471 research outputs found
Primary Squamous Cell Carcinoma in the Testis: A Case Report
A 51-yr-old man presented with an enlarged right testis for two months. The radically resected testis showed a relatively well-circumscribed ovoid mass, nearly replacing the normal architecture with central cystic changes. Microscopically, the mass was composed of ovoid shaped tumor cells of a moderately differentiated squamous cell carcinoma (SCC). The central portion of the mass was filled with well-formed laminated keratinous materials and the remnant cavity lined by dysplastic squamous epithelium, indicated SCC may be derived from an epidermal cyst. SCC is among the most common types of neoplasm afflicting human beings, but it is rare in the testis. To our knowledge, this is the second report of the testicular squamous cell carcinoma occurring in a patient without other primary tumors, and the firstly reported case in Korea
NASA ExoPAG Study Analysis Group 11: Preparing for the WFIRST Microlensing Survey
NASA's proposed WFIRST-AFTA mission will discover thousands of exoplanets
with separations from the habitable zone out to unbound planets, using the
technique of gravitational microlensing. The Study Analysis Group 11 of the
NASA Exoplanet Program Analysis Group was convened to explore scientific
programs that can be undertaken now, and in the years leading up to WFIRST's
launch, in order to maximize the mission's scientific return and to reduce
technical and scientific risk. This report presents those findings, which
include suggested precursor Hubble Space Telescope observations, a
ground-based, NIR microlensing survey, and other programs to develop and deepen
community scientific expertise prior to the mission.Comment: 35 pages, 5 Figures. A brief overview of the findings is presented in
the Executive Summary (2 pages
Detection Probability of a Low-Mass Planet for Triple Lens Events: Implication of Properties of Binary-Lens Superposition
In view of the assumption that any planetary system is likely to be composed
of more than one planet, and the multiple planet system with a large mass
planet has more chance of detailed follow-up observations, the multiple planet
system may be an efficient way to search for sub-Jovian planets. We compare the
magnification pattern of the triple lens system with that of a best-fitted
binary system composed of a star and a Jovian mass planet, and check the
probability in detecting the low-mass secondary planet whose signature will be
superposed on that of the primary Jovian mass planet. Detection probabilities
of the low-mass planet in the triple lens system are quite similar to the
probability in detecting such a low-mass planet in a binary system with a star
and only a low-mass planet, which shows that the signature of a low-mass planet
can be effectively detected even when it is concurrent with the signature of
the more massive planet, implying that the binary superposition approximation
works over a relatively broad range of planet mass ratio and separations, and
the inaccuracies thereof do not significantly affect the detection probability
of the lower mass secondary planet. Since the signature of the Jovian mass
planet will be larger and lasts longer, thereby warranting more intensive
follow-up observations, the actual detection rate of the low-mass planet in a
triple system with a Jovian mass can be significantly higher than that in a
binary system with a low-mass planet only. We conclude that it may be
worthwhile to develop an efficient algorithm to search for `super-Earth'
planets in the paradigm of the triple lens model for high-magnification
microlensing events.Comment: 10 pages, 5 figures, accepted by MNRA
KMT-2016-BLG-1107: A New Hollywood-Planet Close/Wide Degeneracy
We show that microlensing event KMT-2016-BLG-1107 displays a new type of
degeneracy between wide-binary and close-binary Hollywood events in which a
giant-star source envelops the planetary caustic. The planetary anomaly takes
the form of a smooth, two-day "bump" far out on the falling wing of the light
curve, which can be interpreted either as the source completely enveloping a
minor-image caustic due to a close companion with mass ratio , or
partially enveloping a major-image caustic due to a wide companion with
. The best estimates of the companion masses are both in the planetary
regime ( and ) but differ by an even larger factor than the mass ratios due to
different inferred host masses. We show that the two solutions can be
distinguished by high-resolution imaging at first light on next-generation
("30m") telescopes. We provide analytic guidance to understand the conditions
under which this new type of degeneracy can appear.Comment: 23 pages, 7 figures, accepted for publication in A
