LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain

Protein phosphatases are major regulators of signal transduction and they are involved in key cellular mechanisms such as proliferation, differentiation, and cell survival. Here we focus on one class of protein phosphatases, the type IIA Receptor-type Protein Tyrosine Phosphatases (RPTPs), or LAR-RPTP subfamily. In the last decade, LAR-RPTPs have been demonstrated to have great importance in neurobiology, from neurodevelopment to brain disorders. In vertebrates, the LAR-RPTP subfamily is composed of three members: PTPRF (LAR), PTPRD (PTPδ) and PTPRS (PTPσ), and all participate in several brain functions. In this review we describe the structure and proteolytic processing of the LAR-RPTP subfamily, their alternative splicing and enzymatic regulation. Also, we review the role of the LAR-RPTP subfamily in neural function such as dendrite and axon growth and guidance, synapse formation and differentiation, their participation in synaptic activity, and in brain development, discussing controversial findings and commenting on the most recent studies in the field. Finally, we discuss the clinical outcomes of LAR-RPTP mutations, which are associated with several brain disorders

Manual para processamento de pimentas (Capsicum spp) desidratada.

Introdução. Secagem de pimenta - Processo utilizado pelos produtores. Desidratação de pimenta - Secagem artificial em secador de cabine. Higiene e sanificação. Recomendações gerais para as etapas de processamento. Vantagens deste processo. Referências bibliográficas.bitstream/item/79988/1/doc63-2005.pd

Manual para a produção em pequena escala de conserva de tomate desidratado.

Higiene e sanitização. Fluxograma básico de processamento de tomate. Etapas de processamento de tomate seco. Elaboração de conserva de tomate. Etapas de processamento de conserva. Como estimar o lucro e os custos envolvidos no processamento.bitstream/item/65526/1/2003-DOC-0052.pd

Secagem como método de conservação de frutas.

Secagem como método de conservação: secagem natural x desidratação; tipos de secadores utilizados para frutas. Secadores de frutas desenvolvidos pela Embrapa Agroindústria de Alimentos: secador de frutas elétrico; secador de frutas solar; higiene no processamento de frutas. Processamento de frutas desidratadas: Banana; Uva; Ameixa; Pêssego; Figo; Abacaxi; Manga.bitstream/item/65529/1/2003-DOC-0054.pd

The Computational Power of Beeps

In this paper, we study the quantity of computational resources (state machine states and/or probabilistic transition precision) needed to solve specific problems in a single hop network where nodes communicate using only beeps. We begin by focusing on randomized leader election. We prove a lower bound on the states required to solve this problem with a given error bound, probability precision, and (when relevant) network size lower bound. We then show the bound tight with a matching upper bound. Noting that our optimal upper bound is slow, we describe two faster algorithms that trade some state optimality to gain efficiency. We then turn our attention to more general classes of problems by proving that once you have enough states to solve leader election with a given error bound, you have (within constant factors) enough states to simulate correctly, with this same error bound, a logspace TM with a constant number of unary input tapes: allowing you to solve a large and expressive set of problems. These results identify a key simplicity threshold beyond which useful distributed computation is possible in the beeping model.Comment: Extended abstract to appear in the Proceedings of the International Symposium on Distributed Computing (DISC 2015

Efecto de la coaplicación de herbicidas y adición de alperujo como enmienda en el comportamiento de diurón y terbutilazina en un suelo arcillo-limoso

Congreso celebrado del 21-24 de septiembre 2010, en Granada, España.Los herbicidas se aplican a los cultivos como formulaciones que habitualmente incluyen más de un principio activo. Sin embargo, los estudios sobre comportamiento de herbicidas en suelos en el laboratorio suelen hacerse aplicando los herbicidas de forma individual.Peer reviewe

Reliably Detecting Connectivity using Local Graph Traits

Local distributed algorithms can only gather sufficient information to identify local graph traits, that is, properties that hold within the local neighborhood of each node. However, it is frequently the case that global graph properties (connectivity, diameter, girth, etc) have a large influence on the execution of a distributed algorithm. This paper studies local graph traits and their relationship with global graph properties. Specifically, we focus on graph k-connectivity. First we prove a negative result that shows there does not exist a local graph trait which perfectly captures graph k-connectivity. We then present three different local graph traits which can be used to reliably predict the k-connectivity of a graph with varying degrees of accuracy. As a simple application of these results, we present upper and lower bounds for a local distributed algorithm which determines if a graph is k-connected. As a more elaborate application of local graph traits, we describe, and prove the correctness of, a local distributed algorithm that preserves k-connectivity in mobile ad hoc networks while allowing nodes to move independently whenever possible

Manual para construção de um secador de frutas.

Fases da montagem. Instruções para utilização do secador. Processamento de frutas desidratadas. Como estimar o lucro e os custos envolvidos na secagem. Relação do material para construção do secador.bitstream/item/33866/1/1997-DOC-0010.pdf2. ed. rev