1,822 research outputs found

    A COMPARISON OF THE CULTURAL/ETHNIC PERCEPTIONS AND EDUCATIONAL BELIEFS OF KOREAN IMMIGRANT AND NON-IMMIGRANT FAMILIES

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    As a critical unit for identifying family-constructed meanings of education, a deeper contextual understanding of Korean immigrant parents\u27 cultural/ethnic perceptions in relation to educational beliefs should be central to culturally responsive education designed to support Korean immigrant families. It is necessary for educators to examine the beliefs and practices of Korean immigrant families around education in order to broaden the educational conversation and mutual understanding between parents and teachers for effectively facilitating their children\u27s learning and socialization. The purpose of this dissertation is to investigate the variations in cultural/ethnic perceptions and educational beliefs about childrearing and early schooling among three Korean parent groups: (a) 79 Korean immigrant parents in the U.S., (b) 98 Korean parents with no transnational experiences outside of the country of origin, Korea, and (c) 42 transnational parents in Korea who have returned from the U.S. to Korea. It examined the relationships between cultural/ethnic factors and Korean parents\u27 educational beliefs about young children\u27s learning and socialization. This study was a mixed methods design. Research findings from the quantitative survey data indicate several significant intracultural variations in cultural/ethnic perceptions and educational beliefs and noteworthy relationships among variables (e.g., between socio-demographic factors and acculturation, between enculturation and educational beliefs, etc.). Probing further through interviews, this study qualitatively explored four Korean immigrant parents\u27 cultural/ethnic experiences with their children\u27s schooling to raise additional questions regarding beliefs, attitudes, and values emerging in daily family lives. The findings indicate that Korean immigrant families encounter dual processes of acculturation and enculturation, that is, integration rather than assimilation, that can be potentially challenging for facilitating their children\u27s learning and socialization. (Cho, Chen, & Shin, 2010; Miyoshi, 2011; Song, 2010). The findings suggest that Korean immigrant families develop particular culture-belief structures derived from experiences of socio-cultural transformations between their own socio-cultural contexts and the mainstream school settings of their children. This study provides a critical foundation for a contextual understanding of Korean immigrant parents\u27 educational beliefs and practices related to early school schooling while being acculturated into the dominant school culture and curriculum. The implications are discussed for culturally responsive education

    Mitsugumin-29 Regulates RyR1 Activity In Mouse Skeletal Myotubes

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    Bright color optical switching device by polymer network liquid crystal with a specular reflector

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    The color optical switching device by polymer network liquid crystal (PNLC) with color filter on a specular reflector shows excellent performance; white reflectance of 22%, color gamut of 32%, and contrast ratio up to 50:1 in reflective mode measurement. The view-angle dependence of the reflectance can be adjusted by changing the PNLC thickness. The color chromaticity shown by the device is close to the limit value of color filters, and its value nearly remains with respect to the operating voltage. These optical properties of the device can be explained from the prediction based on multiple interactions between the light and the droplets of liquid crystal. The high reflectance, vivid color image, and moderate responds time allow the PNLC device to drive good color moving image. It can widely extend the applications of the reflective device. © 2011 Optical Society of America.1

    Korean Home Learning Environment and Parent Characteristics Influencing Children\u27s Expressive and Receptive Language Abilities

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    This study analyzed data derived from ‘The Panel Study on Korean Children’ implemented by the Korea Institute of Child Care & Education (KICCE). Two scales, EC-HOME and REVT were used to investigate specific types of home environments and parent characteristics beneficial in the facilitation of children’s receptive and expressive language development. The Step-wise Multiple Regression Analysis identified four variables (Responsively, Physical Environment, Father Education, and Mother Habitation) that made a significant contribution to children’s receptive language development, and six different variables (Mother Education, Academic Stimulation, and Physical Environment, Acceptance, Mother’s Current Job Status, and Communicative Stimulation) for expressive language development. This study found that home learning environment is a more significant factor for children\u27s receptive and expressive language development than parent demographic characteristics with the exception of the education level of parents, current job status of the mother, and habitation status of the mother

    Transplantation of Adipose Derived Stromal Cells into the Developing Mouse Eye

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    Adipose derived stromal cells (ADSCs) were transplanted into a developing mouse eye to investigate the influence of a developing host micro environment on integration and differentiation. Green fluorescent protein-expressing ADSCs were transplanted by intraocular injections. The age of the mouse was in the range of 1 to 10 days postnatal (PN). Survival dates ranged from 7 to 28 post transplantation (DPT), at which time immunohistochemistry was performed. The transplanted ADSCs displayed some morphological differentiations in the host eye. Some cells expressed microtubule associated protein 2 (marker for mature neuron), or glial fibrillary acid protein (marker for glial cell). In addition, some cells integrated into the ganglion cell layer. The integration and differentiation of the transplanted ADSCs in the 5 and 10 PN 7 DPT were better than in the host eye the other age ranges. This study was aimed at demonstrating how the age of host micro environment would influence the differentiation and integration of the transplanted ADSCs. However, it was found that the integration and differentiation into the developing retina were very limited when compared with other stem cells, such as murine brain progenitor cell

    Association Kikuchi disease with Hashimoto thyroiditis: a case report and literature review

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    Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease characterized by fever and lymphadenopathy. The etiology of KFD is unknown, but an autoimmune cause has been suggested. Hashimoto thyroiditis is the most common autoimmune thyroid disorder in children and is known to be associated with other autoimmune diseases. Only a few cases of Hashimoto thyroiditis associated with KFD have been documented. We report a case of a 16-year-old girl who was first diagnosed with KFD and developed Hashimoto thyroiditis 2 years and 6 months later during her follow-up period. Physicians of patients with KFD should consider the possibility of autoimmune diseases like Hashimoto’s thyroiditis

