Three Years Survival Rate of Epithelial Ovarian Cancer Patients in Dr. Kariadi Hospital, Semarang, Central Java

Objectives: to determine the association between prognostic factors of ovarian cancer with a 3-years survival rate of epithelial ovarian cancer patients.Material and Method: Retrospective cohort study was conducted in 90 patients (during 2012) at Dr.Kariadi General Hospital. Kaplan meier, Log rank and Cox regression were used to analyse survival rate and prognostic factors that influence the disease.Result: Overall 3-years survival rate of epithelial ovarian cancer patients were 58.5% (Kaplan meier). Three-years survival rates were 89.3%, 44,4%, and 35.1% for patients in stage I, stage II, and stage III, respectively, and no patient survive up to 3 years in stage IV. Prognostic factors that associated with 3-years survival rate were stage of the disease, ascites, residual tumor, and type of histopathology {p<0,001; p=0,001; p=0,004; p=0,041, respectively (Log rank test)}, whereas age and size of tumor were not associated. After using multivariate analysis (Cox regression) only stage of the disease was associated with 3-years survival rate of epithelial ovarian cancer patients.Conclusion: There were an association between stage of the disease, ascites, residual tumor, type of histopathology, and 3-years survival rate of epithelial ovarian cancer patients. Stage of the disease was a prognostic factor that most influence 3-years survival rate of epithelial ovarian cancer patiens in this study

Pengaruh Kesalahan Penulisan Komparisi Terhadap Suatu Akta Autentik Notaris Ditinjau Dari Hukum Pembuktian

Development of legal relations in society, the need for legal services that can protect the interests of the community in the form of evidence in the Deed of authentic increasing, because in the Deed of authentic contained all the elements of evidence, determine the rights and obligations, ensure legal certainty, and is expected to prevent a dispute, PPAT as the Notary Deed authentic authority to make on the basis of the desire or the will of the parties. Under the Civil Code, a deed so authentic it must be made according to the form and manner determined by the Act. Komparisi is one of the most important part in making authentic deed which contains Identity, skills and authority to act, and the position of the parties, as stipulated in Law No. 2 of 2014. Writing komparisi requires understanding, prudence and thoroughness, as komparisi decisive the validity of a deed. This is true, but in the world practice there are errors that must be faced Notary, one of which is a typing error in komparisi. Komparisi writing errors may occur due to lack precisely apply the provisions stipulated in the Act, and from the evidence by the parties. Komparisi writing error can be attempted to be fixed for mandatory repairs to be done, because in principle what is contained in the Deed of authentic must be true. Based on the authors conducted a study to raise the issue as to whether writing errors komparisi can affect the value of the deed strength in terms of the basic rules of evidence, and what form that effort should be made if an error occurs writing komparisi. This research to be used by normative and being followed by the law and the case through systimatic aggreement. Based on the results of this research is that errors can be expressed writing komparisi wrong if based on the evidence. Error writing komparisi Notary deed that is not attempted repair may affect the deed and the parties in the deed. In terms of value the power of the deed, if repaired correctly then the value of the strength of evidence is perfect, and if repaired but one of the value of the strength of evidence is not perfect, pursuant to section 41 UUJN and 1869 of the Civil Code. Efforts to do if an error occurs writing komparisi is to make improvements through Renvooi under article 48 paragraph 2 UUJN or through Erratum under article 51 paragraph 2 and 3 UUJN. Komparisi writing error correction must be made according to the procedure determined by the events of the Act, so that the value of the power of the deed can be used as evidence that a strong and binding, and not degraded

Neurodermatitis Sirkumskripta Pada Wanita Dengan Hipertensi Grade I Terkontrol

Latar Belakang. Neurodermatitis sirkumskripta atau juga dikenal dengan liken simpleks kronis adalah penyakit peradangan kronis pada kulit, gatal, sirkumskripta, dan khas ditandai dengan likenifikasi. Likenifikasi timbul sebagai respon dari kulit akibat gosokan dan garukan yang berulang-ulang dalam waktu yang cukup lama, sehingga garis kulit tampak lebih menonjol menyerupai kulit batang kayu. Kasus. Ny. S, 50 tahun, datang dengan keluhan kulit terasa menebal dan gatal pada kedua pergelangan kaki sejak 2 bulan yang lalu. Awalnya keluhan timbul berupa bercak merah berukuran sebesar uang logam. Bercak tersebut disertai rasa gatal sehingga pasien seringkali menggaruk dengan keras bagian yang gatal tersebut. Pasien mengaku rasa gatal bersifat hilang timbul dan biasanya muncul pada malam hari ketika sedang istirahat. Pasien memiliki riwayat hipertensi grade I sejak 1 tahun lalu dan rutin minum obat anti hipertensi setiap hari. Status dermatologis pedis dekstra et sinistra: tampak plak hiperpigmentasi berukuran plakat dengan tepi ekskoriasi dan likenifikasi serta skuama. Simpulan. Neurodermatitis sirkumskripta pada pasien tersebut dipicu oleh lingkungan dan suhu serta stress terkait dengan hipertensi yang dialami. [Medula Unila.2014;2(3):44-51

Factors Associated with Wound Healing Post Sectio Caesarea at Arifin Achmad General Hospital Riau Province in 2013

