Genome wide linkage scan for loci of musical aptitude in Finnish families: Evidence for a major locus at 4q22

ABSTRACT Background: Music perception and performance are comprehensive human cognitive functions and thus provide an excellent model system for studying human behaviour and brain function. However, the molecules involved in mediating music perception and performance are so far uncharacterized

Plant patch hydrodynamics in streams : Mean flow, turbulence, and drag forces

Peer reviewedPreprin

Four novel mutations in the OFD1 (Cxorf5) gene in Finnish patients with oral-facial-digital syndrome 1

Peer reviewe

Long-term Swift and Mets\"ahovi monitoring of SDSS J164100.10+345452.7 reveals multi-wavelength correlated variability

We report on the first multi-wavelength Swift monitoring campaign performed on SDSS J164100.10+345452.7, a nearby narrow-line Seyfert 1 galaxy formerly known as radio quiet which was recently detected both in the radio (at 37 GHz) and in the $\gamma$-rays, which hints at the presence of a relativistic jet. During our 20-month Swift campaign, while pursuing the primary goal of assessing the baseline optical/UV and X-ray properties of J1641, we caught two radio flaring episodes, one each year. Our strictly simultaneous multi-wavelength data closely match the radio flare and allow us to unambiguously link the jetted radio emission of J1641. Indeed, for the X-ray spectra preceding and following the radio flare a simple absorbed power-law model is not an adequate description, and an extra absorption component is required. The average spectrum of J1641 can be best described by an absorbed power law model with a photon index $\Gamma=1.93\pm0.12$, modified by a partially covering neutral absorber with a covering fraction $f=0.91_{-0.03}^{+0.02}$. On the contrary, the X-ray spectrum closest to the radio flare does not require such extra absorber and is much harder ($\Gamma_{\rm flare} \sim 0.7\pm0.4$), thus implying the emergence of a further, harder spectral component. We interpret this as the jet emission emerging from a gap in the absorber. The fractional variability we derive in the optical/UV and X-ray bands are found to be lower than the typical values reported in the literature, since our observations of J1641 are dominated by the source being in a low state. Under the assumption that the origin of the 37 GHz radio flare is the emergence of a jet from an obscuring screen also observed in the X-rays, the derived total jet power is $P^{\rm tot}_{\rm jet}=3.5\times10^{42}$ erg s$^{-1}$, comparable to the lowest measured in the literature. [Abridged]Comment: Accepted for publication in Astronomy and Astrophysics (13 pages, 4 figures, 8 tables

Subjective face recognition difficulties, aberrant sensibility, sleeping disturbances and aberrant eating habits in families with Asperger syndrome

BACKGROUND: The present study was undertaken in order to determine whether a set of clinical features, which are not included in the DSM-IV or ICD-10 for Asperger Syndrome (AS), are associated with AS in particular or whether they are merely a familial trait that is not related to the diagnosis. METHODS: Ten large families, a total of 138 persons, of whom 58 individuals fulfilled the diagnostic criteria for AS and another 56 did not to fulfill these criteria, were studied using a structured interview focusing on the possible presence of face recognition difficulties, aberrant sensibility and eating habits and sleeping disturbances. RESULTS: The prevalence for face recognition difficulties was 46.6% in individuals with AS compared with 10.7% in the control group. The corresponding figures for subjectively reported presence of aberrant sensibilities were 91.4% and 46.6%, for sleeping disturbances 48.3% and 23.2% and for aberrant eating habits 60.3% and 14.3%, respectively. CONCLUSION: An aberrant processing of sensory information appears to be a common feature in AS. The impact of these and other clinical features that are not incorporated in the ICD-10 and DSM-IV on our understanding of AS may hitherto have been underestimated. These associated clinical traits may well be reflected by the behavioural characteristics of these individuals