2,934 research outputs found
Mapping out the time-evolution of exoplanet processes
There are many competing theories and models describing the formation,
migration and evolution of exoplanet systems. As both the precision with which
we can characterize exoplanets and their host stars, and the number of systems
for which we can make such a characterization increase, we begin to see
pathways forward for validating these theories. In this white paper we identify
predicted, observable correlations that are accessible in the near future,
particularly trends in exoplanet populations, radii, orbits and atmospheres
with host star age. By compiling a statistically significant sample of
well-characterized exoplanets with precisely measured ages, we should be able
to begin identifying the dominant processes governing the time-evolution of
exoplanet systems.Comment: Astro2020 white pape
HOMO band structure and anisotropic effective hole mass in thin crystalline Pentacene films
The band dispersion of the two highest occupied molecular orbital
(HOMO)-derived bands in thin crystalline Pentacene films grown on Bi(001) was
determined by photoemission spectroscopy. Compared to first-principles
calculations our data show a significantly smaller band width and a much larger
band separation indicating that the molecular interactions are weaker than
predicted by theory--a direct contradiction to previous reports by Kakuta et
al. [Phys. Rev. Lett. 98, 247601 (2007)]. The effective hole mass m* at M-bar
is found to be anisotropic and larger than theoretically predicted. Comparison
of m* to field effect mobility measurements shows that the band structure has a
strong influence on the mobility even at room temperature where we estimate the
scattering rate to be tau ~3 fs.Comment: 20 pages, 4 figures, 1 table and appendi
Electron-phonon coupling in crystalline Pentacene films
The electron-phonon(e-p) interaction in Pentacene (Pn) films grown on Bi(001)
was investigated using photoemission spectroscopy. The spectra reveal thermal
broadening from which we determine an e-p mass enhancement factor of lambda =
0.36 +/- 0.05 and an effective Einstein energy of omega_E = 11 +/- 4 meV. From
omega_E it is inferred that dominant contributions to the e-p effects observed
in ARPES come from intermolecular vibrations. Based on the experimental data
for lambda we extract an effective Peierls coupling value of g_eff = 0.55. The
e-p coupling narrows the HOMO band width by 15 +/- 8% between 75K and 300K.Comment: 19 pages, 5 figures and supplementary informatio
High-resolution spectroscopy of V854 Cen in decline - Absorption and emission lines of C_2 molecules
High-resolution optical spectra of the R Coronae Borealis (RBC) star V854
Centauri in the early stages of a decline show, in addition to the features
reported for other RCBs in decline, narrow absorption lines from the C_2
Phillips system. The low rotational temperature, T_rot = 1150K, of the C_2
ground electronic state suggests the cold gas is associated with the developing
shroud of carbon dust. These absorption lines were not seen at a fainter
magnitude on the rise from minimum light nor at maximum light. This is the
first detection of cold gas around a RCB star.Comment: 5 pages, 5 figures, accepted for publication by Monthly Notices of
the Royal Society of Astronom
Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing
© 2008 Huse et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License. The definitive version was published in PLoS Genetics 4 (2008): e1000255, doi:10.1371/journal.pgen.1000255.Massively parallel pyrosequencing of hypervariable regions from small subunit ribosomal RNA (SSU rRNA) genes can sample a microbial community two or three orders of magnitude more deeply per dollar and per hour than capillary sequencing of full-length SSU rRNA. As with full-length rRNA surveys, each sequence read is a tag surrogate for a single microbe. However, rather than assigning taxonomy by creating gene trees de novo that include all experimental sequences and certain reference taxa, we compare the hypervariable region tags to an extensive database of rRNA sequences and assign taxonomy based on the best match in a Global Alignment for Sequence Taxonomy (GAST) process. The resulting taxonomic census provides information on both composition and diversity of the microbial community. To determine the effectiveness of using only hypervariable region tags for assessing microbial community membership, we compared the taxonomy assigned to the V3 and V6 hypervariable regions with the taxonomy assigned to full-length SSU rRNA sequences isolated from both the human gut and a deep-sea hydrothermal vent. The hypervariable region tags and full-length rRNA sequences provided equivalent taxonomy and measures of relative abundance of microbial communities, even for tags up to 15% divergent from their nearest reference match. The greater sampling