Vacuolar myopathy in a dog resembling human sporadic inclusion body myositis

Sporadic inclusion body myositis (sIBM) is the most common myopathy in people over the age of 50 years. While immune-mediated inflammatory myopathies are well documented in dogs, sIBM has not been described. An 11-year-old dog with chronic and progressive neuromuscular dysfunction was evaluated for evidence of sIBM using current pathologic, immunohistochemical and electron microscopic diagnostic criteria. Vacuoles and congophilic intracellular inclusions were identified in cryostat sections of multiple muscle biopsies and immunostained with antibodies against amyloid-β peptide, amyloid-β precursor protein, and proteosome 20S of the ubiquitin–proteosome system. Cellular infiltration and increased expression of MHC Class I antigen were observed. Cytoplasmic filamentous inclusions, membranous structures, and myeloid bodies were identified ultrastructurally. These observations constitute the first evidence that both the inflammatory and degenerative features of human sIBM can occur in a non-human species

Dacryops in a red-eared slider (Chrysemys scripta elegans) : Case report.

Clinical and histologic findings of an orbital lacrimal cyst (dacryops) in a 23-year-old-female red-eared slider (Chrysemys scripta elegans) are described. Main ophthalmologic findings included unilateral exophthalmus, engorged episcleral vessels, periocular swelling superior to the globe, incomplete lid closure, and reduced ocular motility. Based on sonographic and cytologic examination of the tissue, the preliminary diagnosis of an orbital cyst was established. After surgical resection of the cystic structure, the eye remained visual but enophthalmic. Histopathologic diagnosis of the resected tissue was interstitial dacryoadenitis

Combination of imaging spectrometer data and high resolution LIDAR data by 3-D radiative transfer modeling

Coniferous forests represent canopies with a high heterogeneity in the horizontal and as well in the vertical dimension. Consequently the interaction of incident radiation is dominated by the complex 3-D canopy structure and architecture. Radiative transfer approaches based on coupled leaf and canopy radiative transfer models (RTM) still allow the simulation of the multidirectional canopy reflectance as a function of leaf optical properties, canopy structure and viewing geometry as well as the retrieval of biophysical and biochemical canopy variables. High-resolution imaging spectrometry supported by light detection and ranging (LIDAR) data and the complex 3-D radiative transfer model FLIGHT (North, 1996) are employed to assess the influence of canopy heterogeneity and structure on canopy reflection. Exhaustive ground measurements of biochemical and biophysical parameters combined with the geometry of single trees derived from LIDAR data provide the possibility of a realistic scene parameterization of a boreal forest in Switzerland