31,926 research outputs found
Influence of psychological coping on survival and recurrence in people with cancer: systematic review
OBJECTIVE: To summarise the evidence on the effect of psychological coping styles (including fighting spirit, helplessness/hopelessness, denial, and avoidance) on survival and recurrence in patients with cancer. DESIGN: Systematic review of published and unpublished prospective observational studies. MAIN OUTCOMES MEASURES: Survival from or recurrence of cancer. RESULTS: 26 studies investigated the association between psychological coping styles and survival from cancer, and 11 studies investigated recurrence. Most of the studies that investigated fighting spirit (10 studies) or helplessness/hopelessness (12 studies) found no significant associations with survival or recurrence. The evidence that other coping styles play an important part was also weak. Positive findings tended to be confined to small or methodologically flawed studies; lack of adjustment for potential confounding variables was common. Positive conclusions seemed to be more commonly reported by smaller studies, indicating potential publication bias. CONCLUSION: There is little consistent evidence that psychological coping styles play an important part in survival from or recurrence of cancer. People with cancer should not feel pressured into adopting particular coping styles to improve survival or reduce the risk of recurrence. [References: 42
A radial mode ultrasonic horn for the inactivation of <i>Escherichia coli</i> K12
Tuned cylindrical radial mode ultrasonic horns offer advantages over ultrasonic probes in the design of flow-through devices for bacterial inactivation. This study presents a comparison of the effectiveness of a radial horn and probe in the inactivation of Escherichia coli K12. The radial horn is designed using finite element analysis and the predicted modal parameters are validated using experimental modal analysis. A validated finite element model of the probe is also presented. Visual studies of the cavitation fields produced by the radial horn and probe are carried out using luminol and also backlighting to demonstrate the advantages of radial horns in producing a more focused cavitation field with widely dispersed streamers. Microbiological studies show that, for the same power density, better inactivation of E. coli K12 is achieved using the radial horn and, also, the radial horn offers greater achievable power density resulting in further improvements in bacterial inactivation. The radial horn is shown to be more effective than the probe device and offers opportunities to design in-line flow-through devices for processing applications
Coarse-grained Interaction Potentials for Anisotropic Molecules
We have proposed an efficient parameterization method for a recent variant of
the Gay-Berne potential for dissimilar and biaxial particles and demonstrated
it for a set of small organic molecules. Compared to the previously proposed
coarse-grained models, the new potential exhibits a superior performance in
close contact and large distant interactions. The repercussions of thermal
vibrations and elasticity has been studied through a statistical method. The
study justifies that the potential of mean force is representable with the same
functional form, extending the application of this coarse-grained description
to a broader range of molecules. Moreover, the advantage of employing
coarse-grained models over truncated atomistic summations with large distance
cutoffs has been briefly studied.Comment: 8 pages, 4 tables and 6 figures. To appear in J. Chem. Phy
Communication Platform Payload Definition (CPPD) study. Volume 3: Addendum
This is Volume 3 (Addendum) of the Ford Aerospace & Communications Corporation Final Report for the Communication Platform Payload Definition (CPPD) Study Program conducted for NASA Lewis Research Center under contract No. NAS3-24235. This report presents the results of the study effort leading to five potential platform payloads to service CONUS and WARC Region 2 traffic demand as projected to the year 2008. The report addresses establishing the data bases, developing service aggregation scenarios, selecting and developing 5 payload concepts, performing detailed definition of the 5 payloads, costing them, identifying critical technology, and finally comparing the payloads with each other and also with non-aggregated equivalent services
New Limits on Local Lorentz Invariance in Mercury and Cesium
We report new bounds on Local Lorentz Invariance (LLI) violation in Cs and
Hg. The limits are obtained through the observation of the the spin- precession
frequencies of 199Hg and 133Cs atoms in their ground states as a function of
the orientation of an applied magnetic field with respect to the fixed stars.
We measure the amplitudes of the dipole couplings to a preferred direction in
the equatorial plane to be 19(11) nHz for Hg and 9(5) microHz for Cs. The upper
bounds established here improve upon previous bounds by about a factor of four.
The improvement is primarily due to mounting the apparatus on a rotating table.
New bounds are established on several terms in the standard model extension
including the first bounds on the spin-couplings of the neutron and proton to
the z direction, <7e-30 GeV and <7e-29 GeV, respectively.Comment: 17 pages, 6 figure
Mode-locked Bloch oscillations in a ring cavity
We present a new technique for stabilizing and monitoring Bloch oscillations
of ultracold atoms in an optical lattice under the action of a constant
external force. In the proposed scheme, the atoms also interact with a
unidirectionally pumped optical ring cavity whose one arm is collinear with the
optical lattice. For weak collective coupling, Bloch oscillations dominate over
the collective atomic recoil lasing instability and develop a synchronized
regime in which the atoms periodically exchange momentum with the cavity field.Comment: 7 pages, 5 figure
Maximum fidelity retransmission of mirror symmetric qubit states
In this paper we address the problem of optimal reconstruction of a quantum state from the result of a single measurement when the original quantum state is known to be a member of some specified set. A suitable figure of merit for this process is the fidelity, which is the probability that the state we construct on the basis of the measurement result is found by a subsequent test to match the original state. We consider the maximisation of the fidelity for a set of three mirror symmetric qubit states. In contrast to previous examples, we find that the strategy which minimises the probability of erroneously identifying the state does not generally maximise the fidelity
New light on the âDrummer of Tedworthâ: conflicting narratives of witchcraft in Restoration England
This paper presents a definitive text of hitherto little-known early documents concerning âThe Drummer of Tedworthâ, a poltergeist case that occurred in 1662-3 and became famous not least due to its promotion by Joseph Glanvill in his demonological work, Saducismus Triumphatus. On the basis of these and other sources, it is shown how responses to the events at Tedworth evolved from anxious piety on the part of their victim, John Mompesson, to confident apologetic by Glanvill, before they were further affected by the emergence of articulate scepticism about the case
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