5,455 research outputs found
The genetic architecture underlying the evolution of a rare piscivorous life history form in brown trout after secondary contact and strong introgression
Identifying the genetic basis underlying phenotypic divergence and reproductive isolation is a longstanding problem in evolutionary biology. Genetic signals of adaptation and reproductive isolation are often confounded by a wide range of factors, such as variation in demographic history or genomic features. Brown trout ( ) in the Loch Maree catchment, Scotland, exhibit reproductively isolated divergent life history morphs, including a rare piscivorous (ferox) life history form displaying larger body size, greater longevity and delayed maturation compared to sympatric benthivorous brown trout. Using a dataset of 16,066 SNPs, we analyzed the evolutionary history and genetic architecture underlying this divergence. We found that ferox trout and benthivorous brown trout most likely evolved after recent secondary contact of two distinct glacial lineages, and identified 33 genomic outlier windows across the genome, of which several have most likely formed through selection. We further identified twelve candidate genes and biological pathways related to growth, development and immune response potentially underpinning the observed phenotypic differences. The identification of clear genomic signals divergent between life history phenotypes and potentially linked to reproductive isolation, through size assortative mating, as well as the identification of the underlying demographic history, highlights the power of genomic studies of young species pairs for understanding the factors shaping genetic differentiation
What is a categorical model of arrows?
We investigate what the correct categorical formulation of Hughesâ Arrows should be. It has long been folklore that Arrows, a functional programming construct, and Freyd categories, a categorical notion due to Power, Robinson and Thielecke, are somehow equivalent. In this paper, we show that the situation is more subtle. By considering Arrows wholly within the base category we derive two alternative formulations of Freyd category that are equivalent to Arrowsâenriched Freyd categories and indexed Freyd categories. By imposing a further condition, we characterise those indexed Freyd categories that are isomorphic to Freyd categories. The key differentiating point is the number of inputs available to a computation and the structure available on them, where structured input is modelled using comonads
Reviews
Integrating Information Technology into Education edited by Deryn Watson and David Tinsley, London, Chapman & Hall, 1995, ISBN: 0â412â62250â5, 316 pages
Dance for Health: the impact of creative dance sessions on older people in an acute hospital setting
Background: This service evaluation examined the impact of Dance for Health, a programme of weekly group dance sessions for older patients, which took place on wards in an acute hospital setting.
Methods: Qualitative and quantitative observations using the ArtsObs scale were undertaken of 64 dance sessions over a 12-week period involving seven different hospital wards encompassing 313 patient attendances.
Results: Statistically significant improvements were observed in the mood of the majority of patients taking part. People engaged mentally and physically with the activity were distracted from their medical condition and from what was happening on the ward. Patients appeared relaxed and were willing to express themselves creatively.
Conclusion: The Dance for Health programme had a positive impact on group participants, promoting movement and physical activity for older patients. It is a meaningful and enjoyable activity, which encourages social interaction and provides respite from the medical environment
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Institutionalization and Sustainability of the National Science Foundation's Advanced Technological Education program
This three-year study closely examined six ATE projects and four national centers. The analysis was specifically concerned with the ability of the ATE projects and centers to meet the program's goal of having a significant and permanent influence on the host colleges and on the system of science, technology, engineering, and mathematics education (STEM) in general. Thus, the report discusses (1) the institutionalization of the projects and centers--the extent to which their activities are becoming incorporated into the normal, ongoing activities of the host community colleges; and (2) their sustainability--the extent to which the major activities of the ATE program continue after the NSF grant expires. The report concludes that the ATE program has an impressive record of accomplishment, particularly in the influence it has had on curriculum and professional development, and on bringing together community colleges, universities, high schools, businesses, and other groups in a unique initiative to improve the education of our nation's STEM technicians
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The Landscape of Noncredit Workforce Education: State Policies and Community College Practices
Postsecondary noncredit education has become increasingly common in recent years, and at many community colleges, noncredit programs enroll more students than do credit programs (Bailey et al., 2003). Courses connected with workforce instruction and contract training account for much of this growth (Dougherty and Bakia, 1999), and such courses are noted for their important role in responding flexibly to shifting workforce demands. Still, the growth in community college noncredit workforce education raises questions about whether the colleges are keeping pace with student and industry needs, using resources efficiently, and providing adequate access to all students. The answers to these questions may challenge current state policies and college practices
Enhanced Autocompensating Quantum Cryptography System
We have improved the hardware and software of our autocompensating system for
quantum key distribution by replacing bulk optical components at the end
stations with fiber-optic equivalents and implementing software that
synchronizes end-station activities, communicates basis choices, corrects
errors and performs privacy amplification over a local area network. The all
fiber-optic arrangement provides stable, efficient and high-contrast routing of
the photons. The low bit error rate leads to high error correction efficiency
and minimizes data sacrifice during privacy amplification. Characterization
measurements made on a number of commercial avalanche photodiodes are presented
that highlight the need for improved devices tailored specifically for quantum
information applications. A scheme for frequency shifting the photons returning
from Alice's station to allow them to be distinguished from backscattered noise
photons is also described.
OCIS codes: 030.5260, 060.0060, 060.2360, 230.2240, 270.5570.Comment: 13 pages, 1 table, 9 figures; Applied Optics LP (in press, to appear
3/02
Daylight quantum key distribution over 1.6 km
Quantum key distribution (QKD) has been demonstrated over a point-to-point
-km atmospheric optical path in full daylight. This record
transmission distance brings QKD a step closer to surface-to-satellite and
other long-distance applications.Comment: 4 pages, 2 figures, 1 table. Submitted to PRL on 14 January 2000 for
publication consideratio
TEOS: A framework for constructing operational definitions of medication adherence based on Timelines â Events â Objectives â Sources
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