Post Sectio Caesarea wound is a wound that made an impression and is caused by cesarean when a woman can not give birth main normal. Prinsip in wound care is the control of infection because infection can inhibit wound healing, causing morbidity and mortality increase. This study aims to determine the factors associated with wound healing post sectio caesareadi Arifin Achmad Riau Province in 2013. This research is quantitative research using cross sectional study design. The location of research is Arifin Achmad Riau Province, the research was conducted in October-May 2014. The population in this study is the status of the mother\u27s Medical Record sectio caesarea in 2013 amounted to 910 people with a sample of 154 people. Systematic sampling technique is random sampling. The data used in this research is secondary data is data mothers delivered in SC, age, mother of data with infection and disease history data. Data analysis for bivariate with Chi-Square test. &nbsp;The results show for the factors associated with wound healing post sectio caesarea is variable risk age 79 (51.3%), OR = 2.91 (95% CI: 1.50 to 5.65), maternal variables 83 infections (53.9%), OR = 6.59 (95% CI: 3.24 to 13.41), and a mother who suffered variables Diabetes 80 (51.90%), OR = 3.06 ( 95% CI: 1.57 to 5.94). The conclusion of this study is that there is a relationship of age, infection and diabetes mellitus with wound healing post sectio caesarea. Expected to health professionals in order to further improve the education and information about wound care operations, and better monitor the healing of wounds with age and history of diabetes mellitus yan suffered by the patient.&nbsp

Factors Associated with Cervical Cancer Incidence Arifin Achmad Hospital in Pekanbaru Year 2008-2010

Cervical cancer is a primary Malignant tumor derived from epithelial cells of cervical squamous or cervix. The most common cause of cervical cancer is infection with HPV (Human Papilloma Virus), several factors are thought to increase the incidence of cervical cancer is sosiodemografis factors which include age, socioeconomic status, and sexual activity of factors that include age at first intercourse, partner change sex -replace, parity, lack of genital hygiene, smoking, history of venereal disease, chronic trauma to the cervix, as well as the use of hormonal contraceptives. The purpose of this study are known risk factors associated with cervical cancer incidence in Arifin Achmad Riau Province Year 2008-2010. This type of study is a case-control (case control study). The case of women with cervical cancer who were treated at the Arifin Achmad Riau Province, and control of cervical cancer Women are not treated at the Arifin Achmad Riau Province. The results of this study showed women with heavy work more at risk for developing cervical cancer 9 times compared with women who have jobs lightweight (OR 9,184), low-educated women four times more likely to suffer from cervical cancer compared with women who are highly educated (OR 3,698), female age at first intercourse less than 20 years 3 times higher risk of cervical cancer compared to women with age at first sexual intercourse (OR 2,792)and women above 20 years who had parity&gt; 3 children dibandingakn 7 times greater risk to women with a parity &lt;3 children (OR 3,396). As Conclusions, &nbsp;occupation, education, age of first sexual intercourse and parity have based on the results of multivariate analysis of independent variables that have a causal relationship with the incidence of cervical cancer is work, education, age at first sexual intercourse and parity. Independent variables that have no causal relationship with the incidence of cervical cancer is are sexual partners. And independent of confounding variables by are kejadaian incidence of cervical cancer is the use of hormonal contraception, sexually transmitted diseases and age. Advice intended for Riau provincial health office of Riau Province, Arifin Achmad Riau provinceGeneral Hospital, society community and further research.&nbsp

Pathogenicity of local isolate virus BHV-1 as the aetiological agent of Infectious Bovine Rhinotracheitis in Bali Cattle

Infectious Bovine Rhinotracheitis is a disease of cattle characterised by clinical signs of the upper respiratory tract, reproductive tract and nervous system. A study to define the pathogenicity of four BHV-1 local isolates has been conducted. Fourteen Bali cattle that were free of BHV-1 has been selected and divided into four treatment groups. Each group of three was infected with virus isolate I, II, III and IV respectively with approximately a dose of 108TCID50 /10 ml and two cattle were used as control animals. Isolate I and III were originated from semen from IBR positive bulls number G 867 and G 148 respectively whereas isolate II was collected from vaginal mucosa and isolate IV was from nasal mucosa of IBR positive cattle treated with dexamethasone. Clinical response, gross-pathological and histopathological changes were observed. Immunohistochemical staining was applied to detect the antigen in tissue section. The results show that the BHV-1 local isolates could produce IBR syndrome namely fever and changes in the respiratory and reproductive tracts even though the clinical responses seemed to be disappeared by 21 days PI. Grossly there were hyperaemic nasal and vaginal mucosa and pneumonia whereas histologically there were non suppurative rhinitis, tracheitis, pneumonia and vulvovaginitis. Immunohistochemically the antigen was detected in the nasal concha and trachea. Dexamethasone treatment at 60-64 days PI could produce less severe clinical features and the second necroppsy at 69 days PI also results in less severe pathological responses. The findings also suggest that the pathogenicity of BHV-1 local isolates were as follows: isolates I, II, IV and III.     Key Words: Pathogenicity, BHV-1, Infectious Bovine Rhinotracheitis (IBR), Bali Cattl

Pengaruh Ukuran Perusahaan, Profitabilitas dan Risiko Bisnis terhadap Struktur Modal pada Perusahaan Manufaktur di Bei

The purpose of this study is to determine the effect of Company Size, Profitability, and Business Risk on Capital Structure in Manufacturing Companies In Indonesia Stock Exchange Period 2013-2015. The population in this study are all manufacturing companies in Indonesia Stock Exchange which amounts to 150 companies. The technique of determining the sample used is purposive sampling, so the final sample is 40 manufacturing companies in Indonesia Stock Exchange. Data collection method used is non participant observation .. This study used multiple linear regression analysis techniques with the help of SPSS 22 for windows applications. Based on the results of the analysis shows that: 1) Company size has a positive and significant effect on the capital structure of the company in Indonesia Stock Exchange, 2) Profitability and Risk has a negative and insignificant effect on the capital structure at manufacturing company in Stock Exchang