6,257 research outputs found
Emergent Antiferromagnetism in D-wave Superconductor with Strong Paramagnetic Pair-Breaking
It is theoretically shown that, in the four-fold symmetric d-wave
superconducting phase, a paramagnetic pair-breaking (PPB) enhanced sufficiently
by increasing the applied magnetic field induces not only the
Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) superconducting state but also an
incommensurate antiferromagnetic (AFM) order with Q-vector parallel to a gap
node. This AFM ordering tends to occur only below H_{c2} at low temperatures,
i.e., in the presence of a nonvanishing superconducting energy gap
rather than in the normal phase. Through a detailed study on the resulting AFM
order and its interplay with the FFLO spatial modulation of , it is
argued that the strange high field and low temperature (HFLT) superconducting
phase of CeCoIn_5 is a coexisting phase of the FFLO and incommensurate AFM
orders, and that this PPB mechanism of an AFM ordering is also the origin of
the AFM quantum critical fluctuation which has occurred close to H_{c2}(0) in
several unconventional superconductors including CeCoIn_5.Comment: 22 pages, 12 figures.2 references and related comnments are
added.Accepted for publication in Phys. Rev.
Making sense of internal logic Theory and a case study
Motivated by the interf aciology proposed by Otto Rossler, we have attempted to construct a framework of internal logic of the mind and brain. We propose a functional equation as an abstract form representing mental processes. We consider a method by which such inÂternal logic can be interpreted and understood by an (external) observer. For this purpose, we propose a theory for cognitive experiments. Applying this theory to simple deductive inference processes exhibited by animal subjects in an experimental setting, with the asÂsumption that syllogism is expressed as a composite mapping corresponding to the product operation of two implications A-t Band B -t C, an interpretation of the neural activity associated with the behavior in these experiments is obtained. This theory is consistent with the internal description hypothesized by Rob Rosen
New Supporting Evidence for the Overdensity of Galaxies around the Radio-Loud Quasar SDSS J0836+0054 at z =5.8
Recently, Zheng et al. (2005) found evidence for an overdensity of galaxies
around a radio-loud quasar, SDSS J0836+0054, at z=5.8 (a five arcmin
region). We have examined our deep optical imaging data (B, V, r', i', z', and
NB816) taken with the Suprime-Cam on the Subaru Telescope. The NB816
narrow-band filter (lambda_c = 815 nm and nm) is suitable
for searching for Ly emitters at . We have found a new
strong Ly emitter at close to object B identified by
Zheng et al. Further, the non detection of the nine objects selected by Zheng
et al. (2005) in our B, V, and r' images provides supporting evidence that they
are high-z objects.Comment: 5 pages, 1 figure, accepted for PAS
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Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination.
The lethality of the aggressive brain tumor glioblastoma multiforme (GBM) results in part from its strong propensity to invade surrounding normal brain tissue. Although oncogenic drivers such as epidermal growth factor receptor activation and Phosphatase and Tensin homolog inactivation are thought to promote the motility and invasiveness of GBM cells via phosphatidylinostitol 3-kinase activation, other unexplored mechanisms may also contribute to malignancy. Here we demonstrate that several components of the planar cell polarity (PCP) arm of non-canonical Wnt signaling including VANGL1, VANGL2 and FZD7 are transcriptionally upregulated in glioma and correlate with poorer patient outcome. Knockdown of the core PCP pathway component VANGL1 suppresses the motility of GBM cell lines, pointing to an important mechanistic role for this pathway in glioblastoma malignancy. We further observe that restoration of Nrdp1, a RING finger type E3 ubiquitin ligase whose suppression in GBM also correlates with poor prognosis, reduces GBM cell migration and invasiveness by suppressing PCP signaling. Our observations indicate that Nrdp1 physically interacts with the Vangl1 and Vangl2 proteins to mediate the K63-linked polyubiquitination of the Dishevelled, Egl-10 and Pleckstrin (DEP) domain of the Wnt pathway protein Dishevelled (Dvl). Ubiquitination hinders Dvl binding to phosphatidic acid, an interaction necessary for efficient Dvl recruitment to the plasma membrane upon Wnt stimulation of Fzd receptor and for the propagation of downstream signals. We conclude that the PCP pathway contributes significantly to the motility and hence the invasiveness of GBM cells, and that Nrdp1 acts as a negative regulator of PCP signaling by inhibiting Dvl through a novel polyubiquitination mechanism. We propose that the upregulation of core PCP components, together with the loss of the key negative regulator Nrdp1, act coordinately to promote GBM invasiveness and malignancy
Strong Emission-Line Galaxies at Low Redshift in the Field around the Quasar SDSSp J104433.04-012502.2
We discuss observational properties of strong emission-line galaxies at low
redshift found by our deep imaging survey for high-redshift Ly alpha emitters.
In our surveys, we used the narrowband filter, NB816 (lambda_center=8150A with
FWHM = 120A), and the intermediate-band filter, IA827 (lambda_center = 8270A
with FWHM = 340A). In this survey, 62 NB816-excess (> 0.9 mag) and 21
IA827-excess (> 0.8 mag) objects were found. Among them, we found 20
NB816-excess and 4 IA827-excess Ly alpha emitter candidates. Therefore, it
turns out that 42 NB816-excess and 17 IA827-excess objects are strong
emission-line objects at lower redshift. Since 4 objects in the two low-z
samples are common, the total number of strong low-z emitters is 55. Applying
our photometric redshift technique, we identify 7 H alpha emitters at z~0.24,
20 H beta-[OIII] ones at z~0.65, and 11 [OII] ones at z~1.19. However, we
cannot determine reliable photometric redshifts of the remaining 17 emitters.
