3,271 research outputs found
Emerging sensor-cloud technology for pervasive services and applications
This is an Editorial article for the Special Issue on "Emerging Sensor-Cloud Technology for Pervasive Services and Applications" of the International Journal of Distributed Sensor Networks
Electronic density of states derived from thermodynamic critical field curves for underdoped La-Sr-Cu-O
Thermodynamic critical field curves have been measured for
over the full range of carrier concentrations
where superconductivity occurs in order to determine changes in the normal
state density of states with carrier concentration. There is a substantial
window in the plane where the measurements are possible because the
samples are both thermodynamically reversible and the temperature is low enough
that vortex fluctuations are not important. In this window, the data fit
Hao-Clem rather well, so this model is used to determine and
for each temperature and carrier concentration. Using N(0) and the ratio of the
energy gap to transition temperature, , as fitting
parameters, the curves give over the
whole range of . Values of N(0) remain rather constant in the optimum-doped
and overdoped regime, but drops quickly toward zero in the underdoped regime.
Modulated structures in electroconvection in nematic liquid crystals
Motivated by experiments in electroconvection in nematic liquid crystals with
homeotropic alignment we study the coupled amplitude equations describing the
formation of a stationary roll pattern in the presence of a weakly-damped mode
that breaks isotropy. The equations can be generalized to describe the planarly
aligned case if the orienting effect of the boundaries is small, which can be
achieved by a destabilizing magnetic field. The slow mode represents the
in-plane director at the center of the cell. The simplest uniform states are
normal rolls which may undergo a pitchfork bifurcation to abnormal rolls with a
misaligned in-plane director.We present a new class of defect-free solutions
with spatial modulations perpendicular to the rolls. In a parameter range where
the zig-zag instability is not relevant these solutions are stable attractors,
as observed in experiments. We also present two-dimensionally modulated states
with and without defects which result from the destabilization of the
one-dimensionally modulated structures. Finally, for no (or very small)
damping, and away from the rotationally symmetric case, we find static chevrons
made up of a periodic arrangement of defect chains (or bands of defects)
separating homogeneous regions of oblique rolls with very small amplitude.
These states may provide a model for a class of poorly understood stationary
structures observed in various highly-conducting materials ("prechevrons" or
"broad domains").Comment: 13 pages, 13 figure
Snap evaporation of droplets on smooth topographies
Droplet evaporation on solid surfaces is important in many applications including printing, micro-patterning and cooling. While seemingly simple, the configuration of evaporating droplets on solids is difficult to predict and control. This is because evaporation typically proceeds as a “stick-slip” sequence—a combination of pinning and de-pinning events dominated by static friction or “pinning”, caused by microscopic surface roughness. Here we show how smooth, pinning-free, solid surfaces of non-planar topography promote a different process called snap evaporation. During snap evaporation a droplet follows a reproducible sequence of configurations, consisting of a quasi-static phase-change controlled by mass diffusion interrupted by out-of-equilibrium snaps. Snaps are triggered by bifurcations of the equilibrium droplet shape mediated by the underlying non-planar solid. Because the evolution of droplets during snap evaporation is controlled by a smooth topography, and not by surface roughness, our ideas can inspire programmable surfaces that manage liquids in heat- and mass-transfer applications
Development of a novel 3D culture system for screening features of a complex implantable device for CNS repair
Tubular scaffolds which incorporate a variety of micro- and nanotopographies have a wide application potential in tissue engineering especially for the repair of spinal cord injury (SCI). We aim to produce metabolically active differentiated tissues within such tubes, as it is crucially important to evaluate the biological performance of the three-dimensional (3D) scaffold and optimize the bioprocesses for tissue culture. Because of the complex 3D configuration and the presence of various topographies, it is rarely possible to observe and analyze cells within such scaffolds in situ. Thus, we aim to develop scaled down mini-chambers as simplified in vitro simulation systems, to bridge the gap between two-dimensional (2D) cell cultures on structured substrates and three-dimensional (3D) tissue culture. The mini-chambers were manipulated to systematically simulate and evaluate the influences of gravity, topography, fluid flow, and scaffold dimension on three exemplary cell models that play a role in CNS repair (i.e., cortical astrocytes, fibroblasts, and myelinating cultures) within a tubular scaffold created by rolling up a microstructured membrane. Since we use CNS myelinating cultures, we can confirm that the scaffold does not affect neural cell differentiation. It was found that heterogeneous cell distribution within the tubular constructs was caused by a combination of gravity, fluid flow, topography, and scaffold configuration, while cell survival was influenced by scaffold length, porosity, and thickness. This research demonstrates that the mini-chambers represent a viable, novel, scale down approach for the evaluation of complex 3D scaffolds as well as providing a microbioprocessing strategy for tissue engineering and the potential repair of SCI
Slightly Non-Minimal Dark Matter in PAMELA and ATIC
We present a simple model in which dark matter couples to the standard model
through a light scalar intermediary that is itself unstable. We find this model
has several notable features, and allows a natural explanation for a surplus of
positrons, but no surplus of anti-protons, as has been suggested by early data
