2,088 research outputs found

    Semiparametric Cross Entropy for rare-event simulation

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    The Cross Entropy method is a well-known adaptive importance sampling method for rare-event probability estimation, which requires estimating an optimal importance sampling density within a parametric class. In this article we estimate an optimal importance sampling density within a wider semiparametric class of distributions. We show that this semiparametric version of the Cross Entropy method frequently yields efficient estimators. We illustrate the excellent practical performance of the method with numerical experiments and show that for the problems we consider it typically outperforms alternative schemes by orders of magnitude

    Urothelial TRPV1: TRPV1-Reporter Mice, a Way to Clarify the Debate?

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    A commentary on Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cell

    Antenna subtraction with massive fermions at NNLO: Double real initial-final configurations

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    We derive the integrated forms of specific initial-final tree-level four-parton antenna functions involving a massless initial-state parton and a massive final-state fermion as hard radiators. These antennae are needed in the subtraction terms required to evaluate the double real corrections to ttˉt\bar{t} hadronic production at the NNLO level stemming from the partonic processes qqˉ→ttˉq′qˉ′q\bar{q}\to t\bar{t}q'\bar{q}' and gg→ttˉqqˉgg\to t\bar{t}q\bar{q}.Comment: 24 pages, 1 figure, 1 Mathematica file attache

    Gating-by-tilt of mechanosensitive membrane channels

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    We propose an alternative mechanism for the gating of biological membrane channels in response to membrane tension that involves a change in the slope of the membrane near the channel. Under biological membrane tensions we show that the energy difference between the closed (tilted) and open (untilted) states can far exceed kBT and is comparable to what is available under simple ilational gating. Recent experiments demonstrate that membrane leaflet asymmetries (spontaneous curvature) can strong effect the gating of some channels. Such a phenomenon would be more easy to explain under gating-by-tilt, given its novel intrinsic sensitivity to such asymmetry.Comment: 10 pages, 2 figure

    Precise predictions for WH+jet production at the LHC

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    We present precise predictions for the production of a Higgs boson in association with a hadronic jet and a W boson at hadron colliders. The behaviour of QCD corrections are studied for fiducial cross sections and distributions of the charged gauge boson and jet-related observables. The inclusive process (at least one resolved jet) and the exclusive process (exactly one resolved jet) are contrasted and discussed. The inclusion of QCD corrections up to O(α3s)leads to a clear stabilisation of the predictions and contributes substantially to a reduction of remaining theoretical uncertaintie

    VH + jet production in hadron-hadron collisions up to order α3s in perturbative QCD

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    We present precise predictions for the hadronic production of an on-shell Higgs boson in association with a leptonically decaying gauge boson and a jet up to order α3s. We include the complete set of NNLO QCD corrections to both charged- and neutral-current Drell-Yan type contributions, as well as the previously known leading heavy quark loop induced contributions which involve a direct Higgs-quark coupling. As an application, we study a range of differential observables in proton-proton collisions at s√ = 13 TeV for both the charged- and neutral-current production modes. For each Higgs production process, we assess the improvement in the theoretical uncertainty for both the exclusive (njet = 1) and inclusive (njet ≥ 1) jet categories. We find that the inclusion of the NNLO corrections to the Drell-Yan type contributions is essential in stabilising the predictions and in reducing the theoretical uncertainty for both inclusive and exclusive jet production for all three modes. This is particularly true in the kinematical regimes associated with low to medium values of the transverse momentum of the produced vector boson and where the differential cross sections are the largest. For the neutral-current process, we find that the heavy quark loop induced contributions have their largest phenomenological impact (an increase in the size of the NNLO corrections, a distortion of the distribution shape and an enlargement of the left over remaining uncertainties) in kinematical regions associated to large values of pT,Z (typically above 150 GeV) where the cross sections are smaller

    Predictions for Z-Boson Production in Association with a b-Jet at O(αs3)

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    Precise predictions are provided for the production of a Z boson and a b-jet in hadron-hadron collisions within the framework of perturbative QCD, at O(α3s). To obtain these predictions, we perform the first calculation of a hadronic scattering process involving the direct production of a flavored jet at next-to-next-to-leading-order accuracy in massless QCD and extend techniques to also account for the impact of finite heavy-quark mass effects. The predictions are compared to CMS data obtained in pp collisions at a center-of-mass energy of 8 TeV, which are the most precise data from run I of the LHC for this process, where a good description of the data is achieved. To allow this comparison, we have performed an unfolding of the data, which overcomes the long-standing issue that the experimental and theoretical definitions of jet flavor are incompatible

    Acoustic oscillations in stars near the tip of the red giant branch

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    Small amplitude oscillations are observed in red giant branch (RGB) stars. Data on such oscillations are a source of information about the objects, notably about properties of convection in their envelopes and about the systems these objects inhabit. The OGLE-III catalog contains data for about 80 thousand small amplitude variable red giants (OSARGs) in the Large Magellanic Cloud. We want to explain variability in OSARGs as the solar-like oscillation and to associate the peaks in power spectra with frequencies of acoustic modes. We use data on reddening-free magnitudes of the objects and interpret them in terms of stellar physical parameters using tabulated isochrones calculated for ages and composition parameters corresponding to the upper RGB of the LMC. Massive data on the peak frequencies and amplitudes are compared with expectations for stochastically excited oscillations. The frequencies are also compared with those calculated for radial modes in envelope models with parameters taken from the isochrones. In stars close to the tip of the RGB, the peaks in power spectra are found in the 0.1-1.0 μ\muHz range, which is consistent with extrapolation of the frequency-luminosity relation for the solar-like oscillation. The dominant peaks occur close to the first two radial overtones. The increase in amplitude with luminosity is slower than linear. The exponent s=0.9 is similar to what is found from recent analysis of CoRoT data on less luminous red giants. Frequency separations between dominant peaks are found to be smaller by about 20% than calculated separations between these modes. After examining various possibilities, we left this discrepancy unexplained. The small amplitude variability of stars at the RGB tip is likely to be caused by a stochastic excitation of acoustic oscillations, but interpreting of individual peaks in power spectra presents a problem.Comment: Accepted for publication in Astronomy and Astrophysics, 6 pages, 6 figure
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