Collision probabilities of migrating small bodies and dust particles with planets

Probabilities of collisions of migrating small bodies and dust particles produced by these bodies with planets were studied. Various Jupiter-family comets, Halley-type comets, long-period comets, trans-Neptunian objects, and asteroids were considered. The total probability of collisions of any considered body or particle with all planets did not exceed 0.2. The amount of water delivered from outside of Jupiter's orbit to the Earth during the formation of the giant planets could exceed the amount of water in Earth's oceans. The ratio of the mass of water delivered to a planet by Jupiter-family comets or Halley-type comets to the mass of the planet can be greater for Mars, Venus, and Mercury, than that for Earth.Comment: 7 pages (original paper consists of 4 pages, with all sub-figures on one page). Proceedings of the IAU Symposium 263 "Icy bodies in the Solar System" (Rio de Janeiro, Brazil, 3-7 August, 2009), ed. by D. Lazzaro, D. Prialnik, R. Schulz, J.A. Fernandez, submitte

IMPROVING FLOW DISTRIBUTION IN SMALL-SCALE WATER-SUPPLY SYSTEMS THROUGH THE USE OF FLOW-REDUCING DISCS AND METHODS FOR ANALYZING THE EFFECTIVENESS OF SOLAR POWERED PUMPING FOR A DRINKING WATER SUPPLY IN RURAL PANAMA

As continued global funding and coordination are allocated toward the improvement of access to safe sources of drinking water, alternative solutions may be necessary to expand implementation to remote communities. This report evaluates two technologies used in a small water distribution system in a mountainous region of Panama; solar powered pumping and flow-reducing discs. The two parts of the system function independently, but were both chosen for their ability to mitigate unique issues in the community. The design program NeatWork and flow-reducing discs were evaluated because they are tools taught to Peace Corps Volunteers in Panama. Even when ample water is available, mountainous terrains affect the pressure available throughout a water distribution system. Since the static head in the system only varies with the height of water in the tank, frictional losses from pipes and fittings must be exploited to balance out the inequalities caused by the uneven terrain. Reducing the maximum allowable flow to connections through the installation of flow-reducing discs can help to retain enough residual pressure in the main distribution lines to provide reliable service to all connections. NeatWork was calibrated to measured flow rates by changing the orifice coefficient (θ), resulting in a value of 0.68, which is 10-15% higher than typical values for manufactured flow-reducing discs. NeatWork was used to model various system configurations to determine if a single-sized flow-reducing disc could provide equitable flow rates throughout an entire system. There is a strong correlation between the optimum single-sized flow- reducing disc and the average elevation change throughout a water distribution system; the larger the elevation change across the system, the smaller the recommended uniform orifice size. Renewable energy can jump the infrastructure gap and provide basic services at a fraction of the cost and time required to install transmission lines. Methods for the assessment of solar powered pumping systems as a means for rural water supply are presented and assessed. It was determined that manufacturer provided product specifications can be used to appropriately design a solar pumping system, but care must be taken to ensure that sufficient water can be provided to the system despite variations in solar intensity

New RR Lyrae variables in binary systems

Despite their importance, very few RR Lyrae (RRL) stars have been known to reside in binary systems. We report on a search for binary RRL in the OGLE-III Galactic bulge data. Our approach consists in the search for evidence of the light-travel time effect in so-called observed minus calculated ($O-C$) diagrams. Analysis of 1952 well-observed fundamental-mode RRL in the OGLE-III data revealed an initial sample of 29 candidates. We used the recently released OGLE-IV data to extend the baselines up to 17 years, leading to a final sample of 12 firm binary candidates. We provide $O-C$ diagrams and binary parameters for this final sample, and also discuss the properties of 8 additional candidate binaries whose parameters cannot be firmly determined at present. We also estimate that $\gtrsim 4$ per cent of the RRL reside in binary systems.Comment: MNRAS Letters, in pres

Two-photon E1M1 decay of 2 3P0 states in heavy heliumlike ions

Two-photon E1M1 transition rates are evaluated for heliumlike ions with nuclear charges in the range Z = 50-94. The two-photon rates modify previously published lifetimes/transition rates of 2 3P0 states. For isotopes with nuclear spin I not equal 0, where hyperfine quenching dominates the 2 3P0 decay, two-photon contributions are significant; for example, in heliumlike 187 Os the two-photon correction is 3% of the total rate. For isotopes with I= 0, where the 2 3P0 decay is unquenched, the E1M1 corrections are even more important reaching 60% for Z=94. Therefore, to aid in the interpretation of experiments on hyperfine quenching in heliumlike ions and to provide a more complete database for unquenched transitions, a knowledge of E1M1 rates is important.Comment: 6 pages, 3 figures, 3 table

Nonrelativistic ionization energy for the helium ground state

The helium ground state nonrelativistic energy with 24 significant digits is presented. The calculations are based on variational expansion with randomly chosen exponents. This data can be used as a benchmark for other approaches for many electron and/or three-body systems.Comment: 3 pages, 0 figure

Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering

CheY, the 14-kDa response regulator protein of the Escherichia coli chemotaxis pathway, is activated by phosphorylation of Asp57. In order to probe the structural changes associated with activation, an approach which combines 19F NMR, protein engineering, and the known crystal structure of one conformer has been utilized. This first of two papers examines the effects of Mg(II) binding and phosphorylation on the conformation of CheY. The molecule was selectively labeled at its six phenylalanine positions by incorporation of 4-fluorophenylalanine, which yielded no significant effect on activity. One of these 19F probe positions monitored the vicinity of Lys109, which forms a salt bridge to Asp57 in the apoprotein and has been proposed to act as a structural "switch" in activation. 19F NMR chemical shift studies of the labeled protein revealed that the binding of the cofactor Mg(II) triggered local structural changes in the activation site, but did not perturb the probe of the Lys109 region. The structural changes associated with phosphorylation were then examined, utilizing acetyl phosphate to chemically generate phsopho-CheY during NMR acquisition. Phosphorylation triggered a long-range conformational change extending from the activation site to a cluster of 4 phenylalanine residues at the other end of the molecule. However, phosphorylation did not perturb the probe of Lys109. The observed phosphorylated conformer is proposed to be the first step in the activation of CheY; later steps appear to perturb Lys109, as evidenced in the following paper. Together these results may give insight into the activation of other prokaryotic response regulators

Reduced brain activity during a working memory task in middle-aged apolipoprotein E +4 carriers with overweight/obesity

Objective: The apolipoprotein E +4 (APOE +4) allele and midlife obesity are independent risk factors for Alzheimer’s disease (AD). Both of these risk factors are also associated with differences in brain activation, as measured by blood oxygenation level-dependent (BOLD) responses, in the absence of detectable cognitive deficits. Although the presence of these risk factors may influence brain activity during working memory tasks, no study to date has examined whether the presence of the +4 allele explains variation in working memory brain activity while matching for levels of overweight/obesity. The primary aim of this study was to determine whether the presence of the +4 allele is associated with differences in task-functional magnetic resonance imaging (fMRI) brain activation in adults with overweight/obesity. We predicted that +4 carriers would have greater brain activation in regions that support working memory. Methods: This ancillary study included 48 (n = 24 APOE +4 carriers; n = 24 APOE +4 non-carriers), sedentary middle-aged adults (Mean age = 44.63 8.36 years) with overweight/obesity (Mean BMI = 32.43 4.12 kg/m2) who were matched on demographic characteristics. Participants were a subsample enrolled in 12-month randomized clinical trial examining the impact of energy-restricted diet and exercise on cardiovascular health outcomes. Participants completed a n-back working memory task with fMRI, which were completed within one month of the start of the intervention. Participants also underwent pseudo-continuous arterial spin labeling scans, a MRI measure of cerebral blood flow (CBF). Results: Compared to non-+4 carriers with overweight/obesity, +4 carriers with overweight/obesity had lower fMRI brain activity in the middle frontal gyrus, pre and post central gyrus, supramarginal gyrus, superior temporal gyrus, lateral occipital cortex, and angular gyrus (z range = 2.52–3.56) during the n-back working memory task. Differences persisted even when controlling for CBF in these brain regions. Conclusion: These results indicate that presence of the APOE +4 allele in middle-aged adults with overweight/obesity is related to altered brain activity during a working memory paradigm, which may confer risk for accelerated neurocognitive decline in late adulthood. Future research is needed to clarify the clinical implications of these findings in the context of risk for AD.United States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA University of Pittsburgh Clinical and Translational Science Institute (CTSI) 3R01AG060741-03S1 R01 DK095172 R01-HL103646 UL1 TR00185

Relativistic, QED, and nuclear mass effects in the magnetic shielding of 3^3He

The magnetic shielding $\sigma$ of $^3$He is studied. The complete relativistic corrections of order $O(\alpha^2)$, leading QED corrections of order $O(\alpha^3 \ln\alpha)$, and finite nuclear mass effects of order $O(m/m_{\rm N})$ are calculated with high numerical precision. The resulting theoretical predictions for $\sigma = 59.967~43(10)\cdot 10^{-6}$ are the most accurate to date among all elements and support the use of $^3$He as a NMR standard.Comment: 10 pages, corrected minor errors in Eqs.(6,7