Pola Warna Hasil Persilangan Kambing Boer dengan Kambing Jawarandu

: This research aims to know the pattern of Boerja goat color which is the result of the crossbreeding of Boer goats with Jawarandu goats. This research was conducted at the Edrian Bulle Farm, Lampung. The object of this research used livestock material of 303 Boerja goats which consists of 217 F1, 56 F2, 19 F3, and 11 F4. The parameters include the color composition of the body part Boerja goat. The data that has been collected is processed and analyzed descriptively. The result of this research illustrates that the color that appears in Boerja goat are brown and white. The Boerja goat has a brown and white head and neck, while the Boerja goat has white fur on the surface of the body, legs, and tail. In general, the Boerja goat's color is a combination of Jawarandu goat color that spread following the pattern of Boer goat color.: This research aims to know the pattern of Boerja goat color which is the result of the crossbreeding of Boer goats with Jawarandu goats. This research was conducted at the Edrian Bulle Farm, Lampung. The object of this research used livestock material of 303 Boerja goats which consists of 217 F1, 56 F2, 19 F3, and 11 F4. The parameters include the color composition of the body part Boerja goat. The data that has been collected is processed and analyzed descriptively. The result of this research illustrates that the color that appears in Boerja goat are brown and white. The Boerja goat has a brown and white head and neck, while the Boerja goat has white fur on the surface of the body, legs, and tail. In general, the Boerja goat's color is a combination of Jawarandu goat color that spread following the pattern of Boer goat color

Spontaneous imagined intergroup contact and intergroup relations: Quality matters

While research on experimental interventions that aim to improve outgroup attitudes via contact imagery grows, it is important to examine if contact imagery that occurs in spontaneous, non‐experimentally controlled conditions drives attitudes, and in what direction. To answer this, we constructed and validated a spontaneous imagined intergroup contact scale (SIICS) that differentiates between frequency, quality and elaboration of the spontaneous imagery of outgroups. In three correlational studies (NPortugal = 305, NUnited Kingdom = 185, NItaly = 276), we tested the role of spontaneous imagined contact frequency, quality and elaboration in predicting attitudes and social distance (Studies 1‐3) and intended behaviour (Study 3) toward immigrant groups. Results demonstrated that spontaneous imagined contact quality consistently predicted key outcome variables above and beyond the other two dimensions. Importantly, the effects were significant while controlling for other potent forms of direct and indirect contact. Implications of the findings for theory and practice are discussed

The week after:Do the effects of imagined contact last over time?

The vast majority of studies assessing the prejudice reduction properties of imagined contact have focused so far on the immediate effects of the intervention. In an attempt to contribute to the literature examining the long-term effects of imagined contact, the two studies reported in this paper tested the immediate and long-term effects of imagined contact on outgroup attitudes, intergroup anxiety, and behavioral intentions in Experiment 1, and also on contact self-efficacy in Experiment 2. Both studies were conducted in a context of entrenched intergroup conflict, Cyprus. The results supported the effectiveness of imagined contact in eliciting more positive attitudes, lower levels of anxiety, more positive behavioral intentions, and higher contact self-efficacy when these were measured immediately after contact. However, evidence for the endurance of these effects was systematically found only for outgroup attitudes and intergroup anxiety. While these results speak to the ability of imagined contact to lead to long-term changes in important and commonly studied intergroup outcomes, lack of consistent evidence regarding its ability to yield lasting changes on variables pertaining to intended behavior toward the outgroup compose a challenge for the intervention

Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries

It is crucial to understand why people comply with measures to contain viruses and their effects during pandemics. We provide evidence from 35 countries (Ntotal = 12,553) from 6 continents during the COVID-19 pandemic (between 2021 and 2022) obtained via cross-sectional surveys that the social perception of key protagonists on two basic dimensions—warmth and competence—plays a crucial role in shaping pandemic-related behaviors. Firstly, when asked in an open question format, heads of state, physicians, and protest movements were universally identified as key protagonists across countries. Secondly, multiple-group confirmatory factor analyses revealed that warmth and competence perceptions of these and other protagonists differed significantly within and between countries. Thirdly, internal meta-analyses showed that warmth and competence perceptions of heads of state, physicians, and protest movements were associated with support and opposition intentions, containment and prevention behaviors, as well as vaccination uptake. Our results have important implications for designing effective interventions to motivate desirable health outcomes and coping with future health crises and other global challenges.publishedVersio

Lymphatic mapping and sentinel node biopsy in gynecological cancers: a critical review of the literature

Although it does not have a long history of sentinel node evaluation (SLN) in female genital system cancers, there is a growing number of promising study results, despite the presence of some aspects that need to be considered and developed. It has been most commonly used in vulvar and uterine cervivcal cancer in gynecological oncology. According to these studies, almost all of which are prospective, particularly in cases where Technetium-labeled nanocolloid is used, sentinel node detection rate sensitivity and specificity has been reported to be 100%, except for a few cases. In the studies on cervical cancer, sentinel node detection rates have been reported around 80–86%, a little lower than those in vulva cancer, and negative predictive value has been reported about 99%. It is relatively new in endometrial cancer, where its detection rate varies between 50 and 80%. Studies about vulvar melanoma and vaginal cancers are generally case reports. Although it has not been supported with multicenter randomized and controlled studies including larger case series, study results reported by various centers around the world are harmonious and mutually supportive particularly in vulva cancer, and cervix cancer. Even though it does not seem possible to replace the traditional approaches in these two cancers, it is still a serious alternative for the future. We believe that it is important to increase and support the studies that will strengthen the weaknesses of the method, among which there are detection of micrometastases and increasing detection rates, and render it usable in routine clinical practice

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

CHEMICAL COMPOSITION AND ANTIBACTERIAL EVALUATION OF THE ESSENTIAL OILS OF FERULAGO AUCHERI BOISS. FROM DIFFERENT LOCALITIES

Air dried and crushed fruits of Ferulago aucheri Boiss. (Apiaceae) from Southern and Western regions of Turkey were subjected to hydrodistillation to obtain essential oils, which were subsequently analyzed by GC-FID and GC/MS. Seventy seven compounds representing 95.9% and 127 compounds representing 86.5% of the fruit oils have been characterized for samples of F. aucheri from Antalya (oil A) and Manisa (oil B) provinces, respectively. Monoterpenes comprised 83.6% of the oil A with limonene (43.1%), alpha-pinene (18.3%) and myrcene (7.0%) as major constituents. Sesquiterpenes (72.7%) prevailed in the oil B, with germacrene D (25.7%) and (2E,6E)-farnesol (8.0%) as major constituents. Both essential oils were also evaluated for their antibacterial activity against eight Gram (+) and Gram (-) strains by microdilution method. The oils displayed moderate to weak inhibitory activity (MIC 0.25-3 mg/mL). The oils were found to be the most active against Pseudomonas aeruginosa when compared with antimicrobial standards. Antibacterial activity of the oils appeared non-selective when comparing Gram (+) and Gram (-) strains