6,127 research outputs found

    Fault tolerant decentralized H∞ control for symmetric composite systems

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    This note discusses a class of large-scale systems composed of symmetrically interconnected identical subsystems. We consider the decentralized H∞ control design problem and study the fault tolerance of the resulting system. By exploiting the special structure of the systems, a sufficient condition for the existence of a decentralized H∞ controller is derived. Moreover, for the nominal case as well as for contingent situations characterized by control channel failures, the poles and the H∞-norm of the closed-loop system can be calculated easily based on certain systems of reduced dimensions. Consequently, the tolerance to actuator failure can be easily tested.published_or_final_versio

    Mapping the gene for aroma in rice(Oryza sativa L.) by bulk segregation analysis via RAPD markers

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    The sensory qualities of food such as aroma, taste, and texture are the most important criteria for distinguishing Basmati type rices from non-Basmati types. To map the gene(s) controlling aroma, bulked segregant analysis (BSA) using Random Amplified Polymorphic DNA (RAPD) markers was applied in an F2/F3 population of Basmati 370 (aromatic) and IR36 (non-aromatic). DNA samples from homozygous aromatic and homozygous non-aromatic plants identified on the basis of progeny tests were bulked and used for BSA. A total of 550 random primers were used and the primers, AG8 and AN1, produced polymorphism between aromatic and non-aromatic types. Association of AG8-AR, AN1-AR1, and AN1-AR2 with a gene for aroma was determined by surveying F2 individuals. The three RAPD markers AG8-AR, AN1-AR1, and AN1-AR2 were found to be linked to the gene for aroma with a distance of 6.9, 8.9 and 16.4 cM, respectively. Southern analysis with AG8-AR as a probe with 125 F2 individuals confirmed linkage between AG8-AR and the gene for aroma. AG8-AR was mapped on chromosome 8 flanked by two tightly linked markers, RZ617 and RG978, at 2.1 and 1.7 cM distances, respectively, indicating that this gene in Basmati 370 is located on chromosome 8

    Introducing a framework to assess newly created questions with Natural Language Processing

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    Statistical models such as those derived from Item Response Theory (IRT) enable the assessment of students on a specific subject, which can be useful for several purposes (e.g., learning path customization, drop-out prediction). However, the questions have to be assessed as well and, although it is possible to estimate with IRT the characteristics of questions that have already been answered by several students, this technique cannot be used on newly generated questions. In this paper, we propose a framework to train and evaluate models for estimating the difficulty and discrimination of newly created Multiple Choice Questions by extracting meaningful features from the text of the question and of the possible choices. We implement one model using this framework and test it on a real-world dataset provided by CloudAcademy, showing that it outperforms previously proposed models, reducing by 6.7% the RMSE for difficulty estimation and by 10.8% the RMSE for discrimination estimation. We also present the results of an ablation study performed to support our features choice and to show the effects of different characteristics of the questions' text on difficulty and discrimination.Comment: Accepted at the International Conference of Artificial Intelligence in Educatio

    Development of 〈110〉 texture in copper thin films

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    Author name used in this publication: C. H. Woo2001-2002 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    A coupled ensemble filtering and probabilistic collocation approach for uncertainty quantification of hydrological models

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    Natural Science Foundation of China (Nos. 51190095 and 51225904) and the Program for Innovative Research Team in University (IRT1127)

    Tocilizumab Prevents Progression of Early Systemic Sclerosis Associated Interstitial Lung Disease

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    OBJECTIVE: Tocilizumab has demonstrated lung function preservation in two randomized controlled trials in early systemic sclerosis (SSc). This effect has yet to be characterized in terms of quantitative radiographic lung involvement. In this post-hoc analysis, we assess tocilizumab's impact on lung function preservation, stratifying treatment arms by the degree of radiographic lung involvement. METHODS: The focuSSced trial was a phase 3, randomized placebo-controlled trial of tocilizumab in patients with SSc and progressive skin disease. Participants had baseline and serial spirometry along with high resolution chest CT at baseline and week 48. Quantitative interstitial lung disease and fibrosis were derived using computer software. We divided quantitative interstitial lung disease in mild (5-10%), moderate (>10-20%), or severe (>20%) categories. RESULTS: Of 210 participants recruited in the trial, 136 [65%] had interstitial lung disease. The majority of these participants had moderate-to-severe involvement defined by >10% lung involvement (77%). The tocilizumab arm demonstrated preservation of forced vital capacity over 48 weeks (least squared mean change in %predicted = -0.1) compared to placebo (-6.3%). For mild, moderate, and severe QILD, the mean decline in the %pFVC in the tocilizumab arm at 48 weeks were -4.1, 0.7, and 2.1, and in the placebo group were -10.0, -5.7, and -6.7, respectively. Similar treatment-related preservation findings were seen independent of fibrosis severity. CONCLUSION: Tocilizumab in early SSc- associated interstitial lung disease with progressive skin disease stabilized forced vital capacity over 48 weeks, independent of the extent of quantitative radiographic interstitial lung disease or fibrosis

    Malondialdehyde level and some enzymatic activities in subclinical mastitis milk

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    The purpose of this study was to evaluate the changes occurring in milk malondialdehyde (MDA) level and some enzymatic activities as a result of subclinical mastitis (SCM) in dairy cows. A total of 124 milk samples were collected from 124 lactating cows from the same herd in the period between the 2nd week after calving and the 10th week postpartum. They were classified by bacterial culture and the California mastitis test (CMT) as positive were deemed to have glands with SCM, and the periodic incidence rate of SCM was 26.6%. The most common bacterial isolates from SCM cases were Staphylococcus aureus (47%) and coagulase negative Staphylococci (CNS) (27%). The mean level of MDA and activities of lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) were significantly higher in SCM milk than in normal milk, while the mean activity of glutathione peroxidase (GPx) was significantly lower in SCM milk than in normal milk. There were no differences in the activities of superoxide dismutase (SOD) and aspartate aminotransferase (AST) between normal milk and SCM milk. Therefore, the measurement of milk MDA level and GPx, LDH and ALP activities, appears to be a suitable diagnostic method for identifying SCM in dairy cows.Key words: Subclinical mastitis, mastitis diagnostic, etiology, malonaldehyde (MDA), enzym
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