CTEQ-TEA parton distribution functions with intrinsic charm

The possibility of a (sizable) nonperturbative contribution to the charm parton distribution function (PDF) in a nucleon is investigated together with theoretical issues arising in its interpretation. Results from the global PDF analysis are presented. The separation of the universal component of the nonperturbative charm from the rest of the radiative contributions is discussed and the potential impact of a nonperturbative charm PDF on LHC scattering processes is illustrated. An estimate of nonperturbative charm magnitude in the CT14 and CT14HERA2 global QCD analyses at the next-to-next-to leading order (NNLO) in the QCD coupling strength is given by including the latest experimental data from HERA and the Large Hadron Collider (LHC). A comparison between different models of intrinsic charm is shown and prospects for standard candle observables at the LHC are illustrated.Comment: 7 pages, 2 figures. Conference Proceedings of CIPANP2018, 13th Conference on the Intersections of Particle and Nuclear Physics, May 29 - June 3, 2018 Palm Springs, CA. Based on arXiv: 1707.00657, published in JHEP 1802 (2018) 05

CTEQ-TEA Parton Distributions Functions with Intrinsic Charm

We present a study in which the possibility of a (sizable) nonperturbative contribution to the charm parton distribution function (PDF) in a nucleon is investigated together with theoretical issues arising in its interpretation. The separation of the universal component of the nonperturbative charm from the rest of the radiative contributions is also discussed. We illustrate the potential impact of a nonperturbative charm PDF on LHC scattering processes. An estimate of nonperturbative charm magnitude in the CT14 and CT14HERA2 global QCD analyses at the next-to-next-to leading order (NNLO) in the QCD coupling strength is given by including the latest experimental data from HERA and the Large Hadron Collider. We show a comparison between different models of intrinsic charm and illustrate prospects for standard candle observables at the LHC

CTEQ-TEA parton distribution functions with intrinsic charm

We present a study in which the possibility of a (sizable) nonperturbative contribution to the charm parton distribution function (PDF) in a nucleon is investigated together with theoretical issues arising in its interpretation. The separation of the universal component of the nonperturbative charm from the rest of the radiative contributions is also discussed. We illustrate the potential impact of a nonperturbative charm PDF on LHC scattering processes. An estimate of nonperturbative charm magnitude in the CT14 and CT14HERA2 global QCD analyses at the next-to-next-to leading order (NNLO) in the QCD coupling strength is given by including the latest experimental data from HERA and the Large Hadron Collider. We show a comparison between different models of intrinsic charm and illustrate prospects for standard candle observables at the LHC

Ratification of the Base of the ICS Geological Time Scale: The Global Standard Stratigraphic Age (GSSA) for the Hadean Lower Boundary

The base of the ICS (International Commission on Stratigraphy) Geological Time Scale was ratified in 2022 by defining a new Global Stratigraphic Standard Age (GSSA) for the lower boundary of the Hadean Eon (formerly 4000-3600 Ma); the age of the Solar System based on the oldest solids, calcium-aluminium inclusions (CAIs), generated in the protoplanetary disk. The formal GSSA for the Hadean base is the oldest reliable, weighted mean U-corrected Pb-Pb age of 4567.30 ± 0.16 Ma obtained for CAIs in primitive meteorites Allende and Efremovka. This age is supported by the 4568-4567 Ma U-corrected Pb-Pb ages of chondrules in Northwest African meteorites. The boundary sets an upper lifetime for the protoplanetary disk and timing of planet formation. The Hadean Eon encloses the accretion and differentiation of the Earth and other planets, the Moon-forming Giant Impact, the beginning of the suggested Late Heavy Bombardment, and the formation of the Earth\u27s protocrust. Due to the Moon-forming Giant Impact that occurred after the differentiation of the proto-Earth and the fact that Earth\u27s first crust has been destroyed, the age of the planet Earth itself remains an open question. However, many pieces of astronomical, chemical, physical, and chronological evidence point to the very fast formation of the Solar System and rapid accretion and differentiation of the proto-Earth in only a few million years. Compared to the half-billion-year duration of the Hadean, it is reasonable to set the age of the Earth at the beginning of the formation of the Solar System. This communication explains and justifies the selection of the GSSA for the Hadean base

Effects of Vagus Nerve Stimulation and Vagotomy on Systemic and Pulmonary Inflammation in a Two-Hit Model in Rats

