758 research outputs found

    REGULATION OF THE CORPORATE SOCIAL RESPONSIBILITY CONCEPT IN THE COMPANY LIMITED IN INDONESIA LEGAL PRODUCTS

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    Corporate Social Responsibility (hereinafter written CSR) must be legally enforced by a Limited Liability Company that runs business activities in the field and/or related to natural resources in Indonesia. This provision comes into force since the promulgation of Law No. 40 of 2007 concerning Limited Liability Companies, State Gazette of the Republic of Indonesia of 2007 No. 106, Additional State Gazette of the Republic of Indonesia No. 4756 (hereinafter the Limited Liability Company Law). Taking into the problem, this study aims to explore more deeply about the urgency of regulating the concept of CSR from what was initially voluntary and then becoming a legal or mandatory obligation after the enactment of the Limited Liability Company Law. The type of research used in this study is a type of normative legal research, using the type of legislation approach, approach to Legal Concept Analysis and Historical approaches. Based on the result of the study, it can be concluded that the sustainability of the company will be guaranteed if the corporation participates in the interests of stakeholders and the environment in which the Limited Liability Company conducts its activities becomes one of the urgency of regulating the concept of CSR in Indonesian legal products. The basic factors that make the implementation of CSR activities in Indonesia have not run optimally are that there are still weaknesses in the regulation on the regulation of CSR concepts in Indonesia which include restrictions on companies

    The variability of the East Sakhalin Current induced by winds over the continental shelf and slope

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    Long-term current measurements of the East Sakhalin Current (ESC) in the Sea of Okhotsk are analyzed using the technique of empirical orthogonal functions (EOFs) in the frequency domain. The first and second EOFs at subtidal frequencies represent motions over the continental shelf and slope, respectively, corresponding to the variability of the two cores of the intense ESC. The first EOF can be explained by the first-mode coastal trapped wave (CTW). The structure of the second EOF is similar to that of the second-mode CTW to the first approximation. According to the distribution of the cross-spectra between EOFs and the wind stress over the whole area of the Sea of Okhotsk, the first EOF is correlated with the alongshore component of the wind stress over the northern and western shelves. The distribution of the phase of the wind stress, which is correlated with the first EOF, indicates that a resonance between the CTW and wind stress drives the motion represented by the first EOF at lower frequencies. At higher frequencies the phase of the wind stress correlated with the first EOF is almost uniform in space, being consistent with the greater speed of phase propagation of the EOF compared with that for the free CTW at these frequencies. The second EOF is correlated with the wind stress curl in the central part of the Sea of Okhotsk. The motion by the second EOF is confined over the slope at lower frequencies and becomes large over the shelf at higher frequencies. This change in the structure of the second EOF is consistent with the results of the numerical experiment of the flow induced by the offshore forcing by Chapman and Brink (1987). The phase of the wind stress curl which is correlated with the second EOF changes clearly in space at some frequencies, suggesting that the motion represented by the second EOF propagates along the isobath with the coast to the right. The wind stress curl contains the wavenumber resonant with the lowest two or three modes of CTWs

    Microfluidic encapsulation method to produce stable liposomes containing iohexol

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    Since the discovery of X-rays in the late 1890s, several medical imaging techniques have been developed, such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and Ultrasound Imaging, which are used daily to diagnose, monitor, or treat medical conditions. Some of these techniques include the use of contrast agents to enhance the contrast images, therefore, toxic effects must be considered. Among these, Contrast-Induced Nephropathy (CIN) is an acute renal failure resulting from the administration of iodinated contrast media (CM). To date, there is no definitive treatment for CIN and several prevention approaches have been evaluated. Nanoparticles (NPs) represent a promising strategy for treatment and prevention of CIN, due to their ability to deliver CM during diagnosis imaging. In this study, iohexol-containing liposomes were produced using microfluidic technique for first time. Several phosphocholine lipids (e.g. DMPC, DOPC, DPPC and DSPC) with cholesterol (2:1 ratio) were investigated and DLS, FTIR and in vitro release studies at 37 °C were performed, with stability studies conducted on the best formulation. The microfluidic method allowed to obtain a high encapsulation efficiency (over 70%), and release profiles showed an iohexol release around or less than 0.12 mg/ml after 2 h for the majority of the formulations, which is not toxic to the kidney cells

