303 research outputs found

    Point-Like Graviton Scattering in Plane-Wave Matrix Model

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    In a plane-wave matrix model we discuss a two-body scattering of gravitons in the SO(3) symmetric space. In this case the graviton solutions are point-like in contrast to the scattering in the SO(6) symmetric space where spherical membranes are interpreted as gravitons. We concentrate on a configuration in the 1-2 plane where a graviton rotates with a constant radius and the other one elliptically rotates. Then the one-loop effective action is computed by using the background field method. As the result, we obtain the 1/r^7-type interaction potential, which strongly suggests that the scattering in the matrix model would be closely related to that in the light-front eleven-dimensional supergravity.Comment: 17 pages, 1 figure, LaTeX, v2) references adde

    The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression

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    The Mre11 complex (Mre11, Rad50, and Nbs1) is integral to both DNA repair and ataxia telangiectasia mutated (ATM)-dependent DNA damage signaling. All three Mre11 complex components are essential for viability at the cellular and organismal levels. To delineate essential and non-essential Mre11 complex functions that are mediated by Nbs1, we used TALEN-based genome editing to derive Nbs1 mutant mice (Nbs1mid mice), which harbor mutations in the Mre11 interaction domain of Nbs1. Nbs1mid alleles that abolished interaction were incompatible with viability. Conversely, a 108-amino-acid Nbs1 fragment comprising the Mre11 interface was sufficient to rescue viability and ATM activation in cultured cells and support differentiation of hematopoietic cells in vivo. These data indicate that the essential role of Nbs1 is via its interaction with Mre11 and that most of the Nbs1 protein is dispensable for Mre11 complex functions and suggest that Mre11 and Rad50 directly activate ATM

    Prognostic Value of Electrophysiological Parameters for the Recovery of Motor Functions in Stroke Patients

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    We estimated correlations between baseline electrophysiological parameters and motor functions in patients with subacute stroke, in order to identify their predictive value for motor and functional recovery after a 4-week-long rehabilitation period. Sixty patients with subacute stroke were enrolled. Somatosensory evoked potentials (SSEPs), compound motor action potentials (CMAPs), and sensory nerve action potentials (SNAPs) were recorded, and the amplitude ratios were calculated in the components of these potentials. Clinical parameters consisted of the Korean-modified Barthel index (K-MBI), motricity index (MI), and manual function test (MFT). After the rehabilitation period, these indices were re-evaluated. The ulnar CMAP amplitude was found to significantly correlate with all clinical outcome indices. Additionally, a multivariate linear regression analysis revealed that the ulnar CAMP amplitude ratio was an independent predictor for the baseline MI of the upper extremity and K-MBI. The median SSEP amplitude ratio was an independent prognostic factor for the follow-up MI of the upper extremity, MFT, and follow-up K-MBI. Our results indicate that not only is the median SSEP amplitude ratio a prognostic factor for the motor functions and functional recovery, but also the ulnar CMAP amplitude might be an independent predictor in subacute stroke patients.Ми оцінювали кореляції між вихідними електрофізіологічними параметрами та моторними функціями у пацієнтів із підгострим інсультом з ціллю ідентифікувати прогностичну цінність цих даних для моторного та функціонального відновлення після чотиритижневого періоду реабілітації. Відводили соматосенсорні викликані потенціали (SSEP), складні моторні потенціали дії (CMAP) та складні сенсорні нервові потенціали дії (SNAP); розраховували відношення амплітуд цих потенціалів та їх компонентів. Серед клінічних параметрів оцінювали індекс Бартела, модифікований для умов Кореї (K-MBI), індекс моторної сфери (MI) та тест мануальних функцій (MFT). Ці індекси повторно оцінювалися після періоду реабілітації. Амплітуда CMAP, викликаних стимуляцією ульнарного нерва, вірогідно корелювала з усіма клінічними показниками. Крім того, аналіз мультиваріативної лінійної регресії показав, що відношення амплітуд ульнарних CAMP є незалежним предиктором вихідного MI для верхньої кінцівки та K-MBI. Відношення амплітуд SSEP, викликаних стимуляцією медіанного нерва, було незалежним прогностичним фактором для післяреабілітаційного MI верхніх кінцівок, MFT і післяреабілітаційного K-MBI. Наші результати свідчать про те, що не тільки відношення амплітуд медіанних SSEP є прогностичним фактором щодо моторних функцій та функціонального відновлення; амплітуда ульнарних CMAP теж може бути незалежним предиктором у пацієнтів із підгострим інсультом

