial Guide to X-ray and Gamma-ray Astronomy: Data Reduction and Analysis" (Ed. C. Bambi, Springer Singapore, 2020). v3: fixed some typos and updated some parts. arXiv admin note: substantial text overlap with arXiv:1711.1025

Signals in the Soil: Underground Antennas

Antenna is a major design component of Internet of Underground Things (IOUT) communication system. The use of antenna, in IOUT, differs from traditional communication in that it is buried in the soil. Therefore, one of the main challenges, in IOUT applications, is to establish a reliable communication. To that end, there is a need of designing an underground-specific antenna. Three major factors that can impact the performance of a buried antenna are: (1) effect of high soil permittivity changes the wavelength of EM waves, (2) variations in soil moisture with time affecting the permittivity of the soil, and (3) difference in how EM waves propagate during aboveground (AG) and underground (UG) communications. For the third challenge above, it is to be noted that lateral waves are dominant component in EM during UG2UG communication and suffer lowest attenuation as compared to other, direct and reflected, components. Therefore, antennas used for over-the-air (OTA) communication will not be suitable for UG communication because of impedance mismatch. This chapter focuses on developing a theoretical model for understanding the impact of soil on antenna by conducting experiments in different soil types (silty clay loam, sandy, and silt loam soil) and indoor testbed. The purpose of the model is to predict UG antenna resonance for designing efficient communication system for IOUT. Based on the model a wideband planar antenna is designed considering soil dispersion and soil–air interface reflection effect which improves the communication range five times from the antennas designed only for the wavelength change in soil. Furthermore, it also focuses on developing an impedance model to study the effect of changing wavelength in underground communication. It is also discussed how soil–air interface and soil properties effect the return loss of dipole antenna

Electromagnetic Characteristics of the Soil

The electromagnetic characteristics of the soil are discussed in this chapter. The characteristics of porous bedrock, soil medium, and impacts of rain attenuations are also presented. The models of dielectric soil properties are studied with a rigorous focus on the constitutive parameters of subsurface soil medium. Moreover, the permittivity and wavenumber in soil are explained. In addition, the frequency-dependent dielectric properties such as dispersion in soil, absorption characteristic, and penetration depth versus frequency are reviewed. Furthermore, the effective permittivity of soil–water mixture for through-the soil-propagation mechanism is analyzed thoroughly