6,650 research outputs found
Review of Privileged Documents in Trial and Deposition Preparation of Witnesses in New York: When, if Ever, Will the Privilege be Lost?
This article will examine New York’s refreshing recollection doctrine in the context of trial and deposition preparation of witnesses as to the consequences of the witness’s review of privileged writings. Initially, Part II will discuss Rule 612 of the Federal Rules of Evidence. The discussion will serve as the backdrop for the analysis of the above-mentioned issues under New York law. Part III will then examine the refreshing recollection doctrine as developed and applied to testifying witnesses at a trial or deposition by the New York courts. The examination will point out the doctrine’s key rules. Part IV discusses the treatment of these key rules by the New York courts in the witness preparation situation, both pre-trial and pre-deposition, showing the shortcomings of this judicial treatment and advocating for change. Lastly, Part V makes some suggestions to the attorney in light of current New York law as to avoidance in the preparation of witnesses before they testify at a trial or a deposition of the disclosure of otherwise privileged writings
CFT Duals for Extreme Black Holes
It is argued that the general four-dimensional extremal Kerr-Newman-AdS-dS
black hole is holographically dual to a (chiral half of a) two-dimensional CFT,
generalizing an argument given recently for the special case of extremal Kerr.
Specifically, the asymptotic symmetries of the near-horizon region of the
general extremal black hole are shown to be generated by a Virasoro algebra.
Semiclassical formulae are derived for the central charge and temperature of
the dual CFT as functions of the cosmological constant, Newton's constant and
the black hole charges and spin. We then show, assuming the Cardy formula, that
the microscopic entropy of the dual CFT precisely reproduces the macroscopic
Bekenstein-Hawking area law. This CFT description becomes singular in the
extreme Reissner-Nordstrom limit where the black hole has no spin. At this
point a second dual CFT description is proposed in which the global part of the
U(1) gauge symmetry is promoted to a Virasoro algebra. This second description
is also found to reproduce the area law. Various further generalizations
including higher dimensions are discussed.Comment: 18 pages; v2 minor change
Remotely operated gripper provides vertical control rod movement
Remote actuation of a gripper shaft affects vertical engagement between a drive shaft and control rod. A secondary function of the gripper is to provide remote indication of positive completion of the gripping or ungripping operation
MDL Convergence Speed for Bernoulli Sequences
The Minimum Description Length principle for online sequence
estimation/prediction in a proper learning setup is studied. If the underlying
model class is discrete, then the total expected square loss is a particularly
interesting performance measure: (a) this quantity is finitely bounded,
implying convergence with probability one, and (b) it additionally specifies
the convergence speed. For MDL, in general one can only have loss bounds which
are finite but exponentially larger than those for Bayes mixtures. We show that
this is even the case if the model class contains only Bernoulli distributions.
We derive a new upper bound on the prediction error for countable Bernoulli
classes. This implies a small bound (comparable to the one for Bayes mixtures)
for certain important model classes. We discuss the application to Machine
Learning tasks such as classification and hypothesis testing, and
generalization to countable classes of i.i.d. models.Comment: 28 page
Offline to Online Conversion
We consider the problem of converting offline estimators into an online
predictor or estimator with small extra regret. Formally this is the problem of
merging a collection of probability measures over strings of length 1,2,3,...
into a single probability measure over infinite sequences. We describe various
approaches and their pros and cons on various examples. As a side-result we
give an elementary non-heuristic purely combinatoric derivation of Turing's
famous estimator. Our main technical contribution is to determine the
computational complexity of online estimators with good guarantees in general.Comment: 20 LaTeX page
Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones
Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood. The differentiation of stem cells after leaving their niches depends predominately on the local milieu and its new microenvironment, and is facilitated by soluble factors but also by the close cell-cell interaction in a three-dimensional tissue or organ system. We have isolated CD34-negative, mesenchymal stem cell lines from human bone marrow and peripheral blood and generated monoclonal cell populations after immortalization with the SV40 large T-antigen. The cultivation of those adult stem cell clones in an especially designed in vitro environment, including self-constructed glass capillaries with defined growth conditions, leads to the spontaneous establishment of pleomorphic three-dimensional cell aggregates ( spheroids) from the monoclonal cell population, which consist of cells with an osteoblast phenotype and areas of mineralization along with well-vascularized tissue areas. Modifications of the culture conditions favored areas of bone-like calcifications. After the transplantation of the at least partly mineralized human spheroids into different murine soft tissue sites but also a dorsal skinfold chamber, no further bone formation could be observed, but angiogenesis and neovessel formation prevailed instead, enabling the transplanted cells and cell aggregates to survive. This study provides evidence that even monoclonal adult human CD34-negative stem cells from the bone marrow as well as peripheral blood can potentially differentiate into different mesenchymal tissues depending on the local milieu and responding to the needs within the microenvironment. Copyright (C) 2005 S. Karger AG, Basel
Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy
Dynamic visualization of the intravascular events leading to the extravasation of leukocytes into tissues by intravital microscopy has significantly expanded our understanding of the underlying molecular processes. In contrast, the detailed observation of leukocyte transendothelial and interstitial migration in vivo has been hampered by the poor image contrast of cells within turbid media that is obtainable by conventional brightfield microscopy. Here we present a microscopic method, termed reflected light oblique transillumination microscopy, that makes use of the optical interference phenomena generated by oblique transillumination to visualize subtle gradients of refractive indices within tissues for enhanced image contrast. Using the mouse cremaster muscle, we demonstrate that this technique makes possible the reliable quantification of extravasated leukocytes as well as the characterization of morphological phenomena of leukocyte transendothelial and interstitial migration
Indefinitely Oscillating Martingales
We construct a class of nonnegative martingale processes that oscillate
indefinitely with high probability. For these processes, we state a uniform
rate of the number of oscillations and show that this rate is asymptotically
close to the theoretical upper bound. These bounds on probability and
expectation of the number of upcrossings are compared to classical bounds from
the martingale literature. We discuss two applications. First, our results
imply that the limit of the minimum description length operator may not exist.
Second, we give bounds on how often one can change one's belief in a given
hypothesis when observing a stream of data.Comment: ALT 2014, extended technical repor
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