5 research outputs found

    Aportaciones al conocimiento de la flora muscinal del Pirineo Occidental

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    In this paper we give citations of 122 taxa of mosses, which have been collected in 31 sites in the Western Pyrenees, in Navarra (Northern Spain). 9 of them are new records to the moss flora of Navarra and 2 are new records both for Navarra and for all the Pyrenees. Some of the more noticeable novelties are Dicranum crassifolium Sérgio, Ochyra & Séneca, Orthotrichum acuminatum H. Phillib. and Orthotrichum shawii Wilson

    Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

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    Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

    Aportaciones al conocimiento de la flora muscinal del Pirineo Occidental

    No full text
    In this paper we give citations of 122 taxa of mosses, which have been collected in 31 sites in the Western Pyrenees, in Navarra (Northern Spain). 9 of them are new records to the moss flora of Navarra and 2 are new records both for Navarra and for all the Pyrenees. Some of the more noticeable novelties are Dicranum crassifolium Sérgio, Ochyra & Séneca, Orthotrichum acuminatum H. Phillib. and Orthotrichum shawii Wilson

    Analysis of the bryoflora of Navarra (North of Spain)

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    The knowledge about the bryoflora in both biogeographical zones of Navarra (Eurosiberian and Mediterranean regions) is commented and compared, and pieces of information about our most recent efforts to boost and balance the bryophytic studies in the Mediterranean zone are reported

    Analysis of the bryoflora of Navarra (North of Spain)

    No full text
    The knowledge about the bryoflora in both biogeographical zones of Navarra (Eurosiberian and Mediterranean regions) is commented and compared, and pieces of information about our most recent efforts to boost and balance the bryophytic studies in the Mediterranean zone are reported
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