251 research outputs found
Deployable antenna phase A study
Applications for large deployable antennas were re-examined, flight demonstration objectives were defined, the flight article (antenna) was preliminarily designed, and the flight program and ground development program, including the support equipment, were defined for a proposed space transportation system flight experiment to demonstrate a large (50 to 200 meter) deployable antenna system. Tasks described include: (1) performance requirements analysis; (2) system design and definition; (3) orbital operations analysis; and (4) programmatic analysis
Pengembangan E-Modul Matematika Pada Materi Pecahan
This research aims to produce learning resources in the form of mathematics e-modules to be tested for eligibility in students of grade IV SDN 2 Batujai. The type of research used in research is development research with 4d models (Define, Design, Develop, and Disseminate). The subjects used in this study were teachers and students of grade IV at SDN 2 Batujai which numbered 29 people. The results showed that learning resources in the form of e-module mathematics already met the criteria worthy by obtaining a percentage of 79,7% of material experts and 85% of media experts. Teacher response and student response showed that the mathematics e-modules were feasible to use with 82,5% of teacher responses and 84,2 % of student responses. Based on the data it can be concluded that e-module mathematics fractional material is suitable for use as a source of learning that can be used by students and teacher
Born on 19 November 1912: he, George Palade, a man who contributed so much to the progress of modern cell biology
In his 1971 paper George Palade wrote for Albert Claude, the founder of biological electron microscopic method: “Seldom has a field owed so much to a single man”. Herein, we articulate the same words for George Palade, the Teacher of many generations in cell biology research and education. Herein we focus on the paradigm shifts in the cell biology, namely the transition from light to transmission electron microscopy in studying cell protein secretion made by George Palade. Onward, we discuss on the transition from contractile to secretory phenotype of vascular smooth muscle cells initiated by Maria Daria Haust and developed by our research group. Taken together, we argue that one of the present challenges in cell biology is to cultivate secretocentric thinking and thus further focusing on how we could make secretory pathways work for the benefit of human’s health
Turing Instability in a Boundary-fed System
The formation of localized structures in the chlorine dioxide-idodine-malonic
acid (CDIMA) reaction-diffusion system is investigated numerically using a
realistic model of this system. We analyze the one-dimensional patterns formed
along the gradients imposed by boundary feeds, and study their linear stability
to symmetry-breaking perturbations (Turing instability) in the plane transverse
to these gradients. We establish that an often-invoked simple local linear
analysis which neglects longitudinal diffusion is inappropriate for predicting
the linear stability of these patterns. Using a fully nonuniform analysis, we
investigate the structure of the patterns formed along the gradients and their
stability to transverse Turing pattern formation as a function of the values of
two control parameters: the malonic acid feed concentration and the size of the
reactor in the dimension along the gradients. The results from this
investigation are compared with existing experiments.Comment: 41 pages, 18 figures, to be published in Physical Review
Entanglement study of the 1D Ising model with Added Dzyaloshinsky-Moriya interaction
We have studied occurrence of quantum phase transition in the one-dimensional
spin-1/2 Ising model with added Dzyaloshinsky-Moriya (DM) interaction from bi-
partite and multi-partite entanglement point of view. Using exact numerical
solutions, we are able to study such systems up to 24 qubits. The minimum of
the entanglement ratio R \tau 2/\tau 1 < 1, as a novel estimator of
QPT, has been used to detect QPT and our calculations have shown that its
minimum took place at the critical point. We have also shown both the
global-entanglement (GE) and multipartite entanglement (ME) are maximal at the
critical point for the Ising chain with added DM interaction. Using matrix
product state approach, we have calculated the tangle and concurrence of the
model and it is able to capture and confirm our numerical experiment result.
