1,338 research outputs found
Thermal testing by internal IR heating of the FEP module
A spacecraft module, to be integrated with the FLTSATCOM spacecraft, was tested in a simulated orbit environment separate from the host spacecraft. Thermal vacuum testing of the module was accomplished using internal IR heating rather than conventional external heat sources. For this configuration, the technique produced boundary conditions expected for flight to enable verification of system performance and thermal design details
Comment on "Peierls Gap in Mesoscopic Ring Threated by a Magnetic Flux"
In a recent letter, Yi et al. PRL 78, 3523 (1997), have considered the
stability of a Charge Density Wave in a one-dimensional ring, in the presence
of an Aharonov-Bohm flux. This comment shows that, in one dimension, the
stability of the Charge Density Wave depends on the parity of the number of
electrons in the ring. This effect is similar to the parity effect known for
the persistent current in one-dimensional rings.Comment: Latex, 1 page, 2 figure
Understanding the relationship between mothersâ attitudes toward television and childrenâs television exposure: A longitudinal study of reciprocal patterns and the moderating role of maternal stress
This two-wave panel study among mothers (N = 508) of children between ages six months and six years investigated a) the possibility of a reciprocal relationship between mothersâ attitudes toward television and childrenâs television viewing, and b) the conditional probability of this reciprocal relationship. Two-wave multigroup cross-lagged analyses provided evidence for reciprocal patterns that depend on the level of maternal stress. The findings indicated that mothersâ attitudes toward television predicted childrenâs subsequent television viewing among non-stressed mothers, but not among stressed mothers. Childrenâs television viewing predicted mothersâ subsequent negative attitudes toward television among stressed mothers, but not among non-stressed mothers. Implications for the role of parentsâ attitudes regarding childrenâs television viewing are discussed
Sums of products of Ramanujan sums
The Ramanujan sum is defined as the sum of -th powers of the
primitive -th roots of unity. We investigate arithmetic functions of
variables defined as certain sums of the products
, where are polynomials with
integer coefficients. A modified orthogonality relation of the Ramanujan sums
is also derived.Comment: 13 pages, revise
Algebras generated by two bounded holomorphic functions
We study the closure in the Hardy space or the disk algebra of algebras
generated by two bounded functions, of which one is a finite Blaschke product.
We give necessary and sufficient conditions for density or finite codimension
of such algebras. The conditions are expressed in terms of the inner part of a
function which is explicitly derived from each pair of generators. Our results
are based on identifying z-invariant subspaces included in the closure of the
algebra. Versions of these results for the case of the disk algebra are given.Comment: 22 pages ; a number of minor mistakes have been corrected, and some
points clarified. Conditionally accepted by Journal d'Analyse Mathematiqu
Mutually unbiased bases: tomography of spin states and star-product scheme
Mutually unbiased bases (MUBs) are considered within the framework of a
generic star-product scheme. We rederive that a full set of MUBs is adequate
for a spin tomography, i.e. knowledge of all probabilities to find a system in
each MUB-state is enough for a state reconstruction. Extending the ideas of the
tomographic-probability representation and the star-product scheme to
MUB-tomography, dequantizer and quantizer operators for MUB-symbols of spin
states and operators are introduced, ordinary and dual star-product kernels are
found. Since MUB-projectors are to obey specific rules of the star-product
scheme, we reveal the Lie algebraic structure of MUB-projectors and derive new
relations on triple- and four-products of MUB-projectors. Example of qubits is
considered in detail. MUB-tomography by means of Stern-Gerlach apparatus is
discussed.Comment: 11 pages, 1 table, partially presented at the 17th Central European
Workshop on Quantum Optics (CEWQO'2010), June 6-11, 2010, St. Andrews,
Scotland, U
Classical information deficit and monotonicity on local operations
We investigate classical information deficit: a candidate for measure of
classical correlations emerging from thermodynamical approach initiated in
[Phys. Rev. Lett 89, 180402]. It is defined as a difference between amount of
information that can be concentrated by use of LOCC and the information
contained in subsystems. We show nonintuitive fact, that one way version of
this quantity can increase under local operation, hence it does not possess
property required for a good measure of classical correlations. Recently it was
shown by Igor Devetak, that regularised version of this quantity is monotonic
under LO. In this context, our result implies that regularization plays a role
of "monotoniser".Comment: 6 pages, revte
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma.
Cross-talk among oncogenic signaling and metabolic pathways may create opportunities for new therapeutic strategies in cancer. Here we show that although acute inhibition of EGFR-driven glucose metabolism induces only minimal cell death, it lowers the apoptotic threshold in a subset of patient-derived glioblastoma (GBM) cells. Mechanistic studies revealed that after attenuated glucose consumption, Bcl-xL blocks cytoplasmic p53 from triggering intrinsic apoptosis. Consequently, targeting of EGFR-driven glucose metabolism in combination with pharmacological stabilization of p53 with the brain-penetrant small molecule idasanutlin resulted in synthetic lethality in orthotopic glioblastoma xenograft models. Notably, neither the degree of EGFR-signaling inhibition nor genetic analysis of EGFR was sufficient to predict sensitivity to this therapeutic combination. However, detection of rapid inhibitory effects on [18F]fluorodeoxyglucose uptake, assessed through noninvasive positron emission tomography, was an effective predictive biomarker of response in vivo. Together, these studies identify a crucial link among oncogene signaling, glucose metabolism, and cytoplasmic p53, which may potentially be exploited for combination therapy in GBM and possibly other malignancies
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