SUSTAINABLE ENERGY ANALYSIS OF NIGERIAN ROAD TRANSPORTATION SECTOR: EFFECTS OF INFLUENCED FUEL DEMAND PATTERNS

Petrol and diesel utilisations in the Nigerian road transportation sector have been assessed, using exergy efficiency and improvement potential as parameters. The mean petrol engine exergy efficiency was 13.05%, while that of diesel engines was 10.79%. The average improvement potential of petrol engines was 2.07×1011 MJ, which was 75.6% of average input exergy. Diesel engines had an average improvement potential of 5.15×1010 MJ, which was 69.2% of average input exergy. Practical constancy of the exergy efficiencies of the engines left input exergy values as the sole determining factors of improvement potentials of the systems. Petrol fuel was found to be utilised, away from sustainable path, more than diesel fuel. This observation was found attributable to subsidisation of petrol downstream sector and simultaneous deregulation of the diesel downstream sector as well as the preponderance of petrol engines in the road transportation sector. In conclusion, it was recommended that a mechanism be put in place to check the unsustainable petrol fuel utilisation in the transport sector

Women Farmers’ Contributions to Maize Production in Afijio Local Government of Oyo State

The study investigated the contributions of women farmers to maize production in Afijio Local Government area, Oyo state. Multi-stage sampling technique was used to select 128 women farmers as sample size for the study. Data collected through interview schedule were analysed using frequency counts, percentages and mean while Pearson Product Moment Correlation and Chi-square were used to test the relationships that exist between selected socioeconomic characteristics and contributions of women farmers to maize production. Results revealed the mean age of respondents was 45years, 83.5% of respondents were married and 41.4% of the respondents had no formal education. High percentage of the respondents (82.5%) engaged in farming for both commercial and subsistence purposes, and activities such as, planting, fertilizer application, harvesting, processing, storage and marketing were performed by women farmers whereas ridging, land clearing and weeding were considered laborious and were usually contracted to hired labour. The results of Pearson Product Moment Correlation analysis showed that age (r = 0.950, P<0.05), farm size (r = 0.174, P<0.05), household size (r = 0.354, P<0.05) while the results of Chi-square analysis revealed that educational status (ᵡ2 =36.864 P<0.05), marital status (ᵡ2 =19.615, P<0.05) have significant association with contributions of women farmers to maize production in the study area. Hence, the study recommended that female education (through adult literacy) be intensified, young women be encouraged to be more involved in maize production, women should form themselves into group to learn techniques of trapping farm pests and in time of surplus, women maize farmers should form supply cooperatives to transport their produce to areas where it commands higher prices

Alpha-glucosidase and alpha-amylase inhibitory activities, molecular docking, and antioxidant capacities of plectranthus ecklonii constituents

Shortage in insulin secretion or degradation of produced insulin is the principal characteristic of the metabolic disorder of diabetes mellitus (DM). However, because the current medications for the treatment of DM have many detrimental side effects, it is necessary to develop more effective antidiabetic drugs with minimal side effects. Alpha-glucosidase and alpha-amylase inhibitors are directly implicated in the delay of carbohydrate digestion. Pharmacologically, these inhibitors could be targeted for the reduction in glucose absorption rate and, subsequently, decreasing the postprandial rise in plasma glucose and the risk for long-term diabetes complications. The main objectives of this research study were to isolate different phytochemical constituents present in the methanolic extract of Plectranthus ecklonii and evaluate their alpha-glucosidase and alpha-amylase inhibitory activities and antioxidant capacity

ASSESSMENT OF APPLICATION OF UNIVERSAL DESIGN PRINCIPLES IN EDUCATIONAL FACILITIES FOR CHALLENGED CHILDREN IN LAGOS STATE, NIGERIA

Lagos state Nigeria is one of the metropolitan and educationally advanced cities in Nigeria. Over the years the number of children with disabilities has been on the increase. Many of these challenged children are either denied the benefit of education or are constrained to attend schools which have not been designed to take care of their disabilities. Often times, such children are frustrated and their educational abilities are also negatively impacted. This has given use to schools which are now dedicated to challenged children. The aim of this study is to evaluate the design of these educational facilities in order to determine their application of universal design principles. The study is based on case study of schools for the challenged in Lagos state. Results indicate that many of the facilities did not conform to the universal design principles and consequently have affected learning of the children. The recommendation are made to enhance learning of challenged children through proper adoption of universal principals in planning of educational facilities. This is a novel study in Nigeria and its outcome will influence policy direction in the planning of educational facilities for challenged children in Nigeria and other developing countrie

