Socioeconomics determinants of household carbon footprint in Iskandar Malaysia

Understanding the complex links between socioeconomic variables and carbon emissions can reveal household spending and lifestyle patterns. This study oversees those issues and examines consumption patterns and their related variables such as climate change understanding, attitudes, and knowledge, in order to better comprehend the complicated linkages. This study revealed that eight socioeconomic elements influence a household’s carbon footprint: (i) household income (β = 0.476, p < 0.05), (ii) green attitudes (β = − 0.196, p < 0.05), (iii) residential space (β = 0.157, p < 0.05), (iv), education levels (β = 0.131, p < 0.05), (v) household’s tenure status by ownership (β = 0.130, p < 0.05), (vi) household’s age (β = 0.112, p < 0.05), (vii) size of household (β = 0.101, p < 0.05), and, (viii) female-headed household (β = − 0.077, p < 0.05). Approximately 83.6% of respondents are mindful of climate change, but only 2.6% correctly define it as a long-term shift in weather patterns. The study found that 82% of households are willing to change their consumption habits and lifestyle to reduce their household’s carbon footprint. In order to achieve a low carbon society, our research advocate a multipronged approach and policy action is crucial based on the results. Further, robust climate change educational and awareness programmes is decisive at the multilevel and scale in Malaysia to achieve its carbon emissions reduction target by 2050

Perception and practice of Kangaroo Mother Care after discharge from hospital in Kumasi, Ghana: A longitudinal study

BACKGROUND: The practice of Kangaroo Mother Care (KMC) is life saving in babies weighing less than 2000 g. Little is known about mothers' continued unsupervised practice after discharge from hospitals. This study aimed to evaluate its in-hospital and continued practice in the community among mothers of low birth weight (LBW) infants discharged from two hospitals in Kumasi, Ghana. METHODS: A longitudinal study of 202 mothers and their inpatient LBW neonates was conducted from November 2009 to May 2010. Mothers were interviewed at recruitment to ascertain their knowledge of KMC, and then oriented on its practice. After discharge, the mothers reported at weekly intervals for four follow up visits where data about their perceptions, attitudes and practices of KMC were recorded. A repeated measure logistic regression analysis was done to assess variability in the binary responses at the various reviews visits. RESULTS: At recruitment 23 (11.4%, 95%CI: 7.4 to 16.6%) mothers knew about KMC. At discharge 95.5% were willing to continue KMC at home with 93.1% willing to practice at night. 95.5% thought KMC was beneficial to them and 96.0% beneficial to their babies. 98.0% would recommend KMC to other mothers with 71.8% willing to practice KMC outdoors.At first follow up visit 99.5% (181) were still practicing either intermittent or continuous KMC. This proportion did not change significantly over the four weeks (OR: 1.4, 95%CI: 0.6 to 3.3, p-value: 0.333). Over the four weeks, increasingly more mothers practiced KMC at night (OR: 1.7, 95%CI: 1.2 to 2.6, p = 0.005), outside their homes (OR: 2.4, 95%CI: 1.7 to 3.3, p < 0.001) and received spousal help (OR: 1.6, 95%CI: 1.1 to 2.4, p = 0.007). Household chores and potentially negative community perceptions of KMC did not affect its practice with odds of 0.8 (95%CI: 0.5 to 1.2, p = 0.282) and 1.0 (95%CI: 0.6 to 1.7, p = 0.934) respectively. During the follow-up period the neonates gained 23.7 sg (95%CI: 22.6 g to 24.7 g) per day. CONCLUSION: Maternal knowledge of KMC was low at outset. Once initiated mothers continued practicing KMC in hospital and at home with their infants gaining optimal weight. Continued KMC practice was not affected by perceived community attitudes

Genome-Wide Association Study Identifies Chromosome 10q24.32 Variants Associated with Arsenic Metabolism and Toxicity Phenotypes in Bangladesh

Arsenic contamination of drinking water is a major public health issue in many countries, increasing risk for a wide array of diseases, including cancer. There is inter-individual variation in arsenic metabolism efficiency and susceptibility to arsenic toxicity; however, the basis of this variation is not well understood. Here, we have performed the first genome-wide association study (GWAS) of arsenic-related metabolism and toxicity phenotypes to improve our understanding of the mechanisms by which arsenic affects health. Using data on urinary arsenic metabolite concentrations and approximately 300,000 genome-wide single nucleotide polymorphisms (SNPs) for 1,313 arsenic-exposed Bangladeshi individuals, we identified genome-wide significant association signals (P<5×10−8) for percentages of both monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) near the AS3MT gene (arsenite methyltransferase; 10q24.32), with five genetic variants showing independent associations. In a follow-up analysis of 1,085 individuals with arsenic-induced premalignant skin lesions (the classical sign of arsenic toxicity) and 1,794 controls, we show that one of these five variants (rs9527) is also associated with skin lesion risk (P = 0.0005). Using a subset of individuals with prospectively measured arsenic (n = 769), we show that rs9527 interacts with arsenic to influence incident skin lesion risk (P = 0.01). Expression quantitative trait locus (eQTL) analyses of genome-wide expression data from 950 individual's lymphocyte RNA suggest that several of our lead SNPs represent cis-eQTLs for AS3MT (P = 10−12) and neighboring gene C10orf32 (P = 10−44), which are involved in C10orf32-AS3MT read-through transcription. This is the largest and most comprehensive genomic investigation of arsenic metabolism and toxicity to date, the only GWAS of any arsenic-related trait, and the first study to implicate 10q24.32 variants in both arsenic metabolism and arsenical skin lesion risk. The observed patterns of associations suggest that MMA% and DMA% have distinct genetic determinants and support the hypothesis that DMA is the less toxic of these two methylated arsenic species. These results have potential translational implications for the prevention and treatment of arsenic-associated toxicities worldwide

