8,800 research outputs found
Strengthen the construction of professional connotation and improve service quality
为进一步提高医院消毒供应中心的服务质量,笔者总结分析了消毒供应中心加强质量管理的方法,以期加强本中心专业内涵建设,强化服务意识,提高服务质量,为临床提供合格的医疗物品,保证患者安全。To further improve the service quality of hospital disinfection and supply center, the author summarizes and analyzes the methods of strengthening quality management in the supply center, with a view to strengthening the construction of the center, enhancing the service consciousness, improving the service quality, providing qualified medical articles for clinic, and ensuring the safety of patients
Understanding Excitation Energy Quenching in IsiA
Cyanobacteria are photoautotrophic organisms that contribute a significant amount of global primary productivity. They are found in freshwater, marine and even some extremely severe environments. Among those environments, iron deficiency is one of the most common stress conditions in cyanobacterial habitats. To survive, cyanobacteria have evolved and developed several strategies to alleviate the damage caused by iron deficiency.
Iron stress-inducible protein (IsiA) is a chlorophyll-binding membrane protein found in cyanobacteria grown in iron-deficient conditions. During the past decades, considerable effort has been put on understanding how IsiA functions to help cyanobacteria survive iron deficiency. It has been reported that IsiA forms various ring-shaped complexes with PSI (PSIx-IsiAy) or by itself (IsiA aggregate). While coupled with PSI (PSIx-IsiAy), the IsiA protein serves as an accessary antenna for PSI, which increases the absorption cross-section by 60% compared with the PSI trimer. IsiA aggregate, instead, dissipates excess light energy to prevent the cells from photodamage. Although these functions have been discovered and demonstrated in vivo and in vitro, the detailed mechanisms, especially the non-photochemical quenching process in IsiA, were not well understood.
In this study, the excitation energy quenching process in IsiA was investigated by time-resolved spectroscopy, and we proposed that IsiA dissipate excitation energy via a cysteine-mediated quenching process. Site-directed mutagenesis was performed to replace this critical cysteine (C260) in IsiA with a valine. This single amino acid substitution in IsiA results in the defective IsiA that no longer quenches excitation energy but still functions as light-harvesting antenna for PSI. Interestingly, this IsiA mutant grew faster than the wild type in the presence of iron under high light, suggesting a more efficient use of light energy due to the abolishment of a photoprotective mechanism.
Sharing a similar structure with IsiA, CP43, an intrinsic antenna of PSII, has not been reported being involved in excitation energy quenching process. We attempted to introduce this cysteine-mediated quenching process into CP43 to directly provide photoprotection to the reaction center of PSII. The mutant CP43 phenotypes showed a 25% lower quantum efficiency of PSII and barely grew photoautotrophically, implying an inefficient energy transfer to the reaction center of PSII caused by the introduction of an extrinsic quenching process
THE NORTHEAST AND INTERREGIONAL COMPETITION FOR BROILERS
An interregional model which minimizes production and transportation costs for broilers was developed and tested. Ten production and 22 consumption regions were defined. The results indicate that current flow patterns are relatively efficient given the existing production capacities. As demand increases the increased production will tend to be in the Southwest (Texas) and to a lesser extent in the Southeast (North Carolina). Shadow prices indicate that in the longer run production in the Northeast will continue to decline in relative terms and perhaps in absolute terms.Resource /Energy Economics and Policy,
-almost periodic and almost periodic solutions for some nonlinear integral equations
In this paper, we investigate the existence of -almost periodic solution for a class of nonlinear Fredholm integral equations, and the existence of almost periodic solution for a class of nonlinear functional integral equations. Our existence theorems extend some earlier results. Two examples are given to illustrate our results
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