Lack of inversion symmetry in the presence of DM interaction stimulated us to
study entanglement of three qubits in symmetric and antisymmetric way which
brings some surprising results.Comment: 18 pages, 9 figures, submitte
Pengaruh Komunikasi Terhadap Keberhasilan Proyek Pada Hubungan Kerja Antara Kontraktor dan Subkontraktor
Hubungan kerja antara perusahaan kontraktor dan subkontraktor dilaksanakan untuk mengatasi kesulitan yang muncul di lapangan agar dapat mencapai keberhasilan proyek. Untuk mencapai keberhasilan tersebut diperlukan komunikasi yang efektif antar perusahaan. Oleh karena itulah perlu dilakukan penelitian untuk menganalisis indikator pada komunikasi yang efektif dan pengaruhnya terhadap keberhasilan antar perusahaan tersebut dalam menyelesaikan pekerjaan proyek. Penelitian ini diawali dengan melakukan kajian literatur untuk mendapatkan variabel danindikator terkait komunikasi dan keberhasilan proyek. Kemudian dilakukan penyusunan kuesioner sebagai alat untuk pengumpulan data. Responden pada survey yang digunakan adalah manajer perusahaan kontraktor dan subkontraktor yang pernah atau sedang terlibat dalam hubungan kerja. Selanjutnya data yang terkumpul dilakukan analisis dengan menggunakan structural equation modelling (SEM). Hasil penelitian menunjukkan bahwa komunikasi memberikan pengaruh yang positif dan signifikan terhadap keberhasilan pekerjaan proyek antara perusahaan kontraktor dan subkontraktor. Sedangkan indikator penting pada komunikasi yang efektif adalah frekuensi komunikasi, komunikasi dua arah, kejelasan isi pesan, kejujuran berkomunikasi, dan resolusi konflik Kata kunci :komunikasi, keberhasilan proyek , hubungan kerja, structural equation modellin
A deep learning approach for intelligent cockpits: learning drivers routines
Nowadays an increasing number of vehicles are being equipped with powerful cockpit systems capable of collecting drivers’ footprints over time. The collection of this valuable data opens effective opportunities for routine prediction. With the growing ability of vehicles to collect spatial and temporal information solving the routine prediction problem becomes crucial and feasible. It is then extremely important to advance and take advantage of the capabilities of these cockpit systems. A vehicle that is capable of predicting the next destination of the driver and when the driver intends to leave to that destination can prepare the journey in advance. Previous studies tackling the next location prediction problem have made use of Traditional Markov models, Neural Networks, Dynamic models, among others. In this work, a framework based on the hierarchical density-based clustering algorithm followed by a Long Short-Term Memory (LSTM) recurrent neural network is proposed for spatial-temporal prediction of drivers’ routines. Based on real-life driving scenarios of three different users, the proposed approach achieved a test set accuracy of 96.20%, 90.23%, and 86.40% when predicting the next destination and a R2 Score of 93.69, 79.21, and 28.81 when predicting the departure time, respectively. The results indicate that the proposed architecture can be implemented on the vehicle cockpit for the assistance of the management of future trips.Programme (COMPETE 2020) and national funds, through the ADI Project Bosch & UMinho “Easy Ride: Experience is everything” , ref POCI-01-0247 FEDER-039334FCT – Fundação para a Ciência e Tecnologia within the R&D Units Project Scope: UIDB/00319/2020 and UIDB/00013/2020
High-throughput sequencing and analysis of the gill tissue transcriptome from the deep-sea hydrothermal vent mussel Bathymodiolus azoricus
© The Authors, 2010. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in BMC Genomics 11 (2010): 559, doi:10.1186/1471-2164-11-559.Bathymodiolus azoricus is a deep-sea hydrothermal vent mussel found in association with large faunal communities living in chemosynthetic environments at the bottom of the sea floor near the Azores Islands. Investigation of the exceptional physiological reactions that vent mussels have adopted in their habitat, including responses to environmental microbes, remains a difficult challenge for deep-sea biologists. In an attempt to reveal genes potentially involved in the deep-sea mussel innate immunity we carried out a high-throughput sequence analysis of freshly collected B. azoricus transcriptome using gills tissues as the primary source of immune transcripts given its strategic role in filtering the surrounding waterborne potentially infectious microorganisms. Additionally, a substantial