    Taste and Smell: A Unifying Chemosensory Theory

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    Since antiquity, the sense of smell (olfaction) is considered as a distance sense, just like sight and hear- ing. Conversely, the sense of taste (gustation) is thought to operate by direct contact, similarly to touch. With the progress of natural sciences, information at molecular, anatomical, and neurobiological levels has also contributed to the taste-smell dichotomy, but much evidence inconsistent with a sharp differenti- ation of these two senses has emerged, especially when considering species other than humans. In spite of this, conflicting information has been interpreted so that it could conform to the traditional differentia- tion. As a result, a confirmation bias is currently affecting scientific research on chemosensory systems and is also hindering the development of a satisfactory narrative of the evolution of chemical communi- cation across taxa. From this perspective, the chemosensory dichotomy loses its validity and usefulness. We thus propose the unification of all chemosensory modalities into a single sense, moving toward a synthetic, complex, and interconnected perspective on the gradual processes by which a vast variety of chemicals have become signals that are crucially important to communication among and within cells, organs, and or- ganisms in a wide variety of environmental conditions

    Taste and Smell: A Unifying Chemosensory Theory

    Get PDF
    Since antiquity, the sense of smell (olfaction) is considered as a distance sense, just like sight and hearing. Conversely, the sense of taste (gustation) is thought to operate by direct contact, similarly to touch. With the progress of natural sciences, information at molecular, anatomical, and neurobiological levels has also contributed to the taste-smell dichotomy, but much evidence inconsistent with a sharp differentiation of these two senses has emerged, especially when considering species other than humans. In spite of this, conflicting information has been interpreted so that it could conform to the traditional differentiation. As a result, a confirmation bias is currently affecting scientific research on chemosensory systems and is also hindering the development of a satisfactory narrative of the evolution of chemical communication across taxa. From this perspective, the chemosensory dichotomy loses its validity and usefulness. We thus propose the unification of all chemosensory modalities into a single sense, moving toward a synthetic, complex, and interconnected perspective on the gradual processes by which a vast variety of chemicals have become signals that are crucially important to communication among and within cells, organs, and organisms in a wide variety of environmental condition

    Measurement of event shapes in deep inelastic scattering at HERA

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    Inclusive event-shape variables have been measured in the current region of the Breit frame for neutral current deep inelastic ep scattering using an integrated luminosity of 45.0 pb^-1 collected with the ZEUS detector at HERA. The variables studied included thrust, jet broadening and invariant jet mass. The kinematic range covered was 10 < Q^2 < 20,480 GeV^2 and 6.10^-4 < x < 0.6, where Q^2 is the virtuality of the exchanged boson and x is the Bjorken variable. The Q dependence of the shape variables has been used in conjunction with NLO perturbative calculations and the Dokshitzer-Webber non-perturbative corrections (`power corrections') to investigate the validity of this approach.Comment: 7+25 pages, 6 figure

    An NLO QCD analysis of inclusive cross-section and jet-production data from the ZEUS experiment

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    The ZEUS inclusive differential cross-section data from HERA, for charged and neutral current processes taken with e+ and e- beams, together with differential cross-section data on inclusive jet production in e+ p scattering and dijet production in \gamma p scattering, have been used in a new NLO QCD analysis to extract the parton distribution functions of the proton. The input of jet data constrains the gluon and allows an accurate extraction of \alpha_s(M_Z) at NLO; \alpha_s(M_Z) = 0.1183 \pm 0.0028(exp.) \pm 0.0008(model) An additional uncertainty from the choice of scales is estimated as \pm 0.005. This is the first extraction of \alpha_s(M_Z) from HERA data alone.Comment: 37 pages, 14 figures, to be submitted to EPJC. PDFs available at http://durpdg.dur.ac.uk/hepdata in LHAPDFv

    Inclusive jet cross sections and dijet correlations in D±D^{*\pm} photoproduction at HERA

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    Inclusive jet cross sections in photoproduction for events containing a DD^* meson have been measured with the ZEUS detector at HERA using an integrated luminosity of 78.6pb178.6 {\rm pb}^{-1}. The events were required to have a virtuality of the incoming photon, Q2Q^2, of less than 1 GeV2^2, and a photon-proton centre-of-mass energy in the range 130<Wγp<280GeV130<W_{\gamma p}<280 {\rm GeV}. The measurements are compared with next-to-leading-order (NLO) QCD calculations. Good agreement is found with the NLO calculations over most of the measured kinematic region. Requiring a second jet in the event allowed a more detailed comparison with QCD calculations. The measured dijet cross sections are also compared to Monte Carlo (MC) models which incorporate leading-order matrix elements followed by parton showers and hadronisation. The NLO QCD predictions are in general agreement with the data although differences have been isolated to regions where contributions from higher orders are expected to be significant. The MC models give a better description than the NLO predictions of the shape of the measured cross sections.Comment: 43 pages, 12 figures, charm jets ZEU
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