Geometric Second Order Field Equations for General Tensor Gauge Fields

Higher spin tensor gauge fields have natural gauge-invariant field equations written in terms of generalised curvatures, but these are typically of higher than second order in derivatives. We construct geometric second order field equations and actions for general higher spin boson fields, and first order ones for fermions, which are non-local but which become local on gauge-fixing, or on introducing auxiliary fields. This generalises the results of Francia and Sagnotti to all representations of the Lorentz group.Comment: 34 pages, LaTeX. Reference adde

On Dual Formulation for Higher Spin Gauge Fields in (A)dSd(A)dS_d

We obtain dual actions for spin $s \geq 2$ massless fields in $(A)dS_d$ by solving different algebraic constraints in the same first-order theory. Flat space dual higher spin actions obtained by Boulanger, Cnockaert and Henneaux \cite{BH} by solving differential constraints are shown to result from our formulation in a sort of quasi-classical approximation for the flat limit. The case of $s=2$ is considered in detail.Comment: LaTeX, 13 pages, no figure

Higher-Spin Gauge Interactions for Matter Fields in Two Dimensions

We formulate a new model which describes higher-spin gauge interactions for matter fields in two dimensions. This model is a higher-spin generalization of d2 gravity and turns out to be integrable. No vanishing higher-spin current conditions are imposed on the matter fields.Comment: LaTex, 10 pages, no figures, to be published in Phys. Lett.

High Spin Gauge Fields and Two-Time Physics

All possible interactions of a point particle with background electromagnetic, gravitational and higher-spin fields is considered in the two-time physics worldline formalism in (d,2) dimensions. This system has a counterpart in a recent formulation of two-time physics in non-commutative field theory with local Sp(2) symmetry. In either the worldline or field theory formulation, a general Sp(2) algebraic constraint governs the interactions, and determines equations that the background fields of any spin must obey. The constraints are solved in the classical worldline formalism (h-bar=0 limit) as well as in the field theory formalism (all powers of h-bar). The solution in both cases coincide for a certain 2T to 1T holographic image which describes a relativistic particle interacting with background fields of any spin in (d-1,1) dimensions. Two disconnected branches of solutions exist, which seem to have a correspondence as massless states in string theory, one containing low spins in the zero Regge slope limit, and the other containing high spins in the infinite Regge slope limit.Comment: LaTeX 22 pages. Typos corrected in version

Non-geometric backgrounds, doubled geometry and generalised T-duality

String backgrounds with a local torus fibration such as T-folds are naturally formulated in a doubled formalism in which the torus fibres are doubled to include dual coordinates conjugate to winding number. Here we formulate and explore a generalisation of this construction in which all coordinates are doubled, so that the doubled space is a twisted torus, i.e. a compact space constructed from identifying a group manifold under a discrete subgroup. This incorporates reductions with duality twists, T-folds and a class of flux compactifications, together with the non-geometric backgrounds expected to arise from these through T-duality. It also incorporates backgrounds that are not even locally geometric, and suggests a generalisation of T-duality to a more general context. We discuss the effective field theory arising from such an internal sector, give a world-sheet sigma model formulation of string theory on such backgrounds and illustrate our discussion with detailed examples.Comment: 81 page

Dynamics of Higher Spin Fields and Tensorial Space

The structure and the dynamics of massless higher spin fields in various dimensions are reviewed with an emphasis on conformally invariant higher spin fields. We show that in D=3,4,6 and 10 dimensional space-time the conformal higher spin fields constitute the quantum spectrum of a twistor-like particle propagating in tensorial spaces of corresponding dimensions. We give a detailed analysis of the field equations of the model and establish their relation with known formulations of free higher spin field theory.Comment: JHEP3 style, 40 pages; v2 typos corrected, comments and references added; v3 published versio

Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer.