Pulmonary inflammation contributes to ventilator-induced lung injury. Sepsis-induced pulmonary inflammation (first hit) may be potentiated by mechanical ventilation (MV, second hit). Electrical stimulation of the vagus nerve has been shown to attenuate inflammation in various animal models through the cholinergic anti-inflammatory pathway. We determined the effects of vagotomy (VGX) and vagus nerve stimulation (VNS) on systemic and pulmonary inflammation in a two-hit model. Male Sprague-Dawley rats were i.v. administered lipopolysaccharide (LPS) and subsequently underwent VGX, VNS or a sham operation. 1 hour following LPS, MV with low (8 mL/kg) or moderate (15 mL/kg) tidal volumes was initiated, or animals were left breathing spontaneously (SP). After 4 hours of MV or SP, rats were sacrificed. Cytokine and blood gas analysis was performed. MV with 15, but not 8 mL/kg, potentiated the LPS-induced pulmonary pro-inflammatory cytokine response (TNF-α, IL-6, KC: p<0.05 compared to LPS-SP), but did not affect systemic inflammation or impair oxygenation. VGX enhanced the LPS-induced pulmonary, but not systemic pro-inflammatory cytokine response in spontaneously breathing, but not in MV animals (TNF-α, IL-6, KC: p<0.05 compared to SHAM), and resulted in decreased pO2 (p<0.05 compared to sham-operated animals). VNS did not affect any of the studied parameters in both SP and MV animals. In conclusion, MV with moderate tidal volumes potentiates the pulmonary inflammatory response elicited by systemic LPS administration. No beneficial effects of vagus nerve stimulation performed following LPS administration were found. These results questions the clinical applicability of stimulation of the cholinergic anti-inflammatory pathway in systemically inflamed patients admitted to the ICU where MV is initiated

Ratification of the base of the ICS Geological Time Scale : the Global Standard Stratigraphic Age (GSSA) for the Hadean lower boundary

Peer reviewe

Ratification of the base of the ICS Geological Time Scale: the Global Standard Stratigraphic Age (GSSA) for the Hadean lower boundary

The base of the ICS (International Commission on Stratigraphy) Geological Time Scale was ratified in 2022 by defining a new Global Stratigraphic Standard Age (GSSA) for the lower boundary of the Hadean Eon (formerly 4000–3600 Ma); the age of the Solar System based on the oldest solids, calcium-aluminium inclusions (CAIs), generated in the protoplanetary disk. The formal GSSA for the Hadean base is the oldest reliable, weighted mean Ucorrected Pb–Pb age of 4567.30 ± 0.16 Ma obtained for CAIs in primitive meteorites Allende and Efremovka. This age is supported by the 4568–4567 Ma U-corrected Pb–Pb ages of chondrules in Northwest African meteorites. The boundary sets an upper lifetime for the protoplanetary disk and timing of planet formation. The Hadean Eon encloses the accretion and differentiation of the Earth and other planets, the Moon-forming Giant Impact, the beginning of the suggested Late Heavy Bombardment, and the formation of the Earth’s protocrust. Due to the Moon-forming Giant Impact that occurred after the differentiation of the proto-Earth and the fact that Earth’s first crust has been destroyed, the age of the planet Earth itself remains an open question. However, many pieces of astronomical, chemical, physical, and chronological evidence point to the very fast formation of the Solar System and rapid accretion and differentiation of the proto-Earth in only a few million years. Compared to the half-billion-year duration of the Hadean, it is reasonable to set the age of the Earth at the beginning of the formation of the Solar System. This communication explains and justifies the selection of the GSSA for the Hadean base

recent progress in higher order computations for the physics of the higgs boson

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Are German patients burdened by the practice charge for physician visits ('Praxisgebuehr')? A cross sectional analysis of socio-economic and health related factors

<p>Abstract</p> <p>Background</p> <p>In 2004, a practice charge for physician visits ('Praxisgebuehr') was implemented in the German health care system, mainly in order to reduce expenditures of sickness funds by reducing outpatient physician visits. In the statutory sickness funds, all adults now have to pay € 10 at their first physician visit in each 3 month period, except for vaccinations and preventive services. This study looks at the effect of this new patient fee on delaying or avoiding physician visits, with a special emphasis on different income groups.</p> <p>Methods</p> <p>Six representative surveys (conducted between 2004 and 2006) of the Bertelsmann Healthcare Monitor were analysed, comprising 7,769 women and men aged 18 to 79 years. The analyses are based on stratified analyses and logistic regression models, including a focus on the subgroup having a chronic disease.</p> <p>Results</p> <p>Two results can be highlighted. First, avoiding or delaying a physician visit due to this fee is seen most often among younger and healthier adults. Second, those in the lowest income group are much more affected in this way than the better of. The multivariate analysis in the subgroup of respondents having a chronic disease shows, for example, that this reaction is reported 2.45 times more often in the lowest income group than in the highest income group (95% CI: 1.90–3.15).</p> <p>Conclusion</p> <p>The analyses indicate that the effects of the practice charge differ by socio-economic group. It would be important to assess these effects in more detail, especially the effects on health care quality and health outcomes. It can be assumed, however, that avoiding or delaying physician visits jeopardizes both, and that health inequalities are increasing due to the practice charge.</p

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure