321 research outputs found

    Association of the superior semicircular canal and tegmen tympani dehiscences and its relationship with the pneumatisation of the temporal bone

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    To analyse the degree of pneumatisation of the temporal bone when there is an association between dehiscence of the superior semicircular canal and dehiscence of the tegmen tympani. Materials and methods We analysed a retrospective CT study of 124 selected cases. A single inclusion criterion was applied: the presence of a dehiscence of the tegmen tympani. On the other hand, the degree of temporal pneumatisation was assessed by axial and coronal planes, and has been divided into the following grades O, I, II and III, according to the status and relationship of the mastoid, the bony labyrinth, the petrous segment of the carotid canal and sigmoid sinus. Results Of the 124 cases studied, 35 (28.2%) presented both dehiscences. In 26 of the 35 (47.3%), grade II pneumatisation, 4 (14,8%), grade I, and 5 (11,9%) grade III was observed, with a statistically significant relationship (p < 0.001). On the other hand, we did not find a significant relationship when relating both dehiscences in any age or sex group. However, when relating the degree of pneumatisation to sex, among those with grade III pneumatisation, the proportion of men (52.4%) was significantly higher than that of women (47.6%) (p = 0.017). Conclusion We have detected a statistically significant relationship between the coexistence of grade II pneumatisation and the presence of both dehiscences in the temporal bone

    Science, Technology, and Innovation Governance for Social Inclusion and Sustainable Development in Latin America

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    The introduction of the concept of governance in Latin America belongs to the neoliberal policies of privatization that tried to trace and assure that public funds, especially international loans, can overcome several corruption problems and the lag in the bargaining between public and private actors. The idea that transparency and accountability in the private actors that receive contracts from the States with the slogan of competitiveness reach bankruptcy. In this framework, studies in science, technology, and innovation (STI) began to interest in governance as a way to explain how policy and research networks create space, mechanisms, and instruments to negotiate and steer policies and actions and create a better future. The scientific challenges to solve complex problems need several actors and fields beyond traditional ministries and bureaucratic governments jurisdictions. Then, governance arises to understand the coordination between several stakeholders that are able to collaborate and develop systems to achieve common goals. This chapter introduces the book that covers the research shared in the congress “Governance of science, technology, and innovation for inclusive and sustainable development in Latin America” organized by the Network on Governance and Management of Science, Technology, and Innovation—(Red GCTI) with a critical point of view. The main contribution is to show the topics, approaches, controversies, trends, and challenges in the Latin American research of STI governance for social inclusion and sustainability

    Anatomical study about the variations in renal vasculature

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    Renal vascularization is classically described as a renal artery and vein. However, this vascular pattern presents numerous anatomical variations in terms of their number, origin and course due to ontogenetic alterations. The aim was to carry out a descriptive study of the renal vascular pattern observed during the dissection of cadavers intended for teaching purposes. A descriptive and observational study of renal vascular anatomy was carried out by dissecting 16 renal blocks from 8 cadavers donated to science and used for teaching at the Faculty of Medicine of the University of Zaragoza. The prevalence of arterial variations was 75% (56.3% for polar renal arteries, 12.5% for pre-hilar branching and 6.25% for double communicating arterial arch) and venous was 62.5% (12.5% for polar renal veins, 25% for late venous confluence, 6.25% for triple renal vein and 18.75% for double circumaortic renal vein). We conclude that the renal vascular anomalies occur with high frequency; for this reason, knowledge of these anomalies is extremely important for the correct planning of numerous medical-surgical activities

    Anatomical study about the variations in renal vasculature

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    Renal vascularization is classically described as a renal artery and vein. However, this vascular pattern presents numerous anatomical variations in terms of their number, origin and course due to ontogenetic alterations. The aim was to carry out a descriptive study of the renal vascular pattern observed during the dissection of cadavers intended for teaching purposes. A descriptive and observational study of renal vascular anatomy was carried out by dissecting 16 renal blocks from 8 cadavers donated to science and used for teaching at the Faculty of Medicine of the University of Zaragoza. The prevalence of arterial variations was 75% (56.3% for polar renal arteries, 12.5% for pre-hilar branching and 6.25% for double communicating arterial arch) and venous was 62.5% (12.5% for polar renal veins, 25% for late venous confluence, 6.25% for triple renal vein and 18.75% for double circumaortic renal vein). We conclude that the renal vascular anomalies occur with high frequency; for this reason, knowledge of these anomalies is extremely important for the correct planning of numerous medical-surgical activities

    UN MODELO MULTIDIMENSIONAL DE LA VIOLENCIA ESCOLAR EN MÉXICO: FACTORES FAMILIARES Y PSICOLÓGICOS

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    Artículo sobre la creación de un modelo que caracterice la violencia escolarEl objetivo de este trabajo fue analizar la relación entre las disfunciones familiares, la violencia escolar y algunos trastornos psicológicos, particularmente la depresión, la ansiedad y el estrés. Participaron 388 adolescentes mexicanos de entre 14 y 19 años de edad. Con la finalidad de examinar los efectos que tienen los factores familiares en la violencia escolar, así como las consecuencias de esta violencia en la salud mental de los adolescentes, se construyó un modelo de ecuaciones estructurales. Debido a que el modelo original no se ajustó de forma adecuada a los datos, se reespecificó mostrando de esta manera un ajuste global adecuado con los datos. Los resultados indican que los problemas en la comunicación y la falta de apoyo por parte de los padres fueron los dos predictores más significativos en la violencia escolar y la experiencia de victimización. Además, la depresión, el estrés y la ansiedad presentaron, de mayor a meno

