Uncertainties of predictions from parton distribution functions II: the Hessian method

We develop a general method to quantify the uncertainties of parton distribution functions and their physical predictions, with emphasis on incorporating all relevant experimental constraints. The method uses the Hessian formalism to study an effective chi-squared function that quantifies the fit between theory and experiment. Key ingredients are a recently developed iterative procedure to calculate the Hessian matrix in the difficult global analysis environment, and the use of parameters defined as components along appropriately normalized eigenvectors. The result is a set of 2d Eigenvector Basis parton distributions (where d=16 is the number of parton parameters) from which the uncertainty on any physical quantity due to the uncertainty in parton distributions can be calculated. We illustrate the method by applying it to calculate uncertainties of gluon and quark distribution functions, W boson rapidity distributions, and the correlation between W and Z production cross sections.Comment: 30 pages, Latex. Reference added. Normalization of Hessian matrix changed to HEP standar

A Sequential Model of Host Cell Killing and Phagocytosis by Entamoeba histolytica

The protozoan parasite Entamoeba histolytica is responsible for invasive intestinal and extraintestinal amebiasis. The virulence of Entamoeba histolytica is strongly correlated with the parasite's capacity to effectively kill and phagocytose host cells. The process by which host cells are killed and phagocytosed follows a sequential model of adherence, cell killing, initiation of phagocytosis, and engulfment. This paper presents recent advances in the cytolytic and phagocytic processes of Entamoeba histolytica in context of the sequential model

Bohemianism and Urban Regeneration: A Structured Literature Review and Compte Rendu

Despite a burgeoning literature, the role of bohemians in the urban milieu and in initiatives toward regeneration remains contested. As a first step toward later modeling and application, we present a thoroughgoing literature review, a short commentary on bohemian phenomena, and suggested readings. Since qualitative sources dominate the field, the review is structured rather than fully systematic in the scientific sense. After discarding innumerable irrelevant and incidental papers, three strands remained for subsequent analysis: “bohemian,” “bohemian + creative-city,” and “smart regeneration.” The first is static or historically contextualized, situated best in the humanities. The last two strands are dynamic and dissect, descriptively or analytically, elements of bohemianism relevant to the urban scene. Wherever and whenever they emerge, radical bohemian artists test existing limits or incite transformative action

Animal Models of Human Systemic Lupus Erythematosus 1

Systemic lupus erythematosus (SLE) is a human autoimmune disease of unknown etiology. Clinical, serologic, immunologic, and pathologic findings are highly variable in different patients and at different times in the same patient. Murine and canine animal models of SLE have been found with clinicopathologic abnormalities resembling those observed in humans. Each animal model has unique characteristics; taken together they reflect the spectrum of disease in human SLE

Stability of NLO Global Analysis and Implications for Hadron Collider Physics

The phenomenology of Standard Model and New Physics at hadron colliders depends critically on results from global QCD analysis for parton distribution functions (PDFs). The accuracy of the standard next-to-leading-order (NLO) global analysis, nominally a few percent, is generally well matched to the expected experimental precision. However, serious questions have been raised recently about the stability of the NLO analysis with respect to certain inputs, including the choice of kinematic cuts on the data sets and the parametrization of the gluon distribution. In this paper, we investigate this stability issue systematically within the CTEQ framework. We find that both the PDFs and their physical predictions are stable, well within the few percent level. Further, we have applied the Lagrange Multiplier method to explore the stability of the predicted cross sections for W production at the Tevatron and the LHC, since W production is often proposed as a standard candle for these colliders. We find the NLO predictions on sigma_W to be stable well within their previously-estimated uncertainty ranges.Comment: 24 pages, 11 figures. Minor changes in response to JHEP referee repor

Neutrino Dimuon Production and the Strangeness Asymmetry of the Nucleon

We have performed the first global QCD analysis to include the CCFR and NuTeV dimuon data, which provide direct constraints on the strange and anti-strange parton distributions, $s(x)$ and $\bar{s}(x)$. To explore the strangeness sector, we adopt a general parametrization of the non-perturbative $s(x), \bar{s}(x)$ functions satisfying basic QCD requirements. We find that the strangeness asymmetry, as represented by the momentum integral $[S^{-}]\equiv \int_0^1 x [s(x)-\bar{s}(x)] dx$, is sensitive to the dimuon data provided the theoretical QCD constraints are enforced. We use the Lagrange Multiplier method to probe the quality of the global fit as a function of $[S^-]$ and find $-0.001 < [S^-] < 0.004$. Representative parton distribution sets spanning this range are given. Comparisons with previous work are made.Comment: 23 pages, 4 figures; expanded version for publicatio