An audit of surgical site infection following open prostatectomy in a Nigerian Teaching Hospital

Background: Surgical site infections (SSI) are a potential cause of morbidity and increased cost of care after operations such as open prostatectomy.Objective: To audit the occurrence of SSI after open prostatectomy at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, NigeriaMethods: A review of all patients who underwent open prostatectomy over a ten-year period (July 2005 to June 2015). Data analysis was done using the statistical package for social sciences version 21. Association between variables was determined using Chi-square or Fisher’s exact test as appropriate. A p-value < 0.05 was considered statistically significant.Results: A total of 247 open prostatectomy surgeries were reviewed, with the patients’ ages ranging from 43 – 91 years and a mean age of 67.0 ± 8.8 years. Elective procedures were 98.8% while the remaining 1.2% were emergency cases. There were 24 (9.8%) surgical site infections. The duration of admission of the patients with SSI ranged from 6 – 15 days with a mean of 9.5 ± 3.2 days, as against 4 – 9 days (mean of 5.0 ± 2.1days) for those without SSI. All the patients with SSI were successfully managed with no resultant mortality. Risk factors identified for SSI were emergency surgery (p=0.001), obesity (p<0.0001), diabetesmellitus (p=0.008), smoking (p<0.0001), pre-operative catheterization (p<0.0001), excessive haemorrhage (p<0.0001) and post-operative suprapubic bladder drainage (p<0.0001).Conclusion: SSI is a recognized complication of open prostatectomy. Identified risk factors for its occurrence from this audit are emergency operation, obesity, diabetes mellitus, smoking, pre-operative catheterization, excessive haemorrhage and post-operativesuprapubic bladder drainage. Age, approach to prostatectomy (retropubic vs transvesical), incision type (lower midline vs pfannenstiel), level of the surgeon, catheter type and modality of irrigation were however not significant risk factors for post-prostatectomy SSI in this study.Keywords: Surgical site infection, risk factors, open prostatectomy

Management of pelviureteric junction obstruction at a tertiary teaching hospital in southwestern Nigeria: A retrospective analysis of case records

Background: Pelviureteric junction obstruction (PUJO) is an important cause of upper urinary tract obstruction. It can cause marked impairment of renal function, especially in bilateral cases, if not diagnosed and treated promptly. Surgical intervention is currently the mainstay of treatment. We aimed to review the pattern of presentation and management outcomes of patients diagnosed with PUJO. Methods: We conducted a retrospective study of patients aged 2–60 years who presented with PUJO between January 2005 and December 2014. Demographic characteristics, clinical presentation, investigations, and treatment modalities were extracted from case notes. Data were analysed using SPSS version 20. Results: The age range of the 32 included PUJO patients was 2–60 years, with a median age of 30 years. Children constituted 31% of patients. There were 15 males and a male-to-female ratio of 0.88:1. Most PUJO was unilateral and left-sided (n = 19; 59%). Loin pain was the commonest symptom (n = 26; 81%), while 25% of patients had a urinary tract infection at presentation. All patients had normal renal function at the time of surgery, and Anderson–Hynes pyeloplasty was the most common technique employed (72% of cases). Postoperatively, the majority of patients (n = 31; 97%) had complete symptom resolution. Surgical site infection (n = 3; 9%) was the commonest postoperative complication, and the median hospital stay was 11 days. There was no mortality. Conclusions: Most patients with PUJO presented late. Most of our patients underwent Anderson–Hynes pyeloplasty with satisfactory outcomes. Keywords: pelviureteric junction obstruction; PUJO; loin pain; Anderson–Hynes pyeloplasty; Foley Y-V plasty; Nigeria

The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus

Searching for new natural bioactive capping agents represent an urgent priority in the green synthesis of metal nanoparticles. Additionaly, the biosaftey of metal nanparticles is a major concern especially in medical applications. Recently, the use of pharmacollogicaly active natural products as capping agents has been deployed to avoid toxic effects during the nanoparticles preparation and to enhance their drugability compared with convential drugs. Helichrysum foetidum is a South African medicinal plant used in folk medicine for the treatment of different human pathologies, and it is known to contain a variety of bioactive compounds. Herein, the total extract and two pure chalcones, helichrysetin and helichrysin, isolated from the same plant were successfully used to synthesize quasi-monodispersed gold nanoparticles in the size range of 2–12 nm. The bio-evaluation of samples indicated that the AuNP/capping agent conjugates are biostable, and have different biological profiles from the total extract/pure compounds. The enzymatic inhibition assays showed significant inhibition by the total extract, helichrysetin and their gold nanoparticles. Interestingly, a similar activity was observed for glucose uptake in HEK293 treated cells. On the other hand, all the tested samples relatively demonstrated no cytotoxicity when tested against the HaCaT keratinocytes. In conclusion, the study demonstrated potential enhancement of glucose uptake in mammalian kidney cells, and inhibition of carbohydrate-hydrolysing enzymes by green synthesized gold nanoparticles of H. foetidum. It also provides a therapeutic appraisal of AuNPs/chalcones conjugate towards the development of antidiabetes drugs derived from H. foetidum and its gold nanoparticles

