Epidemiological Analysis of Oral Surgery Procedures

The epidemiological study was conducted to assess oral health of patients referred to the Department of Oral Surgery at Clinical Hospital Center in Rijeka. The distribution of particular diagnoses and surgical interventions in relation to frequency of occurrence was tested. The total of 1,268 patients aged from 5 to 89 years, both sexes, were included in the study. All the patients were treated under local anesthesia. The most common reason for referral to oral surgery was chronic periapical lesion (33.3%), followed by retained root (26.7%), impacted tooth (12.7%), and radicular cyst (8.3%). The majority of patients, residents of Rijeka city area, were treated for the diagnosis of adult periodontitis, while the radicular cysts and hypertrophy of the upper frenulum were more frequent referral diagnoses in patients coming from the areas around Rijeka. Extractions were performed more frequently in patients from Rijeka, while cystectomies with apicectomies and frenulectomies in other patients

Trace Element (TE) Release from Two Different Base Alloys Unde Conditions Imitating Oral Saliva

Electrochemical conditions in the oral cavity lead to a release of metal ions into the patient\u27s saliva. The aim of this study was to examine and compare the types andquantities of metal ions released from two base alloys: Co-Cr-Mo alloy (WironitR, Bego, Germany) and Ni-Cr alloy (Wiron 99, Bego, Germany) under in vitro conditions imitating artificial saliva. We soaked ten sets of each alloy having 497 mm2 exposure surface for 1, 2, 3, 4, 5, 6, 7, 14, 21 and 30 days (six pieces each set) in phosphate buffered saline (pH 6.0). TE in the phosphate buffered saline (saliva) were assessed by ICP-AES (JY 50P, Jobin-Ywon, France) with the detection limit of 10 mg/L. We found detectable amounts (mg/L) of TE (Mean SD) released from Co-Cr-Mo alloy (Mean SD): Co 337 (170), Fe 21 (15) Zn 87 (56), Ni 41 (68), and Cr 49 (42) and detectable amounts of TE released from Ni-Cr alloy (Mean SD): Co 265 (300), Fe 247 (256) Zn 92 (46), Ni 542 (668), and Cr 396 (410). The manufacturer did not indicate the presence of Fe, Zn, and Ni in the Co-Cr-Mo alloy and the presence of Fe, Co and Zn, in the Ni-Cr alloy. A significantly higher amount of Fe, Ni and Cr was released from Ni-Cr alloy (p<0.05), and a considerably higher amount of Co was released from Co-Cr-Mo alloy, although it did not reach a statistically significant level (p>0.05), while there was no significant difference between the two alloys for Fe ion release (p>0.05). We must keep in mind that the amount of the released TE may be much higher than the reported values in this study, after the laboratory procedures (casting, polishing, etc.) and allergenic essential TE Cr, Co, and Ni may be present locally in a considerably higher amount

The Satisfaction with the Removable Partial Denture Therapy in the Croatian Adult Population

Little is known about the outcomes of treatment and patient’s satisfaction with removable partial dentures in adult Croatian population. Therefore patient’s satisfaction with their partial dentures in relation to some socio-economic variables was studied. Patient’s satisfaction with denture retention, speech, aesthetics, comfort of wearing dentures, chewing ability was also studied in relation to different denture classification, construction, material, denture base shape (major connectors), denture support and the number of missing teeth. A total of 165 patients, 59 males and 105 females between 38 and 87 years took part in this study. A questionnaire, devised for a purpose of the study, was divided into three parts. In the first part, patients answered questions about age, gender, marital status, education, general health, socio-economic status, self-supporting life, period of tooth loss and number of previous denture experiences and in the second part, patients graded their partial dentures, depending on the level of satisfaction, by using a scale from 1 to 5. In the third part a dentist determined Kennedy classification and their modifications, denture material and denture support, denture base shape and the number of missing teeth and graded a denture construction. Influence of these factors on patient’s satisfaction was analyzed. A majority of the examined patients were satisfied with the partial prosthesis, but a small amount of dissatisfaction existed. More then half of them scored all the examined parameters to the best score category. Considering chewing with lower partial dentures, women were more satisfied than men (p <0.05). Patients with more missing teeth gave lower grades for the comfort of wearing dentures (p<0.05). Patients of higher education gave lower grades (p<0.05) for the aesthetics. Patients were not satisfied with speech if the dentist graded a construction of alower partial denture low (p<0.05). Dissatisfaction was related to mastication, aesthetics, number of missing teeth and ability of speech. These findings can aid a clinician in discussing a treatment plan and help a patient understand the risk of dissatisfaction in the presence of certain factors

Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors

Contains fulltext : 88032.pdf (publisher's version ) (Closed access)INTRODUCTION: In cancer, an extracellular and membrane bound localization of cathepsins contribute to the invasion of tumor cells at the basement membrane. METHODS: This is the first study that explored levels of cathepsins B (CatB), L (CatL) and their inhibitor cystatin C (CysC) in the cystic fluid (CF) of ovarian tumors (n = 110). RESULTS: CF contained considerable amounts of CatB, CatL and CysC. Remarkable differences in CatB and CatL and CysC CF levels were found between different histopathological tumor subtypes. Levels of CatB and CysC were significantly higher in CF of malignant serous tumors compared to those found in benign serous tumors (p = 0.010 and p = 0.001 respectively), whereas levels of CatL were significantly higher in CF of malignant mucinous tumors compared to those found in benign mucinous tumors (p = 0.035). CatB and CysC showed a strong correlation in the group of patients with malignant serous tumors (p < 0.001; R = 0.921) suggesting that the increase in CatB might be balanced by a corresponding increase in CysC. CONCLUSION: Further studies are warranted to investigate cathepsins as possible prognostic biomarkers for the aggressiveness of ovarian cancer.1 mei 201