depth per dollar afforded by massively parallel pyrosequencing reveals many more members of the ârare biosphereâ than does capillary sequencing of the full-length gene. In addition, tag sequencing eliminates cloning bias and the sequences are short enough to be completely sequenced in a single read, maximizing the number of organisms sampled in a run while minimizing chimera formation. This technique allows the cost-effective exploration of changes in microbial community structure, including the rare biosphere, over space and time and can be applied immediately to initiatives, such as the Human Microbiome Project.Woods Hole Center for Oceans and Human Health from the National Institutes of Health and National Science Foundation (NIH/NIEHS 1 P50 ES012742-01 and NSF/OCE 0430724-J Stegeman PI to MLS). NIH Director's Pioneer Award and Doris Duke Distinguished Clinical Scientist Award to DAR
Shape of the acoustic gravitational wave power spectrum from a first order phase transition
We present results from large-scale numerical simulations of a first order thermal phase transition in the early Universe, in order to explore the shape of the acoustic gravitational wave and the velocity power spectra. We compare the results with the predictions of the recently proposed sound shell model. For the gravitational wave power spectrum, we find that the predicted k(-3) behavior, where k is the wave number, emerges clearly for detonations. The power spectra from deflagrations show similar features, but exhibit a steeper high-k decay and an extra feature not accounted for in the model. There are two independent length scales: the mean bubble separation and the thickness of the sound shell around the expanding bubble of the low temperature phase. It is the sound shell thickness which sets the position of the peak of the power spectrum. The low wave number behavior of the velocity power spectrum is consistent with a causal k(3), except for the thinnest sound shell, where it is steeper. We present parameters for a simple broken power law fit to the gravitational wave power spectrum for wall speeds well away from the speed of sound where this form can be usefully applied. We examine the prospects for the detection, showing that a LISA-like mission has the sensitivity to detect a gravitational wave signal from sound waves with an RMS fluid velocity of about 0.05c, produced from bubbles with a mean separation of about 10(-2) of the Hubble radius. The shape of the gravitational wave power spectrum depends on the bubble wall speed, and it may be possible to estimate the wall speed, and constrain other phase transition parameters, with an accurate measurement of a stochastic gravitational wave background.Peer reviewe
The Interplay between Child Maltreatment and Stressful Life Events during Adulthood and Cardiovascular ProblemsâA Representative Study
Psychological stress is a major risk factor for cardiovascular diseases. While the relevance of early life stress, such as that which is due to child maltreatment (CM), is well known to impact individual stress responses in the long-term, and data on the interplay between CM and stressful events in adulthood on cardiovascular health are sparse. Here, we aimed to assess how stressful life events in adulthood are associated with cardiovascular health infarction in later life and whether this association is independent of CM. In a cross-sectional design, a probability sample of the German population above the age of 14 was drawn using different sampling steps. The final sample included 2510 persons (53.3% women, mean age: 48.4 years). Participants were asked about sociodemographic factors, adult life events, CM, and health conditions in adulthood. Results indicate that the number of experienced adverse life events in adulthood is associated with significantly increased odds for obesity (Odds Ration (OR)women = 1.6 [1.3; 2.0], ORmen = 1.4 [1.1; 1.9]), diabetes (ORwomen = 1.5 [1.1; 2.1], ORmen = 1.5 [1.1; 2.3]) and myocardial infarction (ORwomen = 2.1 [1.0; 4.3], ORmen = 1.8 [1.1; 2.8]). This association is not moderated by the experience of CM, which is associated with cardiovascular problems independently. Taken together, adult stressful life events and CM are significantly and independently associated with cardiovascular health in men and women in the German population in a dose-dependent manner. General practitioners, cardiologists and health policy-makers should be aware of this association between psychosocial stressors during childhood and adulthood and cardiovascular health
Axial Seamount
Author Posting. © Oceanography Society, 2010. This article is posted here by permission of Oceanography Society for personal use, not for redistribution. The definitive version was published in Oceanography 23, 1 (2010): 38-39.Axial Seamount is a hotspot volcano
superimposed on the Juan de Fuca Ridge
(JdFR) in the Northeast Pacific Ocean.