An audit of surgical site infection following open prostatectomy in a Nigerian Teaching Hospital

Background: Surgical site infections (SSI) are a potential cause of morbidity and increased cost of care after operations such as open prostatectomy. Objective: To audit the occurrence of SSI after open prostatectomy at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria Methods: A review of all patients who underwent open prostatectomy over a ten-year period (July 2005 to June 2015). Data analysis was done using the statistical package for social sciences version 21. Association between variables was determined using Chi-square or Fisher\u2019s exact test as appropriate. A p-value < 0.05 was considered statistically significant. Results: A total of 247 open prostatectomy surgeries were reviewed, with the patients\u2019 ages ranging from 43 \u2013 91 years and a mean age of 67.0 \ub1 8.8 years. Elective procedures were 98.8% while the remaining 1.2% were emergency cases. There were 24 (9.8%) surgical site infections. The duration of admission of the patients with SSI ranged from 6 \u2013 15 days with a mean of 9.5 \ub1 3.2 days, as against 4 \u2013 9 days (mean of 5.0 \ub1 2.1days) for those without SSI. All the patients with SSI were successfully managed with no resultant mortality. Risk factors identified for SSI were emergency surgery (p=0.001), obesity (p<0.0001), diabetes mellitus (p=0.008), smoking (p<0.0001), pre-operative catheterization (p<0.0001), excessive haemorrhage (p<0.0001) and post-operative suprapubic bladder drainage (p<0.0001). Conclusion: SSI is a recognized complication of open prostatectomy. Identified risk factors for its occurrence from this audit are emergency operation, obesity, diabetes mellitus, smoking, pre-operative catheterization, excessive haemorrhage and post-operative suprapubic bladder drainage. Age, approach to prostatectomy (retropubic vs transvesical), incision type (lower midlinevs pfannenstiel), level of the surgeon, catheter type and modality of irrigation were however not significant risk factors for post-prostatectomy SSI in this study. DOI: https://dx.doi.org/10.4314/ahs.v19i2.30 Cite as: Salako AA, Badmus TA, Onyia CU, David RA, Adejare IE, Lawal AO, Onyeze CI, Ndegbu CU. An audit of surgical site infection following open prostatectomy in a Nigerian Teaching Hospital. Afri Health Sci.2019;19(2): 2068-2072. https://dx.doi.org/10.4314/ahs.v19i2.3

Delivering safe and effective test-result communication, management and follow-up : a mixed-methods study protocol

Introduction: The failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. The objective of this project is to: (1) improve the effectiveness and safety of test-result management through the establishment of clear governance processes of communication, responsibility and accountability; (2) harness health information technology (IT) to inform and monitor test-result management; (3) enhance the contribution of consumers to the establishment of safe and effective test-result management systems. Methods and analysis: This convergent mixed-methods project triangulates three multistage studies at seven adult hospitals and one paediatric hospital in Australia. Study 1 adopts qualitative research approaches including semistructured interviews, focus groups and ethnographic observations to gain a better understanding of test-result communication and management practices in hospitals, and to identify patient-safety risks which require quality-improvement interventions. Study 2 analyses linked sets of routinely collected healthcare data to examine critical test-result thresholds and test-result notification processes. A controlled before-and-after study across three emergency departments will measure the impact of interventions (including the use of IT) developed to improve the safety and quality of test-result communication and management processes. Study 3 adopts a consumer-driven approach, including semistructured interviews, and the convening of consumer-reference groups and community forums. The qualitative data will identify mechanisms to enhance the role of consumers in test-management governance processes, and inform the direction of the research and the interpretation of findings. Ethics and dissemination: Ethical approval has been granted by the South Eastern Sydney Local Health District Human Research Ethics Committee and Macquarie University. Findings will be disseminated in academic, industry and consumer journals, newsletters and conferences