11,104 research outputs found

    Tinea pedis: diagnosis and management

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    Tinea pedis is one of the most commonly encountered foot infections. The fact that in most cases it is easily treatable yet still prevalent in the general population suggests it is often undiagnosed or remains untreated by health care professionals and patients. The most common agent is Trichophyton rubrum which is often mistaken for dry skin in its presentation. Treatment should include curative as well as preventative measures where possible

    A research framework for traditional fisheries

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    Small scale fisheries, Fisheries, Research

    Sub-Critical Closed String Field Theory in D Less Than 26

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    We construct the second quantized action for sub-critical closed string field theory with zero cosmological constant in dimensions 2≤D<26 2 \leq D < 26, generalizing the non-polynomial closed string field theory action proposed by the author and the Kyoto and MIT groups for D=26D = 26. The proof of gauge invariance is considerably complicated by the presence of the Liouville field ϕ\phi and the non-polynomial nature of the action. However, we explicitly show that the polyhedral vertex functions obey BRST invariance to all orders. By point splitting methods, we calculate the anomaly contribution due to the Liouville field, and show in detail that it cancels only if D−26+1+3Q2=0D - 26 + 1 + 3 Q ^ 2 = 0 , in both the bosonized and unbosonized polyhedral vertex functions. We also show explicitly that the four point function generated by this action reproduces the shifted Shapiro-Virasoro amplitude found from c=1c=1 matrix models and Liouville theory in two dimensions. LATEX file.Comment: 28 pages, CCNY-HEP-93-

    Correction for founder effects in host-viral association studies via principal components

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    Viruses such as HIV and Hepatitis C (HCV) replicate rapidly and with high transcription error rates, which may facilitate their escape from immune detection through the encoding of mutations at key positions within human leukocyte antigen (HLA)-specific peptides, thus impeding T-cell recognition. Large-scale population-based host-viral association studies are conducted as hypothesis-generating analyses which aim to determine the positions within the viral sequence at which host HLA immune pressure may have led to these viral escape mutations. When transmission of the virus to the host is HLA-associated, however, standard tests of association can be confounded by the viral relatedness of contemporarily circulating viral sequences, as viral sequences descended from a common ancestor may share inherited patterns of polymorphisms, termed 'founder effects'. Recognizing the correspondence between this problem and the confounding of case-control genome-wide association studies by population stratification, we adapt methods taken from that field to the analysis of host-viral associations. In particular, we consider methods based on principal components analysis within a logistic regression framework motivated by alternative formulations in the Frisch-Waugh-Lovell Theorem. We demonstrate via simulation their utility in detecting true host-viral associations whilst minimizing confounding by associations generated by founder effects. The proposed methods incorporate relatively robust, standard statistical procedures which can be easily implemented using widely available software, and provide alternatives to the more complex computer intensive methods often implemented in this area

    Normal modes of carbon nanotubes: similarities and differences with their continuum counterpart

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    Carbon nanotubes (CNTs) possess a range of unusually interesting and useful physicochemical properties. In this paper, the mechanical properties of single wall CNTs are investigated via free vibration normal modes using molecular mechanics models. The forcefield used is empirical and the usual assumptions of potential energy contributions coming from bondstretching, bond angle bending, and bond twisting for two, three, and four atom interactions respectively, are made. The validity of continuum behaviour is examined by comparing the modal spacing obtained from the molecular mechanics models and that obtained from classical continuum elastodynamics. The breakdown of continuum behaviour is systematically characterised for various combinations of length to diameter ratio as well as for the number of atoms per circumference

    Balanced dynamics in the Tropics

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    For the shallow-water equations on an equatorial beta plane, the properties of low-frequency Rossby waves and (mixed) Rossby-gravity waves are investigated. It is shown that in the low-frequency limit the horizontal divergence of these solutions is zero and their geopotential satisfies = f, where f = y is the Coriolis parameter and is the stream function of the non-divergent velocity field. This type of balance is rather different from the geostrophic balance satisfied by Kelvin waves. It can be used to formulate a balanced potential vorticity equation in the single variable that, while filtering out Kelvin waves and inertia-gravity waves, exactly reproduces Rossby waves and Rossby-gravity waves in the low-frequency limit

    Don't gamble with Melanoma

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    A poster highlighting an acronym for the early recognition of melanoma on the foo
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