9,733 research outputs found
Tailoring Accelerating Beams in Phase Space
An appropriate design of wavefront will enable light fields propagating along
arbitrary trajectories thus forming accelerating beams in free space. Previous
ways of designing such accelerating beams mainly rely on caustic methods, which
start from diffraction integrals and only deal with two-dimensional fields.
Here we introduce a new perspective to construct accelerating beams in phase
space by designing the corresponding Wigner distribution function (WDF). We
find such a WDF-based method is capable of providing both the initial field
distribution and the angular spectrum in need by projecting the WDF into the
real space and the Fourier space respectively. Moreover, this approach applies
to the construction of both two- and three-dimensional fields, greatly
generalizing previous caustic methods. It may therefore open up a new route to
construct highly-tailored accelerating beams and facilitate applications
ranging from particle manipulation and trapping to optical routing as well as
material processing.Comment: 8 pages, 6 figure
Fully integrated microsystem for bacterial genotyping
Methods for bacterial detection and identification has garnered renewed interest in recent years due to the infections they may cause and the antimicrobial resistances they can develop, the potential for bioterrorism threats and possible contamination of food/water supplies. Therefore, the rapid, specific and accurate detection of pathogens is crucial for the prevention of pathogen-related disease outbreaks and facilitating disease management as well as the containment of suspected contaminated food and/or water supplies. In this dissertation an integrated modular-based microfluidic system composed of a fluidic cartridge and a control instrument has been developed for bacterial pathogen detection. The integrated system can directly carry out the entire molecular processing pipeline in a single disposable fluidic cartridge and can detect sequence variations in selected genes to allow for the identification of the bacterial species and even its strain. The unique aspect of this fluidic cartridge is its modular format with a task-specific module interconnected to a fluidic motherboard to permit the selection of a material appropriate for the given processing step(s). In addition, to minimize the amount of finishing steps for assembling the fluidic cartridge, many of the functional components were produced during the polymer molding step used to create the fluidic network. The operation of the fluidic cartridge was provided by electronic, mechanical, optical and hydraulic controls located off-chip and assembled into a small footprint instrument. The fluidic cartridge was capable of performing cell lysis, solidphase extraction of genomic DNA from the whole cell lysate, continuous flow PCR amplification of specific gene fragments, continuous flow ligase detection reaction to discriminate sequence variations and universal DNA array readout, which consisted of DNA probes patterned onto a planar polymer waveguide for evanescent excitation. The performance of the fluidic system was demonstrated through its successful application to the genetic detection of bacterial pathogens, such as Escherichia coli O157:H7, Salmonella, methicillin-resistant Staphylococcus aureus and multi-drug resistant Mycobacterium tuberculosis, which are major threats for global heath. The modular system, which could successfully identify several strains of bacteria in \u3c40 min with minimal human intervention and also perform strain identification, represents a significant contribution to pathogen detection
Does unemployment have asymmetric effects on suicide rates? Evidence from the United States: 1928â2013
This study applied the recently developed asymmetric causality
test and asymmetric generalised impulse-response method to
demonstrate the dynamic relationship between unemployment and
suicide rates in the U.S. over the period of 1928â2013. The results
suggest that there exist asymmetric effects of unemployment
on suicide rates. An economic recession (in terms of an increase
in unemployment rate) is more likely to increase the suicide rate
among an old age group (55â64 years old) than among other age
groups, while an economic expansion (in terms of a decrease in
unemployment rate) is more likely to reduce the suicide rate of young
(15â24 and 25â34 years old) and middle age groups (35â44 and 45â
54 years old) than their counterpart. Therefore, policy implications
generated from our results include the following: that intervention
to prevent suicidal behaviour should be directed more towards the
older age group during economic recession and that we may expect
that an economic expansion may not result in a great reduction of
suicide rates for the old age (55â64 years) group
Foreign Is Not Unfamiliar. A Translation Impact Study Involving Taiwan Subjects
The research discussed in this paper is the last of a trilogy investigating the impact of foreignized and domesticated translations on sampled readers. The two precursors had been conducted in two Chinese Mainland cities (Beijing and Guangzhou) and this last one was conducted in the Taiwanese city of Douliou. Therefore, comparisons can be made with the two precursors in the discussion of the research procedure and findings of the Taiwan project. The paper begins with a brief introduction of the background in which the Taiwan project was conceived and a brief profile of the subjects sampled for the project. Then there is a description of the research design, including the hypotheses and field work methodology. Four hypotheses were tested: a) the subjects would have distinguishable ideas about the two renditions; b) they would have a more intense feeling of exoticism when reading the foreignized rendition; c) their degree of sensing the rendition to be exotic or not would be correlated with their other socio-linguistic perceptions of that text; d) the findings of the present investigation would corroborate those obtained from the two precursors. The description of the research design is followed by a presentation of the data analysis conducted for the project together with a statement of the conventions adopted for reading the statistics. Based on the data analysis, interpretations are made in relation to the hypotheses.Le prĂ©sent article fait Ă©tat des travaux issus du troisiĂšme volet dâune recherche portant sur les effets de traductions « étrangĂ©isĂ©es » ou naturalisĂ©es, qui ont Ă©tĂ© observĂ©s chez un Ă©chantillon de lecteurs. Les deux premiers volets de cette recherche avaient Ă©tĂ© menĂ©s dans deux villes de Chine continentale (Beijing et Guangzhou), tandis que le troisiĂšme volet a Ă©tĂ© rĂ©alisĂ© Ă Douliou, Ă Taiwan. Il est ainsi possible de comparer les rĂ©sultats Ă ceux qui ont Ă©tĂ© obtenus antĂ©rieurement. Lâarticle introduit briĂšvement le contexte du projet menĂ© Ă Taiwan ainsi quâun bref profil des sujets participants. Le plan de lâĂ©tude est ensuite prĂ©sentĂ©, y compris les hypothĂšses et la mĂ©thodologie de collecte des donnĂ©es. Quatre hypothĂšses ont Ă©tĂ© testĂ©es : a) les sujets distinguent clairement les deux modes de traduction ; b) ils Ă©prouvent davantage un sentiment dâexotisme Ă la lecture de la version Ă©trangĂ©isĂ©e ; c) leur opinion quant au caractĂšre exotique ou non de la traduction est corrĂ©lĂ©e aux autres caractĂ©ristiques sociolinguistiques perçues pour le texte ; d) les rĂ©sultats de la prĂ©sente Ă©tude corroborent ceux qui ont Ă©tĂ© obtenus dans le cadre des deux premiers volets. La description du plan de lâĂ©tude est suivie de la prĂ©sentation de lâanalyse des donnĂ©es, laquelle est accompagnĂ©e des conventions nĂ©cessaires Ă lâinterprĂ©tation des calculs statistiques. LâinterprĂ©tation des rĂ©sultats au regard des hypothĂšses avancĂ©es se fonde sur cette analyse
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