Due to its robust magma supply, it rises
~ 800 m above the rest of JdFR and has
a large elongate summit caldera with
two rift zones that parallel and overlap
with adjacent segments of the spreading
center
Accuracy and quality of massively parallel DNA pyrosequencing
© 2007 Huse et al.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The definitive version was published in Genome Biology 8 (2007): R143, doi:10.1186/gb-2007-8-7-r143.Additional data file 1 is a fasta file of the 43 known sequences used. Additional data file 2 is a gzip-compressed fasta file of the sequences output by the GS20. These sequences correspond to those included in Additional data files 3, 4, 5 but include only the final sequence information. Additional data files 3, 4, 5 are three compressed text files representing the text translations of the original GS20 binary output (sff) files for all of the sequencing used in the analysis, including sequence, flowgram and other run information. GS20 data are reported by region of the PicoTiterPlateâą; we sequenced three plate regions.Massively parallel pyrosequencing systems have increased the efficiency of DNA sequencing, although the published per-base accuracy of a Roche GS20 is only 96%. In genome projects, highly redundant consensus assemblies can compensate for sequencing errors. In contrast, studies of microbial diversity that catalogue differences between PCR amplicons of ribosomal RNA genes (rDNA) or other conserved gene families cannot take advantage of consensus assemblies to detect and minimize incorrect base calls.
We performed an empirical study of the per-base error rate for the Roche GS20 system using sequences of the V6 hypervariable region from cloned microbial ribosomal DNA (tag sequencing). We calculated a 99.5% accuracy rate in unassembled sequences, and identified several factors that can be used to remove a small percentage of low-quality reads, improving the accuracy to 99.75% or better.
By using objective criteria to eliminate low quality data, the quality of individual GS20 sequence reads in molecular ecological applications can surpass the accuracy of traditional capillary methods.This work was supported by National Aeronautics and Space Administration Astrobiology Institute Cooperative Agreement NNA04CC04A (to MLS), subcontracts from the Woods Hole Center for Oceans and Human Health from the National Institutes of Health and National Science Foundation (NIH/NIEHS 1 P50 ES012742-01 and NSF/OCE 0430724-J Stegeman PI to HGM and MLS), grants from the WM Keck Foundation and the G Unger Vetlesen Foundation (to MLS), and a National Research Council Research Associateship Award (to JAH)
Vesicle shape, molecular tilt, and the suppression of necks
Can the presence of molecular-tilt order significantly affect the shapes of
lipid bilayer membranes, particularly membrane shapes with narrow necks?
Motivated by the propensity for tilt order and the common occurrence of narrow
necks in the intermediate stages of biological processes such as endocytosis
and vesicle trafficking, we examine how tilt order inhibits the formation of
necks in the equilibrium shapes of vesicles. For vesicles with a spherical
topology, point defects in the molecular order with a total strength of
are required. We study axisymmetric shapes and suppose that there is a
unit-strength defect at each pole of the vesicle. The model is further
simplified by the assumption of tilt isotropy: invariance of the energy with
respect to rotations of the molecules about the local membrane normal. This
isotropy condition leads to a minimal coupling of tilt order and curvature,
giving a high energetic cost to regions with Gaussian curvature and tilt order.
Minimizing the elastic free energy with constraints of fixed area and fixed
enclosed volume determines the allowed shapes. Using numerical calculations, we
find several branches of solutions and identify them with the branches
previously known for fluid membranes. We find that tilt order changes the
relative energy of the branches, suppressing thin necks by making them costly,
leading to elongated prolate vesicles as a generic family of tilt-ordered
membrane shapes.Comment: 10 pages, 7 figures, submitted to Phy. Rew.
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