KMT-2018-BLG-1990Lb: A Nearby Jovian Planet From A Low-Cadence Microlensing Field
We report the discovery and characterization of KMT-2018-BLG-1990Lb, a Jovian
planet orbiting a late M dwarf
, at a distance
(D_L=1.23_{-0.43}^{+1.06}\,\kpc), and projected at times the
snow line distance, i.e., a_{\rm snow}\equiv 2.7\,\au (M/M_\odot), This is
the second Jovian planet discovered by KMTNet in its low cadence () fields, demonstrating that this population will be well
characterized based on survey-only microlensing data.Comment: 24 pages, 7 figures, 4 table
KMT-2018-BLG-1292: A Super-Jovian Microlens Planet in the Galactic Plane
We report the discovery of KMT-2018-BLG-1292Lb, a super-Jovian planet orbiting an F or G dwarf , which lies physically within {\cal O}(10\,\pc) of the
Galactic plane. The source star is a heavily extincted luminous
giant that has the lowest Galactic latitude, , of any planetary
microlensing event. The relatively blue blended light is almost certainly
either the host or its binary companion, with the first explanation being
substantially more likely. This blend dominates the light at band and
completely dominates at and bands. Hence, the lens system can be probed
by follow-up observations immediately, i.e., long before the lens system and
the source separate due to their relative proper motion. The system is well
characterized despite the low cadence -- of
observations and short viewing windows near the end of the bulge season. This
suggests that optical microlensing planet searches can be extended to the
Galactic plane at relatively modest cost.Comment: 35 pages, 3 Tables, 8 figure
Clinical Outcomes and Prognostic Factors of Up-Front Autologous Stem Cell Transplantation in Patients with Extranodal Natural Killer/T Cell Lymphoma
AbstractLimited data exist on up-front autologous stem cell transplantation (ASCT) in extranodal natural killer/T cell lymphoma (ENKTL). Sixty-two patients (43 men and 19 women) with newly diagnosed ENKTL who underwent up-front ASCT after primary therapy were identified. Poor-risk characteristics included advanced stage (50%), high-intermediate to high-risk International Prognostic Index (25.8%), and group 3 to 4 of NK/T Cell Lymphoma Prognostic Index (NKPI, 67.7%). Pretransplant responses included complete remission in 61.3% and partial remission in 38.7% of patients, and final post-transplantation response included complete remission in 78.3%. Early progression occurred in 12.9%. At a median follow-up of 43.3 months (range, 3.7 to 114.6), 3-year progression-free survival (PFS) was 52.4% and 3-year overall survival (OS) was 60.0%. Patients with limited disease had significantly better 3-year PFS (64.5% versus 40.1%, PÂ = .017) and OS (67.6% versus 52.3%, PÂ = .048) than those with advanced disease. Multivariate analysis showed NKPI and pretransplant response were independent prognostic factors influencing survival, particularly NKPI in limited disease and pretransplant response in advanced disease. Radiotherapy was an independent factor for reduced progression and survival in patients with limited disease, but anthracycline-based chemotherapy was a poor prognostic factor for progression in patients with advanced disease. Up-front ASCT is an active treatment in ENKTL patients responding to primary therapy
OGLE-2018-BLG-0532Lb: Cold Neptune With Possible Jovian Sibling
We report the discovery of the planet OGLE-2018-BLG-0532Lb, with very obvious
signatures in the light curve that lead to an estimate of the planet-host mass
ratio . Although there are
no obvious systematic residuals to this double-lens/single-source (2L1S) fit,
we find that can be significantly improved by adding either a third
lens (3L1S, ) or second source (2L2S, ) to
the lens-source geometry. After thorough investigation, we conclude that we
cannot decisively distinguish between these two scenarios and therefore focus
on the robustly-detected planet. However, given the possible presence of a
second planet, we investigate to what degree and with what probability such
additional planets may affect seemingly single-planet light curves. Our best
estimates for the properties of the lens star and the secure planet are: a host
mass , system distance kpc and planet mass
with projected separation au.
However, there is a relatively bright (and also relatively blue) star
projected within mas of the lens, and if future high-resolution images
show that this is coincident with the lens, then it is possible that it is the
lens, in which case, the lens would be both more massive and more distant than
the best-estimated values above.Comment: 48 pages, 9 figures, 7 table
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