The distributions of their rest frame equivalent widths are consistently
understood with recent studies of galaxy evolution from z~1 to z~0.Comment: 28 pages, 8 figures, PASJ, Vol. 58, No. 1, in pres
Top-down estimate of a large source of atmospheric carbon monoxide associated with fuel combustion in Asia
We simulate the oceanic and atmospheric distribution of methyl iodide (CH3I) with a global 3-D model driven by assimilated meteorological observations from the Goddard Earth Observing System of the NASA Data Assimilation Office and coupled to an oceanic mixed layer model. A global compilation of atmospheric and oceanic observations is used to constrain and evaluate the simulation. Seawater CH3I(aq) in the model is produced photochemically from dissolved organic carbon, and is removed by reaction with Clâ and emission to the atmosphere. The net oceanic emission to the atmosphere is 214 Gg yrâ1. Small terrestrial emissions from rice paddies, wetlands, and biomass burning are also included in the model. The model captures 40% of the variance in the observed seawater CH3I(aq) concentrations. Simulated concentrations at midlatitudes in summer are too high, perhaps because of a missing biological sink of CH3I(aq). We define a marine convection index (MCI) as the ratio of upper tropospheric (8â12 km) to lower tropospheric (0â2.5 km) CH3I concentrations averaged over coherent oceanic regions. The MCI in the observations ranges from 0.11 over strongly subsiding regions (southeastern subtropical Pacific) to 0.40 over strongly upwelling regions (western equatorial Pacific). The model reproduces the observed MCI with no significant global bias (offset of only +11%) but accounts for only 15% of its spatial and seasonal variance. The MCI can be used to test marine convection in global models, complementing the use of radon-222 as a test of continental convection.Engineering and Applied Science
Nearly degenerate neutrinos, Supersymmetry and radiative corrections
If neutrinos are to play a relevant cosmological role, they must be
essentially degenerate with a mass matrix of the bimaximal mixing type. We
study this scenario in the MSSM framework, finding that if neutrino masses are
produced by a see-saw mechanism, the radiative corrections give rise to mass
splittings and mixing angles that can accommodate the atmospheric and the
(large angle MSW) solar neutrino oscillations. This provides a natural origin
for the hierarchy. On the other hand,
the vacuum oscillation solution to the solar neutrino problem is always
excluded. We discuss also in the SUSY scenario other possible effects of
radiative corrections involving the new neutrino Yukawa couplings, including
implications for triviality limits on the Majorana mass, the infrared fixed
point value of the top Yukawa coupling, and gauge coupling and bottom-tau
unification.Comment: 32 pages, 12 Postscript figures, uses psfig.st
Naturalness of nearly degenerate neutrinos
If neutrinos are to play a relevant cosmological role, they must be
essentially degenerate. We study whether radiative corrections can or cannot be
responsible for the small mass splittings, in agreement with all the available
experimental data. We perform an exhaustive exploration of the bimaximal mixing
scenario, finding that (i) the vacuum oscillations solution to the solar
neutrino problem is always excluded; (ii) if the mass matrix is produced by a
see-saw mechanism, there are large regions of the parameter space consistent
with the large angle MSW solution, providing a natural origin for the hierarchy; (iii) the bimaximal structure becomes
then stable under radiative corrections. We also provide analytical expressions
for the mass splittings and mixing angles and present a particularly simple
see-saw ansatz consistent with all observations.Comment: 25 pages, LaTeX, 6 ps figures, psfig.sty. Typos, references and minor
details corrected. Additional condition for the MSW mechanism incorporated.
New viable textures adde
Molecular and functional characterization of an evolutionarily conserved CREB-binding protein in the Lymnaea CNS
In eukaryotes, CREB-binding protein (CBP), a coactivator of CREB, functions both as a platform for recruiting other components of the transcriptional machinery and as a histone acetyltransferase (HAT) that alters chromatin structure. We previously showed that the transcriptional activity of cAMP-responsive element binding protein (CREB) plays a crucial role in neuronal plasticity in the pond snail Lymnaea stagnalis. However, there is no information on the molecular structure and HAT activity of CBP in the Lymnaea central nervous system (CNS), hindering an investigation of its postulated role in long-term memory (LTM). Here, we characterize the Lymnaea CBP (LymCBP) gene and identify a conserved domain of LymCBP as a functional HAT. Like CBPs of other species, LymCBP possesses functional domains, such as the KIX domain, which is essential for interaction with CREB and was shown to regulate LTM. In-situ hybridization showed that the staining patterns of LymCBP mRNA in CNS are very similar to those of Lymnaea CREB1. A particularly strong LymCBP mRNA signal was observed in the cerebral giant cell (CGC), an identified extrinsic modulatory interneuron of the feeding circuit, the key to both appetitive and aversive LTM for taste. Biochemical experiments using the recombinant protein of the LymCBP HAT domain showed that its enzymatic activity was blocked by classical HAT inhibitors. Preincubation of the CNS with such inhibitors blocked cAMP-induced synaptic facilitation between the CGC and an identified follower motoneuron of the feeding system. Taken together, our findings suggest a role for the HAT activity of LymCBP in synaptic plasticity in the feeding circuitry
Data production models for the CDF experiment
The data production for the CDF experiment is conducted on a large Linux PC
farm designed to meet the needs of data collection at a maximum rate of 40
MByte/sec. We present two data production models that exploits advances in
computing and communication technology. The first production farm is a
centralized system that has achieved a stable data processing rate of
approximately 2 TByte per day. The recently upgraded farm is migrated to the
SAM (Sequential Access to data via Metadata) data handling system. The software
and hardware of the CDF production farms has been successful in providing large
computing and data throughput capacity to the experiment.Comment: 8 pages, 9 figures; presented at HPC Asia2005, Beijing, China, Nov 30
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