from PAMELA and ATIC. Moreover, this model yields a very small nucleon
coupling, well below the direct detection limits. In this paper we explore the
effect of this model in both the early universe and in the galaxy.Comment: 7 pages, 6 figures, v3: updated for new data, added discussion of
Ferm
The Supersymmetric Standard Models with Decay and Stable Dark Matters
We propose two supersymmetric Standard Models (SMs) with decaying and stable
dark matter (DM) particles. To explain the SM fermion masses and mixings and
have a heavy decay DM particle S, we consider the Froggatt-Nielsen mechanism by
introducing an anomalous U(1)_X gauge symmetry. Around the string scale, the
U(1)_X gauge symmetry is broken down to a Z_2 symmetry under which S is odd
while all the SM particles are even. S obtains a vacuum expectation value
around the TeV scale, and then it can three-body decay dominantly to the
second/third family of the SM leptons in Model I and to the first family of the
SM leptons in Model II. Choosing a benchmark point in the constrained minimal
supersymmetric SM with exact R parity, we show that the lightest neutralino DM
is consistent with the CDMS II experiment. Considering S three-body decay and
choosing suitable parameters, we show that the PAMELA and Fermi-LAT experiments
and the PAMELA and ATIC experiments can be explained in Model I and Model II,
respectively.Comment: RevTex4, 26 pages, 6 figures, references added, version to appear in
EPJ
Three-dimensional pattern formation, multiple homogeneous soft modes, and nonlinear dielectric electroconvection
Patterns forming spontaneously in extended, three-dimensional, dissipative
systems are likely to excite several homogeneous soft modes (
hydrodynamic modes) of the underlying physical system, much more than quasi
one- and two-dimensional patterns are. The reason is the lack of damping
boundaries. This paper compares two analytic techniques to derive the patten
dynamics from hydrodynamics, which are usually equivalent but lead to different
results when applied to multiple homogeneous soft modes. Dielectric
electroconvection in nematic liquid crystals is introduced as a model for
three-dimensional pattern formation. The 3D pattern dynamics including soft
modes are derived. For slabs of large but finite thickness the description is
reduced further to a two-dimensional one. It is argued that the range of
validity of 2D descriptions is limited to a very small region above threshold.
The transition from 2D to 3D pattern dynamics is discussed. Experimentally
testable predictions for the stable range of ideal patterns and the electric
Nusselt numbers are made. For most results analytic approximations in terms of
material parameters are given.Comment: 29 pages, 2 figure
An Engineered Approach to Stem Cell Culture: Automating the Decision Process for Real-Time Adaptive Subculture of Stem Cells
Current cell culture practices are dependent upon human operators and remain laborious and highly subjective, resulting in large variations and inconsistent outcomes, especially when using visual assessments of cell confluency to determine the appropriate time to subculture cells. Although efforts to automate cell culture with robotic systems are underway, the majority of such systems still require human intervention to determine when to subculture. Thus, it is necessary to accurately and objectively determine the appropriate time for cell passaging. Optimal stem cell culturing that maintains cell pluripotency while maximizing cell yields will be especially important for efficient, cost-effective stem cell-based therapies. Toward this goal we developed a real-time computer vision-based system that monitors the degree of cell confluency with a precision of 0.791±0.031 and recall of 0.559±0.043. The system consists of an automated phase-contrast time-lapse microscope and a server. Multiple dishes are sequentially imaged and the data is uploaded to the server that performs computer vision processing, predicts when cells will exceed a pre-defined threshold for optimal cell confluency, and provides a Web-based interface for remote cell culture monitoring. Human operators are also notified via text messaging and e-mail 4 hours prior to reaching this threshold and immediately upon reaching this threshold. This system was successfully used to direct the expansion of a paradigm stem cell population, C2C12 cells. Computer-directed and human-directed control subcultures required 3 serial cultures to achieve the theoretical target cell yield of 50 million C2C12 cells and showed no difference for myogenic and osteogenic differentiation. This automated vision-based system has potential as a tool toward adaptive real-time control of subculturing, cell culture optimization and quality assurance/quality control, and it could be integrated with current and developing robotic cell cultures systems to achieve complete automation
Dark matter and sub-GeV hidden U(1) in GMSB models
Motivated by the recent PAMELA and ATIC data, one is led to a scenario with
heavy vector-like dark matter in association with a hidden sector
below GeV scale. Realizing this idea in the context of gauge mediated
supersymmetry breaking (GMSB), a heavy scalar component charged under
is found to be a good dark matter candidate which can be searched for direct
scattering mediated by the Higgs boson and/or by the hidden gauge boson. The
latter turns out to put a stringent bound on the kinetic mixing parameter
between and : . For the typical range
of model parameters, we find that the decay rates of the ordinary lightest
neutralino into hidden gauge boson/gaugino and photon/gravitino are comparable,
and the former decay mode leaves displaced vertices of lepton pairs and missing
energy with distinctive length scale larger than 20 cm for invariant lepton
pair mass below 0.5 GeV. An unsatisfactory aspect of our model is that the
Sommerfeld effect cannot raise the galactic dark matter annihilation by more
than 60 times for the dark matter mass below TeV.Comment: 1+15 pages, 4 figures, version published in JCAP, references added,
minor change
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