    Autologous bone marrow expanded mesenchymal stem cells in patellar tendinopathy: protocol for a phase I/II, single-centre, randomized with active control PRP, double-blinded clinical trial

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    Introduction: Patellar tendon overuse injuries are common in athletes. Imaging may show a change in tissue structure with tendon thickening and disruption of the intratendinous substance. We wish to test the hypothesis that both autologous bone marrow expanded mesenchymal stem cells and autologous leukocyte-poor platelet-rich plasma (LP-PRP) implanted into the area of the disrupted tendinopathic patellar tendon will restore function, but tendon regeneration tissue will only be observed in the subjects treated with autologous bone marrow expanded mesenchymal stem cells. Methods and analysis: This is a single-centre, pilot phase I/II, double-blinded clinical trial with randomisation with active control. Twenty patients with a diagnosis of patellar tendinopathy with imaging changes (tendon thickening and disruption of the intratendinous substance at the proximal portion of the patellar tendon) will be randomised in a 1:1 ratio to receive a local injection of either bone-marrow autologous mesenchymal stem cells (MSC), isolated and cultured under GMP at The Institute of Biology and Molecular Genetics (IBGM) (Spain) or P-PRP. The study will have two aims: first, to ascertain whether a clinically relevant improvement after 3, 6 and 12 months according to the visual analogue scale (VAS), Victorian Institute of Sport Assessment for patellar tendons (VISA-P) and dynamometry scales (DYN) will be achieved; and second, to ascertain whether the proposed intervention will restore tendon structure as determined by ultrasonography (US), Doppler ultrasonography (DUS), and innovative MRI and ultrasound techniques: Magnetic Resonance T2 FAT SAT (UTE, Ultrashort Echo TE) sequence and Ultrasound Tissue Characterization (UTC). Patients who are randomised to the P-PRP treatment group but do not achieve a satisfactory primary endpoint after 6 months will be offered treatment with MSC

    Necesidades educativas de pacientes ambulatorios con diabetes tipo II atendidos en una Policlínica.

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    Introducción: La educación al diabéticoes una medida urgente para superar los altos índices de morbimortalidad asociados a la diabetes que enfrenta el mundo actualmente, siendo la caracterización sociodemográfica, clínica y farmacoterapéutica de este tipo de paciente un elemento importante para el éxito de estas actividades. Objetivo: Caracterizar desde el punto de vista sociodemográfico, clínico y farmacoterapéutico pacientes diabéticos ambulatorios atendidos en una Policlínica de Atención Farmacéutica Integral. Métodos: Se desarrolló un estudio descriptivo, de corte transversal y observacional, en 32 pacientes con diabetes tipo I y II, que acudían a los servicios de una Policlínica entre febrero del 2016 y diciembre del 2017. La muestra fue estimada por muestreo simple. El dato primario se obtuvo de entrevista estructurada, test de conocimiento y test de Morinsky-Green y procesado estadísticamente utilizando cálculo y comparación de porcentajes y test chi cuadrado (x2) para un nivel de significación de p≤0,05. Resultados: En la muestra prevaleció el sexo femenino (65.6%) entre 40 y 60 años (84.4%); el café fue el hábito más frecuente (62.5%), el consumo de carbohidratos (93.8%) el hábito dietético más común. Prevalecieron los pacientes con sobrepeso alto (65.6%) y niveles de glicemia (53.1%), colesterol (37.5%) y triglicéridos (46.9%) elevados. El 68.8% conocía poco sobre su enfermedad y tratamiento, así como el 53.1% fue no adherente a su tratamiento. Conclusiones: La caracterización sociodemográfica, clínica y farmacoterapéutica realizada apunta hacia la necesidad de brindar educación sanitaria a este grupo de pacientes para evitar complicaciones y mejorar su calidad de vida.

    The O3N2 and N2 abundance indicators revisited: improved calibrations based on CALIFA and Te-based literature data

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    The use of IFS is since recently allowing to measure the emission line fluxes of an increasingly large number of star-forming galaxies both locally and at high redshift. The main goal of this study is to review the most widely used empirical oxygen calibrations, O3N2 and N2, by using new direct abundance measurements. We pay special attention to the expected uncertainty of these calibrations as a function of the index value or abundance derived and the presence of possible systematic offsets. This is possible thanks to the analysis of the most ambitious compilation of Te-based HII regions to date. This new dataset compiles the Te-based abundances of 603 HII regions extracted from the literature but also includes new measurements from the CALIFA survey. Besides providing new and improved empirical calibrations for the gas abundance, we also present here a comparison between our revisited calibrations with a total of 3423 additional CALIFA HII complexes with abundances derived using the ONS calibration by Pilyugin et al. (2010). The combined analysis of Te-based and ONS abundances allows us to derive their most accurate calibration to date for both the O3N2 and N2 single-ratio indicators, in terms of all statistical significance, quality and coverage of the space of parameters. In particular, we infer that these indicators show shallower abundance dependencies and statistically-significant offsets compared to those of Pettini and Pagel (2004), Nagao et al. (2006) and P\'erez-Montero and Contini (2009). The O3N2 and N2 indicators can be empirically applied to derive oxygen abundances calibrations from either direct abundance determinations with random errors of 0.18 and 0.16, respectively, or from indirect ones (but based on a large amount of data) reaching an average precision of 0.08 and 0.09 dex (random) and 0.02 and 0.08 dex (systematic; compared to the direct estimations),respectively.Comment: 12 pages, 5 figures, accepted for publication in A&
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