Persistence and Stability for a Generalized Leslie-Gower Model with Stage Structure and Dispersal

A generalized version of the Leslie-Gower predator-prey model that incorporates the prey structure and predator dispersal in two-patch environments is introduced. The focus is on the study of the boundedness of solution, permanence, and extinction of the model. Sufficient conditions for global asymptotic stability of the positive equilibrium are derived by constructing a Lyapunov functional. Numerical simulations are also presented to illustrate our main results

A preliminary study on the key factors contributing to the attractive lips of Chinese children

AbstractObjectiveTo explore the aesthetic characteristics of the Chinese children lips.MethodsFrontal and profile photographs of 653 healthy children were categorized as the attractive and the unattractive by three laypersons and objectively measured for comparison.ResultsThe attractive group tended to be smaller in the upper paramedian red lip height, the lower paramedian red lip height, the midline upper red lip height, the central bow angle, and the lip angle, while greater in the Cupid's bow width.ConclusionsThinner lips seemed to be more attractive than full ones among Chinese children

Effects of 3-Phenyl-Propenal on the Expression of Toll-Like Receptors and Downstream Signaling Components on Raw264.7 Murine Macrophages

Abstract: 3-phenyl-propenal is one of the principle compounds isolated from Guizhi (Ramulus Cinnamomi), the principal drug in Guizhi-Tang (GZT), a famous traditional Chinese medical formula. The aim of the present study was to investigate the effects of 3-phenyl-propenal on the expression of toll-like receptor 3 (TLR3), TLR4 and the downstream signaling components on Raw264.7 murine microphages. Raw264.7 cells were cultured in RPMI-1640 medium containing LPS (lipopolysaccharide) or poly (I:C) in the presence or absence of 3-phenyl-propenal. After 24-hour incubation, the medium was collected and the amount of TNF-α and IFN-β was measured by ELISA. mRNA expression of TLR3, TLR4, myeloid differentiation factor (MyD88), TRAF-6 (tumor necrosis factor receptor-associated), TRAM (toll-like receptor-associated molecule) and TRIF (TIR domain-containing adaptor inducing IFN-β) were analyzed by real-time PCR with SYBR green dye. Protein expression of TLR3 and TLR4 was analyzed by Western blotting and that of MyD88 and TRAF-6 was analyzed by immunofluorescence assay. The results indicate that LPS increased the expression of TLR4, MyD88, TRAF-6, TRAM and TRIF, but had no influence on TLR3, while poly (I:C) up-regulated the expression of TLR3, MyD88, TRAM and TRIF. 3-phenyl-propenal significantly decreased the expression of LPS-induced TLR4, MyD88, TRAF-6, while possessing no effect on LPS-induced TRAM and TRIF expression in Raw264.7 cells. When cells were stimulated by poly (I:C), 3-phenyl-propenal significantly decreased TLR3 and MyD88 expression. In conclusion, 3-phenyl-propenal blocked the over-expression of TLR3, TLR4, their downstream signaling components MyD88 and TRAF-6, which indicate that it had an antagonistic effect on TLR3 and TLR4

Cinnamaldehyde up-regulates the mRNA expression level of TRPV1 receptor potential ion channel protein and its function in primary rat DRG neurons in vitro

Cinnamaldehyde (1) is a pharmacologically active ingredient isolated from cassia twig (Ramulus Cinnamomi), which is commonly used in herbal remedies to treat fever-related diseases. Both TRPV1 and TRPM8 ion channel proteins are abundantly expressed in sensory neurons, and are assumed to act as a thermosensor, with the former mediating the feeling of warmth and the latter the feeling of cold in the body. Both of them have recently been reported to be involved in thermoregulation. The purpose of this paper is to further uncover the antipyretic mechanisms of 1 by investigating its effects on the mRNA expression levels and functions of both TRPV1 and TRPM8. The results showed that 1 could up-regulate the mRNA expression levels of TRPV1 at both 37 and 39 degrees C, and its calcium-mediating function was significantly increased at 39 degrees C, all of which could not be blocked by pretreatment of the neuronal cells with ruthenium red, a general transient receptor potential (TRP) blocker, indicating that the action of 1 was achieved through a non-TRPA1 channel pathway. In conclusion, the findings in our in vitro studies might account for part of the peripheral molecular mechanisms for the antipyretic action of 1

The Large Sky Area Multi-object Fiber Spectroscopic Telescope (LAMOST) Quasar Survey: Quasar Properties from Data Release Six to Nine

We report the fourth installment in the series of the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) Quasar Survey, which includes quasars observed between September, 2017 and June, 2021. There are in total 13,066 quasars reliably identified, of which 6,685 are newly discovered that are not reported in the SDSS DR14 quasar catalog or Million Quasars catalog. Because LAMOST does not provide accurate absolute flux calibration, we re-calibrate the spectra with the SDSS/Pan-STARRS1 multi-band photometric data. The emission line properties of H$\alpha$, H$\beta$, Mg\,{\sc ii} and C\,{\sc iv}, and the continuum luminosities are measured by fitting the re-calibrated spectra. We also estimate the single-epoch virial black hole masses ($\rm M_{BH}$) using the derived emission line and continuum parameters. This is the first time that the emission line and continuum fluxes were estimated based on LAMOST re-calibrated quasar spectra. The catalog and spectra for these quasars are available online. After the nine-year LAMOST quasar survey, there are in total 56,175 identified quasars, of which 24,127 are newly discovered. The LAMOST quasar survey not only discovers a great number of new quasars, but also provides a database for investigating the spectral variability of the quasars observed by both LAMOST and SDSS, and finding rare quasars including changing-look quasars and broad absorption line quasars.Comment: arXiv admin note: text overlap with arXiv:1811.01570, Accepted by ApJ

The LAMOST Survey of Background Quasars in the Vicinity of the Andromeda and Triangulum Galaxies -- II. Results from the Commissioning Observations and the Pilot Surveys

We present new quasars discovered in the vicinity of the Andromeda and Triangulum galaxies with the LAMOST during the 2010 and 2011 observational seasons. Quasar candidates are selected based on the available SDSS, KPNO 4 m telescope, XSTPS optical, and WISE near infrared photometric data. We present 509 new quasars discovered in a stripe of ~135 sq. deg from M31 to M33 along the Giant Stellar Stream in the 2011 pilot survey datasets, and also 17 new quasars discovered in an area of ~100 sq. deg that covers the central region and the southeastern halo of M31 in the 2010 commissioning datasets. These 526 new quasars have i magnitudes ranging from 15.5 to 20.0, redshifts from 0.1 to 3.2. They represent a significant increase of the number of identified quasars in the vicinity of M31 and M33. There are now 26, 62 and 139 known quasars in this region of the sky with i magnitudes brighter than 17.0, 17.5 and 18.0 respectively, of which 5, 20 and 75 are newly-discovered. These bright quasars provide an invaluable collection with which to probe the kinematics and chemistry of the ISM/IGM in the Local Group of galaxies. A total of 93 quasars are now known with locations within 2.5 deg of M31, of which 73 are newly discovered. Tens of quasars are now known to be located behind the Giant Stellar Stream, and hundreds behind the extended halo and its associated substructures of M31. The much enlarged sample of known quasars in the vicinity of M31 and M33 can potentially be utilized to construct a perfect astrometric reference frame to measure the minute PMs of M31 and M33, along with the PMs of substructures associated with the Local Group of galaxies. Those PMs are some of the most fundamental properties of the Local Group.Comment: 26 pages, 6 figures, AJ accepte