278 research outputs found
Bounds on changes in Ritz values for a perturbed invariant subspace of a Hermitian matrix
The Rayleigh-Ritz method is widely used for eigenvalue approximation. Given a
matrix with columns that form an orthonormal basis for a subspace \X, and
a Hermitian matrix , the eigenvalues of are called Ritz values of
with respect to \X. If the subspace \X is -invariant then the Ritz
values are some of the eigenvalues of . If the -invariant subspace \X
is perturbed to give rise to another subspace \Y, then the vector of absolute
values of changes in Ritz values of represents the absolute eigenvalue
approximation error using \Y. We bound the error in terms of principal angles
between \X and \Y. We capitalize on ideas from a recent paper [DOI:
10.1137/060649070] by A. Knyazev and M. Argentati, where the vector of absolute
values of differences between Ritz values for subspaces \X and \Y was
weakly (sub-)majorized by a constant times the sine of the vector of principal
angles between \X and \Y, the constant being the spread of the spectrum of
. In that result no assumption was made on either subspace being
-invariant. It was conjectured there that if one of the trial subspaces is
-invariant then an analogous weak majorization bound should only involve
terms of the order of sine squared. Here we confirm this conjecture.
Specifically we prove that the absolute eigenvalue error is weakly majorized by
a constant times the sine squared of the vector of principal angles between the
subspaces \X and \Y, where the constant is proportional to the spread of
the spectrum of . For many practical cases we show that the proportionality
factor is simply one, and that this bound is sharp. For the general case we can
only prove the result with a slightly larger constant, which we believe is
artificial.Comment: 12 pages. Accepted to SIAM Journal on Matrix Analysis and
Applications (SIMAX
Basal pseudoaneurysm of the lateral wall of the left ventricle – case report
Left ventricle pseudoaneurysm is a rare but serious complication, most often secondary to myocardial infarction. It is associated with high mortality due to a significant risk of rupture. We present a case of a patient with a large basal pseudoaneurysm of the lateral wall of the left ventricle. The pseudoaneurysm is discovered from a chest radiography performed after a COVID-19 infection. The diagnosis is confirmed by echocardiography and ventriculography. The patient underwent surgical treatment by endoventricular patch plasty – Dor procedure. The patient in our case lacked the typical symptoms and ECG features, furthermore he had no history of myocardial infarction, cardiac surgery, trauma or endocarditis
Homage to George E. Palade Cell Protein Secretion in Vascular Biology: Overview and Updates
Abstract
This short overview and updates expresses our brain-and-heart homage to George Emil Palade, "the most influential cell biologist ever". In his 1971 paper Palade wrote for Albert Claude, the founder of biological electron microscopic method: "Seldom has a field owed so much to a single man". Herein, we articulate the same words for George Palade, the Teacher of many generations in cell biology research and education. Accordingly, we focus on two paradigm shifts in the cell biology, namely (i) the transition from light to transmission electron microscopy in studying cell protein secretion made by George Palade, and (ii) the transition from contractile to secretory phenotype of vascular smooth muscle cells made by Maria Daria Haust followed and developed by our research group. Altogether, we argue that one of the present challenges in vascular biology is to cultivate secreto-centric thinking and thus further focusing on how we could make the vascular muscle's secretory pathways work for the benefit of human's cardiovascular health
NGF-ome: its metabotrophic expression. Homage to Rita Levi-Montalcini
Nowadays, in the postgenome time, many "-ome" studies have emerged including proteome, transcriptome, interactome, metabolome, adipokinome, connectome. In this vein, the catchall term NGF-ome embodies all the actions of NGF in health and disease. Accordingly, the present Festschrift, also tabula gratulatoria, is to honor and acknowledge the contributions of the distinguished neuroscientist and magistra Rita Levi-Montalcini, the Nobel Prize winner-1986 for the discoverer of NGF. Today, NGF and another neurotrophin, brain-derived neuroptrophic factor (BDNF), are well recognized to mediate multiple biological phenomena, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. These latter effects are involved in the maintenance of cardiometabolic homeostasis (glucose and lipid metabolism as well as energy balance, and cardioprotection). Circulating and/or tissue levels of NGF and BDNF are altered in cardiometabolic diseases (atherosclerosis, obesity, type 2 diabetes, metabolic syndrome, and type 3 diabetes/Alzheimer's disease). A hypothesis thus emerged that a metabotrophic deficit due to the reduction of NGF/BDNF availability and/or utilization may be implicated in the pathogenesis of cariometabolic and neurodegenerative diseases. The present challenge is therefore to cultivate a metabotrophic thinking about how we can modulate NGF/BDNF secretion and signaling for the benefit of human cardiometabolic and mood health.Biomedical Reviews 2010; 21: 25-29
NA49 results on hadron production: indications of the onset of deconfinement ?