    Effect of moderate-intensity statin therapy on plaque inflammation in patients with acute coronary syndrome: A prospective interventional study evaluated by 18F-FDG PET/CT of the carotid artery

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    Background: Asian patients with acute coronary syndrome (ACS) are frequently prescribed moderate- -intensity statin in real practice, even during the early stage of ACS. Under assessment herein was the effect of moderate-intensity statin therapy on the resolution of plaque inflammation during the first month after ACS, a period with highest recurrent ischemic events, using dual time point 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT).Methods: This prospective study included statin-naïve patients with ACS and non-calcified carotid plaques (≥ 3 mm on ultrasound images). Baseline FDG PET/CT images of the carotid arteries of the patients were obtained. Then, all patients received atorvastatin (20 mg/day); follow-up FDG PET/CT images of the carotid arteries were then obtained after 1 month of therapy. The primary endpoint measurement was the change in the target-to-background ratio (TBR) of the carotid artery between the initial and follow-up FDG PET/CT scans.Results: Thirteen ACS patients completed the initial and follow-up FDG PET/CT scans. Moderate-intensity statin therapy failed to reduce plaque inflammation at 1 month after ACS (TBR 1.60 ± 0.20 at baseline vs. 1.50 ± 0.40 after therapy; p = 0.422) but significantly reduced serum low-density lipoprotein cholesterol (LDL-C) levels (mean LDL-C 101.2 ± 21.1 mg/dL at baseline vs. 70.7 ± 12.4 mg/dL after therapy; p < 0.001). Changes in the TBR and serum LDL-C levels were not correlated (r = –0.27, p = 0.243).Conclusions: Dual time point FDG PET/CT imaging demonstrates that moderate-intensity statin therapy was insufficient in suppressed plaque inflammation within the first month after ACS in Asian patients, even though achieving target LDL levels

    Overexpression of the miR-141/200c cluster promotes the migratory and invasive ability of triple-negative breast cancer cells through the activation of the FAK and PI3K/AKT signaling pathways by secreting VEGF-A

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    Migration in miR-141/200c-transduced HCC-38 and Hs578T cells treated with an anti-VEGF-A-neutralizing antibody. (A, D) Migration in miR-141/200c-transduced HCC-38 and Hs578T cells. Images of the crystal violet-stained cells that migrated horizontally in the trans-well migration assay (upper). The absorbance values of extracted crystal violet in migrated cells (lower). The migratory abilities of the miR-200c cells (~1.6-fold and ~1.7-fold, HCC-38 and Hs578T, respectively) were significantly increased compared with those of the control cells. (B, E) Measurement of the secreted levels of cytokines and growth factors (IL-2, IL-4, IL-5, IL-10, IL-12, IL-13, GM-CSF, IFN-γ, TNF-α, and VEGF-A). Transduction of miR-141/200c into HCC-38 and Hs578T cells promoted significantly higher VEGF-A secretion than that of control cells. (C, F) Trans-well migration of anti-VEGF-A-neutralizing antibody-treated cells. The enhanced migration of the miR-141/200c-transduced HCC-38 cells were significantly suppressed by treatment with anti-VEGF-A-neutralizing antibodies, but miR-141/200c-transduced Hs578T cells still showed increased migratory ability compared with control cells. *p < 0.05, **p < 0.001. (JPG 188 kb

    Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.

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    Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone formation through phosphorylation of serine 14 (S14) on Inhibitor of DNA binding 2 (Id2). This enhances Id2 protein stability by means of escape from proteasomal degradation, and steers its localization to the growth cone, where Id2 interacts with radixin that is critical for growth cone formation. Knockdown of Id2, or abrogation of Id2 phosphorylation at S14, greatly impairs axon growth and the architecture of growth cone. Intriguingly, reinstatement of Akt/Id2 signaling after injury in mouse hippocampal slices redeemed growth promoting ability, leading to obvious axon regeneration. Our results suggest that Akt/Id2 signaling is a key module for growth cone formation and axon growth, and its augmentation plays a potential role in CNS axonal regeneration

    Electroacupuncture Delays Hypertension Development through Enhancing NO/NOS Activity in Spontaneously Hypertensive Rats

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    Using spontaneously hypertensive rats (SHR), this study investigated whether electroacupuncture (EA) could reduce early stage hypertension by examining nitric oxide (NO) levels in plasma and nitric oxide synthase (NOS) levels in the mesenteric resistance artery. EA was applied to the acupuncture point Governor Vessel 20 (GV20) or to a non-acupuncture point in the tail twice weekly for 3 weeks under anesthesia. In conscious SHR and normotensive Wistar Kyoto (WKY) rats, blood pressure was determined the day after EA treatment by the tail-cuff method. We measured plasma NO concentration, and evaluated endothelial NO syntheses (eNOS) and neuronal NOS (nNOS) protein expression in the mesenteric artery. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were lower after 3 weeks of GV20 treatment than EA at non-acupuncture point and no treatment control in SHR. nNOS expression by EA was significantly different between both WKY and no treatment SHR control, and EA at GV20 in SHR. eNOS expression was significantly high in EA at GV 20 compared with no treatment control. In conclusion, EA could attenuate the blood pressure elevation of SHR, along with enhancing NO/NOS activity in the mesenteric artery in SHR
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