    Structural and dielectric properties of Sr2_{2}TiO4_{4} from first principles

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    We have investigated the structural and dielectric properties of Sr2_{2}TiO4_{4},the first member of the Srn+1_{n+1}Tin_{n}O3n+1_{3n+1} Ruddlesden-Popper series, within density functional theory. Motivated by recent work in which thin films of Sr2_{2}TiO4_{4} were grown by molecular beam epitaxy (MBE) on SrTiO3_{3} substrates, the in-plane lattice parameter was fixed to the theoretically optimized lattice constant of cubic SrTiO3_{3} (n=\infty), while the out-of-plane lattice parameter and the internal structural parameters were relaxed. The fully relaxed structure was also investigated. Density functional perturbation theory was used to calculate the zone-center phonon frequencies, Born effective charges, and the electronic dielectric permittivity tensor. A detailed study of the contribution of individual infrared-active modes to the static dielectric permittivity tensor was performed. The calculated Raman and infrared phonon frequencies were found to be in agreement with experiment where available. Comparisons of the calculated static dielectric permittivity with experiments on both ceramic powders and epitaxial thin films are discussed.Comment: 11 pages, 1 figure, 8 tables, submitted to Phys. Rev.

    Supersymmetry and Branes in M-theory Plane-waves

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    We study brane embeddings in M-theory plane-waves and their supersymmetry. The relation with branes in AdS backgrounds via the Penrose limit is also explored. Longitudinal planar branes are originated from AdS branes while giant gravitons of AdS spaces become spherical branes which are realized as fuzzy spheres in the massive matrix theory.Comment: 17 pages, JHEP style, references added, typos correcte

    AdS and pp-wave D-particle superalgebras

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    We derive anticommutators of supercharges with a brane charge for a D-particle in AdS(2) x S(2) and pp-wave backgrounds. A coset GL(2|2)/(GL(1))^4 and its Penrose limit are used with the supermatrix-valued coordinates for the AdS and the pp-wave spaces respectively. The brane charges have position dependence, and can be absorbed into bosonic generators by shift of momenta which results in closure of the superalgebras.Comment: 15 page

    Landscape Design for Improved Thermal Environment: An Optimized Tree Arrangement Design for Climate-Responsive Outdoor Spaces in Residential Buildings Complexes

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    The heat reduction effect of trees has been investigated through numerical simulations; however, there are still challenges to applying the scientific results to the planning process due to the model's complexity and the computational resources required. This study investigates a rapid spatial evaluation method for heat stress potential, measured by mean radiant temperature (MRT), by decomposing radiation into sub-radiation using a multilayer MRT model. This method also enables the reproduction of optimized layouts considering the effect of tree arrangement in residential buildings. Multi-objectives were achieved through an evolutionary algorithm, resulting in more effective design layouts combining tree types and arrangements, all within a standard budget. By adopting this study's approach, landscape designers can create climate-responsive tree layouts with reduced heat exposure and generate customized planting designs tailored to their preferences

    Spin Chains in N=6 Superconformal Chern-Simons-Matter Theory

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    In this note we study spin chain operators in the N=6 Chern-Simons-matter theory recently proposed by Aharony, Bergman, Jafferis and Maldacena to be dual to type IIA string theory in AdS4xCP3. We study the two-loop dilatation operator in the gauge theory, and compare to the Penrose limit on the string theory side.Comment: 19 pages, 15 figures; minor corrections, references adde
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