BPS D-branes from an Unstable D-brane in a Curved Background

We find exact tachyon kink solutions of DBI type effective action describing an unstable D5-brane with worldvolume gauge field turned on in a curved background. The background of interest is the ten-dimensional lift of the Salam-Sezgin vacuum and, in the asymptotic limit, it approaches ${\rm R}^{1,4}\times {\rm T}^2\times {\rm S}^3$. The solutions are identified as composites of lower-dimensional D-branes and fundamental strings, and, in the BPS limit, they become a D4D2F1 composite wrapped on ${\rm R}^{1,2}\times {\rm T}^2$ where ${\rm T}^2$ is inside ${\rm S}^3$. In one class of solutions we find an infinite degeneracy with respect to a constant magnetic field along the direction of NS-NS field on ${\rm S}^3$.Comment: 16 pages, 2 figures, a footnote added, typos corrected and a reference adde

BPS D-branes from an Unstable D-brane

We search for exact tachyon kink solutions of DBI type effective action describing an unstable D-brane with worldvolume gauge field turned in both the flat and a curved background. There are various kinds of solutions in the presence of electromagnetic fields in the flat space, such as periodic arrays, topological tachyon kinks, half kinks, and bounces. We identify a BPS object, D($p$-1)F1 bound state, which describes a thick brane with string flux density. The curved background of interest is the ten-dimensional lift of the Salam-Sezgin vacuum and, in the asymptotic limit, it approaches ${\rm R}^{1,4}\times {\rm T}^2\times {\rm S}^3$. The solutions in the curved background are identified as composites of lower-dimensional D-branes and fundamental strings, and, in the BPS limit, they become a D4D2F1 composite wrapped on ${\rm R}^{1,2}\times {\rm T}^2$ where ${\rm T}^2$ is inside ${\rm S}^3$.Comment: 4 pages, to appear in the proceeding of PASCOS 2005, Gyeongju, Korea, May 30-June 4, 200

Simultaneous Constructions of the Sporadic Groups Co_2 and Fi_{22}

In this article we give self-contained existence proofs for the sporadic simple groups Co_2 and Fi_{22} using the second author's algorithm [10] constructing finite simple groups from irreducible subgroups of GL_n(2). These two sporadic groups were originally discovered by J. Conway [4] and B. Fischer [7], respectively, by means of completely different and unrelated methods. In this article n=10 and the irreducible subgroups are the Mathieu group M_{22} and its automorphism group Aut(M_{22}). We construct their five non-isomorphic extensions E_i by the two 10-dimensional non-isomorphic simple modules of M_{22} and by the two 10-dimensional simple modules of A_{22} = Aut(M_{22}) over F=GF(2). In two cases we construct the centralizer H_i = C_{G_i}(z_i) of a 2-central involution z_i of E_i in any target simple group G_i. Then we prove that all the conditions of Algorithm 7.4.8 of [11] are satisfied. This allows us to construct G_3 $\cong$ Co_2 inside GL_{23}(13) and G_2 $\cong$ Fi_{22} inside GL_{78}(13). We also calculate their character tables and presentations.Comment: 94 page

Experimental Investigation of Crossing Shock Wave-Turbulent Boundary Layer-Bleed Interaction

Results of an experimental investigation of a symmetric crossing shock wave/turbulent boundary layer/bleed interaction are presented for a freestream unit Reynolds number of 1.68 x 10(exp 7)/m, a Mach number of 2.81, and deflection angles of 8 degrees. The data obtained in this study are bleed mass flow rate using a trace gas technique, qualitative information in the form of oil flow visualization, flow field Pitot pressures, and static pressure measurements using pressure sensitive paint. The main objective of this test is two-fold. First, this study is conducted to explore boundary layer control through mass flow removal near a large region of separated flow caused by the interaction of a double fin-induced shock wave and an incoming turbulent boundary layer. Also, a comprehensive data set is needed for computational fluid dynamics code validation

Real-time observations of TRIP-induced ultrahigh strain hardening in a dual-phase CrMnFeCoNi high-entropy alloy.

Strategies involving metastable phases have been the basis of the design of numerous alloys, yet research on metastable high-entropy alloys is still in its infancy. In dual-phase high-entropy alloys, the combination of local chemical environments and loading-induced crystal structure changes suggests a relationship between deformation mechanisms and chemical atomic distribution, which we examine in here in a Cantor-like Cr20Mn6Fe34Co34Ni6 alloy, comprising both face-centered cubic (fcc) and hexagonal closed packed (hcp) phases. We observe that partial dislocation activities result in stable three-dimensional stacking-fault networks. Additionally, the fraction of the stronger hcp phase progressively increases during plastic deformation by forming at the stacking-fault network boundaries in the fcc phase, serving as the major source of strain hardening. In this context, variations in local chemical composition promote a high density of Lomer-Cottrell locks, which facilitate the construction of the stacking-fault networks to provide nucleation sites for the hcp phase transformation

The Protein Kinase C Inhibitor Aeb071 (Sotrastaurin) Modulates Migration and Superoxide Anion Production by Human Neutrophils In Vitro

We examined the effect of the protein kinase C-selective inhibitor AEB071 (sotrastaurin) on neutrophil functions in vitro. Pre-incubation with AEB071 at concentrations similar to those reached during in vivo therapy significantly reduced cell capacity to migrate toward three different chemo-attractants and to produce superoxide anions (O2) in response to phorbol myristate acetate (PMA) or to iV-formyl-methionyl-leucyl-phenylalanine (fMLP). AEB071 also significantly inhibited the O−2 "overproduction induced by fMLP in neutrophils primed with tumor necrosis factor alpha (TNF-α) or granulocyte/macrophage-colony stimulating factor (GM-CSF). This inhibition was not linked to fMLP-receptor down-regulation since the drug had no effect on either fMLP-receptors or fMLP-induced CD11b membrane expression. When the activity of AEB071 was compared to that of the conventional protein kinase C (PKC) inhibitor Gö6850 (which, like sotrastaurin, inhibits classical and novel PKC isoforms), Gö6976 (an inhibitor of α and β PKC isoforms) and rottlerin (a prevailing δ PKC isoform inhibitor), AEB071 at an equimolar concentration of 3 μM (close to the maximum drug concentration reached in patients treated with AEB071) caused significantly more inhibition on both chemotactic response and superoxide production. These in vitro findings suggest that neutrophils may offer a cellular target for AEB071 activity in vivo