The NA49 experiment at the CERN SPS measured the energy and system size
dependence of particle production in A+A collisions. A change of the energy
dependence of several hadron production properties at low SPS energies is
observed which suggests a scenario requiring the onset of deconfinement.Comment: XXXV International Symposium on Multiparticle Dynamics 200
Energy dependence of particle ratio fluctuations in central Pb+Pb collisions from ~6.3 to 17.3 GeV
We present measurements of the energy dependence of event-by-event
fluctuations in the K/pi and (p + \bar{p})/pi multiplicity ratios in heavy ion
collisions at the CERN SPS. The particle ratio fluctuations were obtained for
central Pb+Pb collisions at five collision energies, \sqrt{s_{_{NN}}}, between
6.3 and 17.3 GeV. After accounting for the effects of finite-number statistics
and detector resolution, we extract the strength of non-statistical
fluctuations at each energy. For the K/pi ratio, larger fluctuations than
expected for independent particle production are found at all collision
energies. The fluctuations in the (p + \bar{p})/pi ratio are smaller than
expectations from independent particle production, indicating correlated pion
and proton production from resonance decays. For both ratios, the deviation
from purely statistical fluctuations shows an increase towards lower collision
energies. The results are compared to transport model calculations, which fail
to describe the energy dependence of the K/pi ratio fluctuations.Comment: 11 pages, 10 figures, update to published versio
Upper Limit of D0 Production in Central Pb-Pb Collisions at 158A GeV
Results are presented from a search for the decays D0 -> Kmin piplus and
D0bar -> Kplus pimin in a sample of 3.8x10^6 central Pb-Pb events collected
with a beam energy of 158A GeV by NA49 at the CERN SPS. No signal is observed.
An upper limit on D0 production is derived and compared to predictions from
several models.Comment: REVTEX 5 pages, 4 figure
Rapidity and energy dependence of the electric charge correlations in A+A collisions at the SPS energies
Results from electric charge correlations studied with the Balance Function
method in A+A collisions from 20\emph{A} to 158\emph{A} GeV are presented in
two different rapidity intervals: In the mid-rapidity region we observe a
decrease of the width of the Balance Function distribution with increasing
centrality of the collision, whereas this effect vanishes in the forward
rapidity region.
Results from the energy dependence study in central Pb+Pb collisions show
that the narrowing of the Balance Function expressed by the normalised width
parameter \textit{W} increases with energy towards the highest SPS and RHIC
energies.
Finally we compare our experimental data points with predictions of several
models. The hadronic string models UrQMD and HIJING do not reproduce the
observed narrowing of the Balance Function. However, AMPT which contains a
quark-parton transport phase before hadronization can reproduce the narrowing
of the BF's width with centrality. This confirms the proposed sensitivity of
the Balance Function analysis to the time of hadronization.Comment: Submitted in Phys. Rev.
Bose-Einstein correlations of pion pairs in central Pb+Pb collisions at CERN SPS energies
Measurements of Bose-Einstein correlations of pion pairs in central Pb+Pb
collisions were performed with the NA49 detector at the CERN SPS for beam
energies of 20A, 30A, 40A, 80A, and 158A GeV. Correlation functions were
measured in the longitudinally co-moving ``out-side-long'' reference frame as a
function of rapidity and transverse momentum in the forward hemisphere of the
reaction. Radius and correlation strength parameters were obtained from fits of
a Gaussian parametrization. The results show a decrease of the radius
parameters with increasing transverse momentum characteristic of strong radial
flow in the pion source. No striking dependence on pion-pair rapidity or beam
energy is observed. Static and dynamic properties of the pion source are
obtained from simultaneous fits with a blast-wave model to radius parameters
and midrapidity transverse momentum spectra. Predictions of hydrodynamic and
microscopic models of Pb+Pb collisions are discussed.Comment: 22 pages, 23 figure
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