16 research outputs found
Quantification of hemorphin-7 peptides by enzyme linked immunosorbent assay with secondary antibody
International audienc
Heparanase targeted for regulation of breast tumoral angiogenesis using structural analogues of heparan sulfate
International audienc
A003 ProtĂ©olyse dans le thombus de lâanĂ©vrisme de lâaorte abdominale : exemple dâun fragment dâhĂ©moglobine
Elaboration dâun modĂšle basĂ© sur des cellules endothĂ©liales microvasculaires pour Ă©tudier lâimpact de lâhĂ©paranase dans lâangiogenĂšse tumorale
International audienc
Antiproliferative activity of fish protein hydrolysates on human breast cancer cell lines
International audienceAntiproliferative activity of 18 fish protein hydrolysates was measured on 2 human breast cancer cell lines grown in vitro. Three blue whiting, three cod, three plaice and one salmon hydrolysates were identified as significant growth inhibitors on the two cancer cell lines. Preliminary analysis of hydrolysates composition evidenced they contained a complex mixture of free amino acids, peptides with various sizes ranging up to 7 kDa and in a lower proportion, lipids and sodium chloride. RP-HPLC fractionation of fish hydrolysates is currently undertaken to purify anticancer peptides, lipids or other bioactive trace compounds responsible for this antiproliferative activity