65 research outputs found

    How Well Do We (and Will We) Know Solar Neutrino Fluxes and Oscillation Parameters?

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    Assuming neutrino oscillations occur, the pp electron neutrino flux is uncertain by at least a factor of two, the 8B{\rm ^8B} flux by a factor of five, and the 7Be{\rm ^7Be} flux by a factor of forty-five. Calculations of the expected results of future solar neutrino experiments (SuperKamiokande, SNO, BOREXINO, ICARUS, HELLAZ, and HERON) are used to illustrate the extent to which these experiments will restrict the range of the allowed neutrino mixing parameters. We present an improved formulation of the ``luminosity constraint'' and show that at 95\% confidence limit this constraint establishes the best available limits on the rate of creation of pp neutrinos in the solar interior and provides the best upper limit to the 7Be{\rm ^7Be} neutrino flux.Comment: 37 pages, uuencoded Z-compressed postscript file (with figures); Submitted to Physical Review

    Solar Neutrinos and the Principle of Equivalence

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    We study the proposed solution of the solar neutrino problem which requires a flavor nondiagonal coupling of neutrinos to gravity. We adopt a phenomenological point of view and investigate the consequences of the hypothesis that the neutrino weak interaction eigenstates are linear combinations of the gravitational eigenstates which have slightly different couplings to gravity, f1Gf_1G and f2Gf_2G, f1f2<<1|f_1-f_2| << 1, corresponding to a difference in red-shift between electron and muon neutrinos, Δz/(1+z)f1f2\Delta z/(1+z) \sim |f_1 - f_2|. We perform a χ2\chi^2 analysis of the latest available solar neutrino data and obtain the allowed regions in the space of the relevant parameters. The existing data rule out most of the parameter space which can be probed in solar neutrino experiments, allowing only f1f23×1014|f_1 - f_2| \sim 3 \times 10^{-14} for small values of the mixing angle (2×103sin2(2θG)1022 \times 10^{-3} \le \sin^2(2\theta_G) \le 10^{-2}) and 1016<f1f2<101510^{-16} \stackrel{<}{\sim} |f_1 - f_2| \stackrel{<}{\sim}10^{-15} for large mixing (0.6sin2(2θG)0.90.6 \le \sin^2(2\theta_G) \le 0.9). Measurements of the 8B^8{\rm B}-neutrino energy spectrum in the SNO and Super-Kamiokande experiments will provide stronger constraints independent of all considerations related to solar models. We show that these measurements will be able to exclude part of the allowed region as well as to distinguish between conventional oscillations and oscillations due to the violation of the equivalence principle.Comment: 20 pages + 4 figures, IASSNS-AST 94/5

    Constraints on neutrino oscillation parameters from the measurement of day-night solar neutrino fluxes at Super-Kamiokande

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    A search for day-night variations in the solar neutrino flux resulting from neutrino oscillations has been carried out using the 504 day sample of solar neutrino data obtained at Super-Kamiokande. The absence of a significant day-night variation has set an absolute flux independent exclusion region in the two neutrino oscillation parameter space.Comment: 11 pages, 3 figures, submitted to PRL, single-spacin

    Neutrino masses: From fantasy to facts

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    Theory suggests the existence of neutrino masses, but little more. Facts are coming close to reveal our fantasy: solar and atmospheric neutrino data strongly indicate the need for neutrino conversions, while LSND provides an intriguing hint. The simplest ways to reconcile these data in terms of neutrino oscillations invoke a light sterile neutrino in addition to the three active ones. Out of the four neutrinos, two are maximally-mixed and lie at the LSND scale, while the others are at the solar mass scale. These schemes can be distinguished at neutral-current-sensitive solar & atmospheric neutrino experiments. I discuss the simplest theoretical scenarios, where the lightness of the sterile neutrino, the nearly maximal atmospheric neutrino mixing, and the generation of Δm2\Delta {m^2}_\odot & Δm2atm\Delta {m^2}_{atm} all follow naturally from the assumed lepton-number symmetry and its breaking. Although the most likely interpretation of the present data is in terms of neutrino-mass-induced oscillations, one still has room for alternative explanations, such as flavour changing neutrino interactions, with no need for neutrino mass or mixing. Such flavour violating transitions arise in theories with strictly massless neutrinos, and may lead to other sizeable flavour non-conservation effects, such as μe+γ\mu \to e + \gamma, μe\mu-e conversion in nuclei, unaccompanied by neutrino-less double beta decay.Comment: 33 pages, latex, 16 figures. Invited Talk at Ioannina Conference, Symmetries in Intermediate High Energy Physics and its Applications, Oct. 1998, to be published by Springer Tracts in Modern Physics. Festschrift in Honour of John Vergados' 60th Birthda

    Consensus guidelines on analgesia and sedation in dying intensive care unit patients

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    BACKGROUND: Intensivists must provide enough analgesia and sedation to ensure dying patients receive good palliative care. However, if it is perceived that too much is given, they risk prosecution for committing euthanasia. The goal of this study is to develop consensus guidelines on analgesia and sedation in dying intensive care unit patients that help distinguish palliative care from euthanasia. METHODS: Using the Delphi technique, panelists rated levels of agreement with statements describing how analgesics and sedatives should be given to dying ICU patients and how palliative care should be distinguished from euthanasia. Participants were drawn from 3 panels: 1) Canadian Academic Adult Intensive Care Fellowship program directors and Intensive Care division chiefs (N = 9); 2) Deputy chief provincial coroners (N = 5); 3) Validation panel of Intensivists attending the Canadian Critical Care Trials Group meeting (N = 12). RESULTS: After three Delphi rounds, consensus was achieved on 16 statements encompassing the role of palliative care in the intensive care unit, the management of pain and suffering, current areas of controversy, and ways of improving palliative care in the ICU. CONCLUSION: Consensus guidelines were developed to guide the administration of analgesics and sedatives to dying ICU patients and to help distinguish palliative care from euthanasia

    Standardising Clinical Caremaps: Model, Method and Graphical Notation for Caremap Specification

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    Standardising care can improve patient safety and outcomes, and reduce the cost of providing healthcare services. Caremaps were developed to standardise care, but contemporary caremaps are not standardised. Confusion persists in terms of terminology, structure, content and development process. Unlike existing methods in the literature, the approach, model and notation presented in this chapter pays special attention to incorporation of clinical decision points as first-class citizens within the modelling process. The resulting caremap with decision points is evaluated through creation of a caremap for women with gestational diabetes mellitus. The proposed method was found to be an effective way for comprehensively specifying all features of caremaps in a standardised way that can be easily understood by clinicians. This chapter contributes a new standardised method, model and notation for caremap content, structure and development

    Monoclonal Antibody and Fusion Protein Biosimilars Across Therapeutic Areas: A Systematic Review of Published Evidence

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