Arsenic metabolism efficiency has a causal role in arsenic toxicity: Mendelian randomization and gene-environment interaction

Background Arsenic exposure through drinking water is a serious global health issue. Observational studies suggest that individuals who metabolize arsenic efficiently are at lower risk for toxicities such as arsenical skin lesions. Using two single nucleotide polymorphisms (SNPs) in the 10q24.32 region (near AS3MT) that show independent associations with metabolism efficiency, Mendelian randomization can be used to assess whether the association between metabolism efficiency and skin lesions is likely to be causal

Global report on preterm birth and stillbirth (4 of 7): delivery of interventions

<p>Abstract</p> <p>Background</p> <p>The efficacious interventions identified in the previous article of this report will fail unless they are delivered at high and equitable coverage. This article discusses critical delivery constraints and strategies.</p> <p>Barriers to scaling up interventions</p> <p>Achieving universal coverage entails addressing major barriers at many levels. An overarching constraint is the lack of political will, resulting from the dearth of preterm birth and stillbirth data and the lack of visibility. Other barriers exist at the household and community levels, such as insufficient demand for interventions or sociocultural barriers; at the health services level, such as a lack of resources and trained healthcare providers; and at the health sector policy and management level, such as poorly functioning, centralized systems. Additional constraints involve weak governance and accountability, political instability, and challenges in the physical environment.</p> <p>Strategies and examples</p> <p>Scaling up maternal, newborn and child health interventions requires strengthening health systems, but there is also a role for focused, targeted interventions. Choosing a strategy involves identifying appropriate channels for reaching high coverage, which depends on many factors such as access to and attendance at healthcare facilities. Delivery channels vary, and may include facility- and community-based healthcare providers, mass media campaigns, and community-based approaches and marketing strategies. Issues related to scaling up are discussed in the context of four interventions that may be given to mothers at different stages throughout pregnancy or to newborns: (1) detection and treatment of syphilis; (2) emergency Cesarean section; (3) newborn resuscitation; and (4) kangaroo mother care. Systematic reviews of the literature and large-scale implementation studies are analyzed for each intervention.</p> <p>Conclusion</p> <p>Equitable and successful scale-up of preterm birth and stillbirth interventions will require addressing multiple barriers, and utilizing multiple delivery approaches and channels. Another important need is developing strategies to discontinue ineffective or harmful interventions. Preterm birth and stillbirth interventions must also be placed in the broader maternal, newborn and child health context to identify and prioritize those that will help improve several outcomes at the same time. The next article discusses advocacy challenges and opportunities.</p

Perineal musculature in the Black Bengal goat

With the aim of preparing topographic descriptions and illustrations of the perineaj muscles of the black Bengal does, 12 adult animals were used. The animals were anaesthetized and bled to death by giving incision on the right common carotid artery. Whole vascular system was flashed with 0.85% physiological saline solution and then 10% formalin was injected through the same route for well preservation. After preservation, the muscles of the perineum were surgically isolated, transected and studied. It revealed that muscles of the pelvic diaphragm were M. levator ani and M. coccygeus. The M. levator ani was originated entirely from the sacrosciatic ligament and M. coccygeus from the medial side of the ischiatic spine and from the inside of the sacrotuberal ligament. M. levator ani was poorly developed and was blended with coccygeus for some distance at their insertion. Muscles of the urogenital diaphragm were M. urethralis, M. ischiourethralis and M. bulboglandularis. M. bulboglandularis was a small circular muscle which enclosed the major vestibular gland. Anal musculature of the perineum were M. sphincter ani externus, M. rectococcygeus and M. rectractor clitoridis. M. sphincter ani externus completely encircled the anus. Its fibers crossed ventral to the anus and continued into the opposite labium and the labium on the same side. M. rectococcygeus inserted on the ventral surface of the 5th and 6th caudal vertebrae. M. retractor clitoridis was originated from the 3rd and 4th caudal vertebrae. Urogenital musculature of the perineum were M: transverses perinei superficialis, M. constrictor vestibuli and M. constrictor vulvae. M. constrictor vestibuli covered the ventrolateral surface of the vestibule. M. constrictor vulvae was continuous, with external anal sphincter at the decussation. The overall findings of this work will be helpful for the veterinarians, veterinary students, teachers and research personnel in the relevant technical fields

Bangladesh country report: pro-poor intervention strategies in irrigated agriculture in Asia: poverty in irrigated agriculture: issues and options

Q. K. Ahmad, Zahurul Karim, Khandaker Azharul Haq, Abul Quasem, Khalilur Rahman, Nityananda Chakravorty, Noajesh Ali, Rowshan Akhter, Mohammad Zubair Hasan, A. F. Younus, Afzal Hossain, M. A. Karim, S.M. Hossain Siddiqui Newaz Khoshbu Ahme

Managerial belief in Corporate Responsibility, and perceived business benefits and challenges

Little research has been done on the microfoundations of engagement on CR on an international basis. This research describes the result of an empirical study of the business benefits of CR based on a sample of senior managers’ perceptions of companies across several countries. Findings highlight a positive relationship between corporate CR values and a range of business benefits, including productivity and profitability. This article reveals a positive relationship between CR values held by individual executives and their perception of their employer’s CR values. Further, this study reveals a positive relationship between firm CR values and perceived business benefits, including productivity and profitability. In addition, it highlights a range of challenges executives see as hampering the engagement with CR, and thereby the potential loss of greater business benefits