Bone marrow-derived endothelial progenitor cells (EPCs) infiltrate into sites of neovascularization in adult tissues and mature into functional blood endothelial cells (BECs) during a process called vasculogenesis. Human marrow-derived EPCs have recently been reported to display a mixed myeloid and lymphatic endothelial cell (LEC) phenotype during inflammation-induced angiogenesis; however, their role in cancer remains poorly understood. We report the in vitro differentiation of human cord blood CD133(+)CD34(+) progenitors into podoplanin(+) cells expressing both myeloid markers (CD11b, CD14) and the canonical LEC markers vascular endothelium growth factor receptor 3 (VEGFR-3), lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1), and prospero homeobox 1 (PROX-1). These podoplanin(+) cells displayed sprouting behavior comparable to that of LECs in vitro and a dual hemangiogenic and lymphangiogenic activity in vivo in an endothelial cell sprouting assay and corneal vascularization assay, respectively. Furthermore, these cells expressed vascular endothelium growth factor (VEGF) family members A, -C, and -D. Thus, bone-marrow derived EPCs stimulate hemangiogenesis and lymphangiogenesis through their ability to differentiate into LECs and to produce angiogenic factors. Importantly, plasma from patients with breast cancer induced differentiation of CD34(+) cord blood progenitors into hemangiogenic and lymphangiogenic CD11b(+) myeloid cells, whereas plasma from healthy women did not have this effect. Consistent with these findings, circulating CD11b(+) cells from breast cancer patients, but not from healthy women, displayed a similar dual angiogenic activity. Taken together, our results show that marrow-derived EPCs become hemangiogenic and lymphangiogenic upon exposure to cancer plasma. These newly identified functions of bone-marrow derived EPCs are expected to influence the diagnosis and treatment of breast cancer

Topological A-Type Models with Flux

We study deformations of the A-model in the presence of fluxes, by which we mean rank-three tensors with antisymmetrized upper/lower indices, using the AKSZ construction. Generically these are topological membrane models, and we show that the fluxes are related to deformations of the Courant bracket which generalize the twist by a closed 3-from $H$, in the sense that satisfying the AKSZ master equation implies the integrability conditions for an almost generalized complex structure with respect to the deformed Courant bracket. In addition, the master equation imposes conditions on the fluxes that generalize $dH=0$. The membrane model can be defined on a large class of $U(m)$- and $U(m) \times U(m)$-structure manifolds, including geometries inspired by $(1,1)$ supersymmetric $\sigma$-models with additional supersymmetries due to almost complex (but not necessarily complex) structures in the target space. Furthermore, we show that the model can be defined on three particular half-flat manifolds related to the Iwasawa manifold. When only $H$-flux is turned on it is possible to obtain a topological string model, which we do for the case of a Calabi-Yau with a closed 3-form turned on. The simplest deformation from the A-model is due to the $(2,0)+ (0,2)$ component of a non-trivial $b$-field. The model is generically no longer evaluated on holomorphic maps and defines new topological invariants. Deformations due to $H$-flux can be more radical, completely preventing auxiliary fields from being integrated out.Comment: 30 pages. v2: Improved Version. References added. v3: Minor changes, published in JHE

BPS preons and the AdS-M-algebra

We present here the AdS generalization of BPS preons, which were introduced as the hypothetical constituents of M-theory preserving all but one supersymmetries. Our construction, suggested by the relation of `lower dimensional preons' with higher spin theories, can be considered as a deformation of the M-algebraic description of the single supersymmetry broken by a preon, and provides another reason to identify the AdS generalization of the M-algebra, which we call the AdS-M-algebra, with osp(1|32).Comment: Plain latex, no figures, 19 pages minor corrections, one ref. added, as published in JHEP 04 (2008) 06

An epitaxial model for heterogeneous nucleation on potent substrates

© The Minerals, Metals & Materials Society and ASM International 2012In this article, we present an epitaxial model for heterogeneous nucleation on potent substrates. It is proposed that heterogeneous nucleation of the solid phase (S) on a potent substrate (N) occurs by epitaxial growth of a pseudomorphic solid (PS) layer on the substrate surface under a critical undercooling (ΔT ). The PS layer with a coherent PS/N interface mimics the atomic arrangement of the substrate, giving rise to a linear increase of misfit strain energy with layer thickness. At a critical thickness (h ), elastic strain energy reaches a critical level, at which point, misfit dislocations are created to release the elastic strain energy in the PS layer. This converts the strained PS layer to a strainless solid (S), and changes the initial coherent PS/N interface into a semicoherent S/N interface. Beyond this critical thickness, further growth will be strainless, and solidification enters the growth stage. It is shown analytically that the lattice misfit (f) between the solid and the substrate has a strong influence on both h and ΔT ; h decreases; and ΔT increases with increasing lattice misfit. This epitaxial nucleation model will be used to explain qualitatively the generally accepted experimental findings on grain refinement in the literature and to analyze the general approaches to effective grain refinement.EPSRC Centre for Innovative Manufacturing in Liquid Metal Engineerin