10,737 research outputs found
Case study the poultry industry in Colombia
"As developing countries open their economies further to trade, their food industries are striving to raise safety and quality standards in order to compete in new markets. Such is the case with the Colombian poultry industry... Critical questions face the Colombian poultry industry: Is it ready to compete with foreign poultry producers on price, quality, and safety? Can industry efforts to produce better quality products assure an increased share of domestic and regional markets? This brief reviews the private initiatives undertaken by the Colombian poultry industry to assure food safety in light of these questions." from TextFood safety ,food security ,Public health ,
Modeling the Dynamics of Online Learning Activity
People are increasingly relying on the Web and social media to find solutions to their problems in a wide range of domains. In this online setting, closely related problems often lead to the same characteristic learning pattern, in which people sharing these problems visit related pieces of information, perform almost identical queries or, more generally, take a series of similar actions. In this paper, we introduce a novel modeling framework for clustering continuous-time grouped streaming data, the hierarchical Dirichlet Hawkes process (HDHP), which allows us to automatically uncover a wide variety of learning patterns from detailed traces of learning activity. Our model allows for efficient inference, scaling to millions of actions taken by thousands of users. Experiments on real data gathered from Stack Overflow reveal that our framework can recover meaningful learning patterns in terms of both content and temporal dynamics, as well as accurately track users' interests and goals over time
Modeling the Dynamics of Online Learning Activity
People are increasingly relying on the Web and social media to find solutions to their problems in a wide range of domains. In this online setting, closely related problems often lead to the same characteristic learning pattern, in which people sharing these problems visit related pieces of information, perform almost identical queries or, more generally, take a series of similar actions. In this paper, we introduce a novel modeling framework for clustering continuous-time grouped streaming data, the hierarchical Dirichlet Hawkes process (HDHP), which allows us to automatically uncover a wide variety of learning patterns from detailed traces of learning activity. Our model allows for efficient inference, scaling to millions of actions taken by thousands of users. Experiments on real data gathered from Stack Overflow reveal that our framework can recover meaningful learning patterns in terms of both content and temporal dynamics, as well as accurately track users' interests and goals over time
Defects, Rigid Holography and -theorems
We consider a general scalar QFT with a linear defect in and a
surface defect in . Using holography and the Hamilton-Jacobi
formalism, we show that the functions controlling the defect RG flow
are the gradient of the entropy function. In the case of conformal field
theories, this allows the proof that the relevant -functions decrease
monotonically along the RG flow. We provide evidence that this property also
holds in the full quantum theory for general scalar field theories. An
obstruction to the gradient property seems to appear at two loop order when
fermions are added.Comment: 6 pages, no figures; v2: published versio
RG Flows and Stability in Defect Field Theories
We investigate defects in scalar field theories in four and six dimensions in
a double-scaling (semiclassical) limit, where bulk loops are suppressed and
quantum effects come from the defect coupling. We compute -functions up
to four loops and find that fixed points satisfy dimensional disentanglement --
i.e. their dependence on the space dimension is factorized from the coupling
dependence -- and discuss some physical implications. We also give an
alternative derivation of the functions by computing systematic
logarithmic corrections to the Coulomb potential. In this natural scheme,
functions turn out to be a gradient of a `Hamiltonian' function . We also obtain closed formulas for the dimension of scalar operators and
show that instabilities do not occur for potentials bounded from below. The
same formulas are reproduced using Rigid Holography.Comment: 35 pages, 1 figure; v2: added reference
From Parity to Preference-based Notions of Fairness in Classification
The adoption of automated, data-driven decision making in an ever expanding range of applications has raised concerns about its potential unfairness towards certain social groups. In this context, a number of recent studies have focused on defining, detecting, and removing unfairness from data-driven decision systems. However, the existing notions of fairness, based on parity (equality) in treatment or outcomes for different social groups, tend to be quite stringent, limiting the overall decision making accuracy. In this paper, we draw inspiration from the fair-division and envy-freeness literature in economics and game theory and propose preference-based notions of fairness -- given the choice between various sets of decision treatments or outcomes, any group of users would collectively prefer its treatment or outcomes, regardless of the (dis)parity as compared to the other groups. Then, we introduce tractable proxies to design margin-based classifiers that satisfy these preference-based notions of fairness. Finally, we experiment with a variety of synthetic and real-world datasets and show that preference-based fairness allows for greater decision accuracy than parity-based fairness
Yearly evolution of organ damage markers in diabetes or metabolic syndrome: data from the LOD-DIABETES study
<p>Abstract</p> <p>Background</p> <p>Cardiovascular disease morbidity-mortality is greater in people with type 2 diabetes mellitus or metabolic syndrome. The purpose of this study was to evaluate the yearly evolution of organ damage markers in diabetes or metabolic syndrome, and to analyze the associated factors.</p> <p>Methods</p> <p>An observational prospective study was carried out in the primary care setting, involving 112 patients: 68 diabetics and 44 subjects with metabolic syndrome, subjected to 12 months of follow-up. Measurements: traditional cardiovascular risk factors (blood pressure, blood glucose, lipids, smoking, body mass index (BMI) and) and non-traditional risk factors (waist circumference, hsC Reactive Protein and fibrinogen); subclinical vascular (carotid intima-media thickness, pulse wave velocity and ankle/brachial index), cardiac (Cornell voltage-duration product), renal organ damage (creatinine, glomerular filtration and albumin/creatinine index), and antihypertensive and lipid-lowering drugs.</p> <p>Results</p> <p>At baseline, the diabetics presented a mean age of 59.9 years, versus 55.2 years in the subjects with metabolic syndrome (p = 0.03). Diastolic blood pressure, total cholesterol and HDL-cholesterol were lower among the patients with diabetes, while blood glucose and HbA1c, as well as antihypertensive and lipid-lowering drug use, were greater. At evaluation after one year, the diabetics showed a decrease in BMI (-0.39), diastolic blood pressure (-3.59), and an increase in fibrinogen (30.23 mg/dL), ankle/brachial index (0.07) and the number of patients with ankle/brachial index pathologic decreased in 6. In turn, the patients with metabolic syndrome showed an increase in HDL-cholesterol (1-91 mg/dL), fibrinogen (25.54 mg/dL), Cornell voltage-duration product (184.22 mm/ms), ankle/brachial index (0.05) and the use of antihypertensive and lipid-lowering drugs, and a reduction in serum glucose (3.74 mg/dL), HOMA, systolic (-6.76 mmHg), diastolic blood pressure (-3.29 mmHg), and pulse wave velocity (-0.72 m/s). The variable that best predicted a decrease in pulse wave velocity in subjects with metabolic syndrome was seen to be an increase in antihypertensive drug use.</p> <p>Conclusions</p> <p>The annual assessment of cardiovascular risk factors and the decrease in pulse wave velocity was more favorable in the patients with metabolic syndrome, probably influenced by the increased percentage of subjects treated with antihypertensive and lipid lowering drugs in this group.</p
A role for SUMO modification in transcriptional repression and activation
Since the discovery of the SUMO (small ubiquitin-like modifier) family of proteins just over a decade ago, a plethora of substrates have been uncovered including many regulators of transcription. Conjugation of SUMO to target proteins has generally been considered as a repressive modification. However, there are now a growing number of examples where sumoylation has been shown to activate transcription. Here we discuss whether there is something intrinsically repressive about sumoylation, or if the outcome of this modification in the context of transcription will prove to be largely substrate-dependent. We highlight some of the technical challenges that will be faced by attempting to answer this question
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