EST data set was produced and from which a comprehensive collection of genes coding for putative proteins was organized in a dedicated database, "DeepSeaVent" the first deep-sea vent animal transcriptome database based on the 454 pyrosequencing technology. A normalized cDNA library from gills tissue was sequenced in a full 454 GS-FLX run, producing 778,996 sequencing reads. Assembly of the high quality reads resulted in 75,407 contigs of which 3,071 were singletons. A total of 39,425 transcripts were conceptually translated into amino-sequences of which 22,023 matched known proteins in the NCBI non-redundant protein database, 15,839 revealed conserved protein domains through InterPro functional classification and 9,584 were assigned with Gene Ontology terms. Queries conducted within the database enabled the identification of genes putatively involved in immune and inflammatory reactions which had not been previously evidenced in the vent mussel. Their physical counterpart was confirmed by semi-quantitative quantitative Reverse-Transcription-Polymerase Chain Reactions (RT-PCR) and their RNA transcription level by quantitative PCR (qPCR) experiments. We have established the first tissue transcriptional analysis of a deep-sea hydrothermal vent animal and generated a searchable catalog of genes that provides a direct method of identifying and retrieving vast numbers of novel coding sequences which can be applied in gene expression profiling experiments from a non-conventional model organism. This provides the most comprehensive sequence resource for identifying novel genes currently available for a deep-sea vent organism, in particular, genes putatively involved in immune and inflammatory reactions in vent mussels.
The characterization of the B. azoricus transcriptome will facilitate research into biological processes underlying physiological adaptations to hydrothermal vent environments and will provide a basis for expanding our understanding of genes putatively involved in adaptations processes during post-capture long term acclimatization experiments, at "sea-level" conditions, using B. azoricus as a model organism.We acknowledge the Portuguese Foundation for Science and Technology,
FCT-Lisbon and the Regional Azorean Directorate for Science and
Technology, DRCT-Azores, for pluri-annual and programmatic PIDDAC and
FEDER funding to IMAR/DOP Research Unit #531 and the Associated
Laboratory #9 (ISR-Lisboa); the Luso-American Foundation FLAD (Project L-V-
173/2006); the Biotechnology and Biomedicine Institute of the Azores (IBBA),
project M.2.1.2/I/029/2008-BIODEEPSEA and the project n° FCOMP-01-0124-
FEDER-007376 (ref: FCT PTDC/MAR/65991/2006-IMUNOVENT; coordinated by
RB) under the auspices of the COMPETE program
Characterization of oral yeasts isolated from healthy individuals attended in different Colombian dental clinics
The aim of this study was to identify the most frequent yeasts in the oral cavity of adult individuals without immune disorders and to associate the presence of these oral yeasts with different characteristics of each individual. Oral rinse samples were obtained from 96 healthy adults and cultured in Sabouraud dextrose agar media and CHROMagar. Yeasts were identified by sequencing the D1/D2 region of the 28S rRNA gene. Probable association among the socio-demographic characteristics, body mass index, family and personal medical history, oral hygiene, tobacco and/or alcohol consumption habits and presence of oral fungi was analyzed. Contingency tables and logistic regression were employed to evaluate possible relationships between the presence of oral fungi and mixed colonization with these variables. 57.3% of the healthy individuals had oral yeasts and 21.8% had mixed colonization. The most prevalent yeasts were Candida albicans (52%), C. parapsilosis (17.9%), and C. dubliniensis (7.57%). Yeasts with most frequently mixed colonization were C. albicans and C. parapsilosis. No relationships were found among the variables analyzed. However, the presence of mixed colonization was related to the presence of dental prostheses (P less than 0.006), dental apparatuses (P=0.016) and O'Leary index (P=0.012). This is the first study that characterized oral yeasts in Colombian healthy individuals, determined the most prevalent oral yeasts C. albicans, C. parapsilosis and C. dublinensis and an association of mixed colonization with the use of dental prostheses and aparatology and poor hygiene. © 2019 by the Journal of Biomedical Research
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